Faculty of Medicine / MEDICINE / BIOSTATISTICS
| Course: | BIOSTATISTICS/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 7927 | Obavezan | 1 | 10 | 2+2+0 |
| Programs | MEDICINE |
| Prerequisites | No |
| Aims | Getting basic and advanced statistical techniques necessary for organizing and conducting medical surveys. Using appropriate statistical techniques in the phase of data editing and processing. Getting some IBM SPSS commands. |
| Learning outcomes | |
| Lecturer / Teaching assistant | Božidar V. Popović, PhD |
| Methodology | Lectures and exercises. Individual and group work with raw statistical data. |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | The importance of statistics in biomedical surveys. Retrospective and prospective studies. |
| I week exercises | The importance of statistics in biomedical surveys. Retrospective and prospective studies. |
| II week lectures | The basic statistics (mean value, variance, confidence intervals) |
| II week exercises | The basic statistics (mean value, variance, confidence intervals) |
| III week lectures | Median. Percentiles and quartiles. Inter-quartile rank. The distribution function. Normal distribution. |
| III week exercises | Median. Percentiles and quartiles. Inter-quartile rank. The distribution function. Normal distribution. |
| IV week lectures | Symmetric and asymmetric distributions. The estimation of the mean value in case of symmetric and asymmetric distributions. |
| IV week exercises | Symmetric and asymmetric distributions. The estimation of the mean value in case of symmetric and asymmetric distributions. |
| V week lectures | The outliers. The treatments of outliers. |
| V week exercises | The outliers. The treatments of outliers. |
| VI week lectures | Parametric statistics. Statistical hypothesis and test. The first and second kind errors. |
| VI week exercises | Parametric statistics. Statistical hypothesis and test. The first and second kind errors. |
| VII week lectures | t test. t test for two independent samples. t test for two dependent samples. |
| VII week exercises | t test. t test for two independent samples. t test for two dependent samples. |
| VIII week lectures | Analysis of variance. |
| VIII week exercises | Analysis of variance. |
| IX week lectures | Non-parametric statistics. Mann Whitney and Wilcoxon test. |
| IX week exercises | Non-parametric statistics. Mann Whitney and Wilcoxon test. |
| X week lectures | Kruskal Wallis test. |
| X week exercises | Kruskal Wallis test. |
| XI week lectures | Using of the parametrical and non-parametrical statistical techniques in dealing with raw statistical data. |
| XI week exercises | Using of the parametrical and non-parametrical statistical techniques in dealing with raw statistical data. |
| XII week lectures | Correlation analysis. |
| XII week exercises | Correlation analysis. |
| XIII week lectures | Regression analysis. |
| XIII week exercises | Regression analysis. |
| XIV week lectures | The survival function. Kaplan Meier estimation of the survival function. |
| XIV week exercises | The survival function. Kaplan Meier estimation of the survival function. |
| XV week lectures | Contingency tables. The coefficient of contingency and Cramer φ. Risk analysis. |
| XV week exercises | Building of the statistical data base, data processing by means of appropriate statistical techniques. |
| Student workload | In semester Lectures and final exam: (13 h and 20 min) x 16 = 213 h and 20 min. Neophodne pripreme prije početka semestra (administracija, upis, ovjera) 2 x (13 sati i 20 min) = 26 h and 40 min. Total ballast for subject 10 x 30 = 300 h Additional work for repeated exam preparation, including exam preparation is 60 h Ballast structure: 213 h and 20 min (Lectures) + 26 h and 40 min (Preparation) + 60 h (Additional work) |
| Per week | Per semester |
| 10 credits x 40/30=13 hours and 20 minuts
2 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 9 hour(s) i 20 minuts of independent work, including consultations |
Classes and final exam:
13 hour(s) i 20 minuts x 16 =213 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 13 hour(s) i 20 minuts x 2 =26 hour(s) i 40 minuts Total workload for the subject: 10 x 30=300 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 60 hour(s) i 0 minuts Workload structure: 213 hour(s) i 20 minuts (cources), 26 hour(s) i 40 minuts (preparation), 60 hour(s) i 0 minuts (additional work) |
| Student obligations | |
| Consultations | |
| Literature | 1. B. Rosner (2010), Fundamentals in Biostatistics,Cengage Learning 2. A. Field (2013), Discovering Statistics using IBM SPSS Statistics, SAGE Publications |
| Examination methods | Two tests of ten points (20 points in total) Term paper 25 points. Regular lectures presence up to 5 points. Final exam 50 points. Prelazna ocjena se dobija ako se kumulativano sakupi min 50 poena. |
| Special remarks | |
| Comment | In phase of lecturs and exercises all statistical techniques are being ilustrated using IBM SPSS Statistics. |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
Faculty of Medicine / MEDICINE / MEDICAL INFORMATICS
| Course: | MEDICAL INFORMATICS/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 7928 | Obavezan | 1 | 10 | 3+1+0 |
| Programs | MEDICINE |
| Prerequisites | None |
| Aims | The primary educational objectives are to introduce and work with specific software packages and to familiarize students with information systems and information technology used in biomedicine, healthcare, and scientific research. Knowledge: Familiarity with healthcare, hospital, and other information systems; expert systems; artificial intelligence, neurocomputers, databases, and information and communication technologies relevant to biomedicine, healthcare, and biomedical sciences. Skills: Training students to: engage in specific healthcare information systems, use information and communication technology for professional purposes; independently search databases and electronic sources of information and literature; use specific programs for writing and presenting professional and scientific papers. |
| Learning outcomes | After passing this exam, the student will be able to: Use various sources and citation databases for scholarly research Differentiate categories of scientific papers Demonstrate the advantages of digitalization in various aspects of healthcare Explain methods of acquiring medical data using modern devices Understand ways of storing digital patient data and medical history Understand information systems used in different healthcare fields Explain the role of artificial intelligence and expert systems in healthcare Explain the role of robotics and telemedicine |
| Lecturer / Teaching assistant | Prof. dr Ljubiša Stanković (professor), Doc. dr Anđela Draganić (assistant) |
| Methodology | Lectures and exercises. Individual and group work with raw statistical data. Lectures and exercises. Individual and group work with raw statistical data. Lectures and exercises. Individual and group work with raw statistical data. |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | History of Computing. Digitization in Medical Practice. Types of Medical Data. Digital Records of Medical Data. |
| I week exercises | History of Computing. Digitization in Medical Practice. Types of Medical Data. Digital Records of Medical Data. |
| II week lectures | Collecting and Analyzing Digital Data. Analysis of Medical Images. History of Computerized Tomography and Magnetic Resonance Imaging. Modern Devices for Capturing and Processing Medical Images. |
| II week exercises | Collecting and Analyzing Digital Data. Analysis of Medical Images. History of Computerized Tomography and Magnetic Resonance Imaging. Modern Devices for Capturing and Processing Medical Images. |
| III week lectures | Biomedical scientific informatics and biomedical scientific information. Citation databases. Biomedical scientific information system. Studying literature and measuring the quality of papers and journals. |
| III week exercises | Biomedical scientific informatics and biomedical scientific information. Citation databases. Biomedical scientific information system. Studying literature and measuring the quality of papers and journals. |
| IV week lectures | Searching databases and library information system COBISS. Primary, secondary, and tertiary publications. Searching indexing and citation databases: Medline, Web of Science, Scopus, Serbian Citation Index, Hrčak databases, and others. Searching full-text databases. |
| IV week exercises | Searching databases and library information system COBISS. Primary, secondary, and tertiary publications. Searching indexing and citation databases: Medline, Web of Science, Scopus, Serbian Citation Index, Hrčak databases, and others. Searching full-text databases. |
| V week lectures | Citation analyses, evaluation of scientific work, evidence-based medicine and practice, meta-analysis based on published research results. |
| V week exercises | Citation analyses, evaluation of scientific work, evidence-based medicine and practice, meta-analysis based on published research results. |
| VI week lectures | Health information systems. Hospital information systems. Pharmaceutical information system and pharmacoinformatics in the context of modern information technology application. Laboratory information system. Modern information technologies in the management system of medical documentation, electronic records, software for clinic and office management. |
| VI week exercises | Health information systems. Hospital information systems. Pharmaceutical information system and pharmacoinformatics in the context of modern information technology application. Laboratory information system. Modern information technologies in the management system of medical documentation, electronic records, software for clinic and office management. |
| VII week lectures | Application of information and communication technology in specific biomedical scientific fields. |
| VII week exercises | Application of information and communication technology in specific biomedical scientific fields. |
| VIII week lectures | Expert systems. Artificial intelligence and neural networks in biomedicine. |
| VIII week exercises | Expert systems. Artificial intelligence and neural networks in biomedicine. |
| IX week lectures | Decision-making in clinical practice. Application of specialized software tools for decision support. |
| IX week exercises | Decision-making in clinical practice. Application of specialized software tools for decision support. |
| X week lectures | Robotics in medicine. |
| X week exercises | Robotics in medicine. |
| XI week lectures | Telemedicine. |
| XI week exercises | Telemedicine. |
| XII week lectures | Application of information technology in modeling parts of the human body and prosthetic components. |
| XII week exercises | Application of information technology in modeling parts of the human body and prosthetic components. |
| XIII week lectures | Application of information technology and digital innovations in diagnostics and therapy. |
| XIII week exercises | Application of information technology and digital innovations in diagnostics and therapy. |
| XIV week lectures | Mobile applications for monitoring key health parameters of patients. Processing and analysis of collected data. Remote consultations. |
| XIV week exercises | Mobile applications for monitoring key health parameters of patients. Processing and analysis of collected data. Remote consultations. |
| XV week lectures | Final exam. |
| XV week exercises | Final exam. |
| Student workload | Additional work for exam preparation in the retake exam period, including taking the retake exam from 0 to 30 hours (remaining time from the first two items to the total workload for the course) 60 hours and 0 minutes Load structure: 213 hours and 20 minutes (teaching), 26 hours and 40 minutes (preparation), 60 hours and 0 minutes (additional work) |
| Per week | Per semester |
| 10 credits x 40/30=13 hours and 20 minuts
3 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 9 hour(s) i 20 minuts of independent work, including consultations |
Classes and final exam:
13 hour(s) i 20 minuts x 16 =213 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 13 hour(s) i 20 minuts x 2 =26 hour(s) i 40 minuts Total workload for the subject: 10 x 30=300 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 60 hour(s) i 0 minuts Workload structure: 213 hour(s) i 20 minuts (cources), 26 hour(s) i 40 minuts (preparation), 60 hour(s) i 0 minuts (additional work) |
| Student obligations | Students are required to attend lectures, complete practical tasks during exercises, and prepare seminar papers that they publicly present. |
| Consultations | |
| Literature | Edward H. Shortlie, James J. Cimino, “Biomedical Informatics-Computer Applications in Health Care and Biomedicine", Springer ISBN 978-1-4471-4473-1. |
| Examination methods | Attendance at lectures 5, the presence on the exercises 5, essay (written version + oral presentation) 30, PowerPoint presentation 10, exam - test 50 points, a total of 100 points Passing grade can be obtained if the cumulative gathering is min 50 points |
| Special remarks | |
| Comment |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
Faculty of Medicine / MEDICINE / SCIENTIFIC RESEARCH METHODOLOGY
| Course: | SCIENTIFIC RESEARCH METHODOLOGY/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 7929 | Obavezan | 1 | 10 | 2+2+0 |
| Programs | MEDICINE |
| Prerequisites | |
| Aims | Acquiring knowledge and skills, transferring knowledge from the field of methodology of scientific research |
| Learning outcomes | 1. Knows the general methodological principles of scientific research. 2. Knows the types of scientific research and their basic characteristics. 3. Know the ethical standards in biomedical research 4. Know the basic elements of evidence-based medicine. 5. Knows the concept of association and causality, and causality criteria. 6. Knows how to calculate indicators of morbidity and mortality 8. Knows how to describe types of epidemiological studies and their advantages and disadvantages 9. Knows how to differentiate sample types and their application. 10. Knows different types of error of measurement - bias 11. Knows the principles of planning and reporting a scientific-research project. |
| Lecturer / Teaching assistant | prof. dr Dragan Laušević associate prof. dr Boban Mugoša |
| Methodology | Lectures, practice work, seminars, consultations |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | General methodology of scientific research in medicine |
| I week exercises | |
| II week lectures | Classification of scientific research - types of research |
| II week exercises | |
| III week lectures | Evidence based medicine |
| III week exercises | |
| IV week lectures | Important Ethical Standards in Biological and Medical Research |
| IV week exercises | |
| V week lectures | Concept of Association and Causality |
| V week exercises | |
| VI week lectures | Measures of the frequency of a health disorders |
| VI week exercises | |
| VII week lectures | Standardization of measures of morbidity and mortality |
| VII week exercises | |
| VIII week lectures | Sample (type and sample size |
| VIII week exercises | |
| IX week lectures | Descriptive studies |
| IX week exercises | |
| X week lectures | Basic characteristics of various types of observational analytical studies (cohort studies, case controls studies, cross-sectional studies) |
| X week exercises | |
| XI week lectures | Interventional (experimental) studies |
| XI week exercises | |
| XII week lectures | Experiments on animals in laboratory conditions |
| XII week exercises | |
| XIII week lectures | Variability and error of measurement (bias) |
| XIII week exercises | |
| XIV week lectures | Skreening |
| XIV week exercises | |
| XV week lectures | Preparation and submission of a scientific research project |
| XV week exercises |
| Student workload | |
| Per week | Per semester |
| 10 credits x 40/30=13 hours and 20 minuts
2 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 9 hour(s) i 20 minuts of independent work, including consultations |
Classes and final exam:
13 hour(s) i 20 minuts x 16 =213 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 13 hour(s) i 20 minuts x 2 =26 hour(s) i 40 minuts Total workload for the subject: 10 x 30=300 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 60 hour(s) i 0 minuts Workload structure: 213 hour(s) i 20 minuts (cources), 26 hour(s) i 40 minuts (preparation), 60 hour(s) i 0 minuts (additional work) |
| Student obligations | |
| Consultations | permanently by e-mail |
| Literature | |
| Examination methods | 30 points - regular attendance (15), activity during practical work (15) 20 points - seminar 50 points - exam in test form To pass the exam it is necessary to collect a minimum of 50 points cumulatively |
| Special remarks | |
| Comment |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
Faculty of Medicine / MEDICINE / BASICS OF CELL BIOLOGY
| Course: | BASICS OF CELL BIOLOGY/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 7932 | Obavezan | 2 | 5 | 2++0 |
| Programs | MEDICINE |
| Prerequisites | Does not have |
| Aims | Familiarity with modern concepts of cell structure and function. Understanding the principles of cell structure and their importance in the development of new therapeutic options. Getting to know the mutual influence of the cell on the environment and the environment on the cell. Understanding the process of apoptosis and malignant cell alteration. Gaining knowledge about cell receptors and immunity, and the therapeutic importance of developing targeted therapy and immunotherapy of malignant diseases. |
| Learning outcomes | After listening to lectures and exercises, students will be able to understand the complex principles of cell structure, the mutual influence of the cell on the environment and the environment on the cell, understands the process of cell death and apoptosis, and their importance in the practical application of the development of various therapeutic modalities. They are able to apply the acquired knowledge from the process of malignant alteration of cells, cellular immunity and cellular receptors in the planning and execution of scientific research works and projects. |
| Lecturer / Teaching assistant | Prof. dr Filip Vukmirović Prof. dr Vladimir Todorović |
| Methodology | Lectures, exercises, seminars, consultations, seminar papers, presentation in front of the group. |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | Structure and function of cell organelles. |
| I week exercises | Structure and function of cell organelles. |
| II week lectures | Cell damage and adaptation. |
| II week exercises | Cell damage and adaptation. |
| III week lectures | Cell death. |
| III week exercises | Cell death. |
| IV week lectures | Types of necrosis. Apoptosis and its importance in clinical research. |
| IV week exercises | Types of necrosis. Apoptosis and its importance in clinical research. |
| V week lectures | Growth factors and their clinical significance. |
| V week exercises | Growth factors and their clinical significance. |
| VI week lectures | Cell receptors and their importance in disease therapy. |
| VI week exercises | Cell receptors and their importance in disease therapy. |
| VII week lectures | Extracellular matrix and its clinical significance in tumor growth and development. |
| VII week exercises | Extracellular matrix and its clinical significance in tumor growth and development. |
| VIII week lectures | Matrix metalloproteinase in clinical research. |
| VIII week exercises | Matrix metalloproteinase in clinical research. |
| IX week lectures | Angiogenesis. Contemporary concepts of antiangiogenic therapy. |
| IX week exercises | Angiogenesis. Contemporary concepts of antiangiogenic therapy. |
| X week lectures | Cell adhesion molecules and their importance in diagnostics and clinical research. |
| X week exercises | Cell adhesion molecules and their importance in diagnostics and clinical research. |
| XI week lectures | Immunohistochemical methods and analyzes used in diagnostics and clinical research. |
| XI week exercises | Immunohistochemical methods and analyzes used in diagnostics and clinical research. |
| XII week lectures | Principles of tumor biology. |
| XII week exercises | Principles of tumor biology. |
| XIII week lectures | Epidermal growth factor receptor inhibitors. |
| XIII week exercises | Epidermal growth factor receptor inhibitors. |
| XIV week lectures | Cancer stem cells. |
| XIV week exercises | Cancer stem cells. |
| XV week lectures | Mechanisms of resistance to anticancer drugs. |
| XV week exercises | Mechanisms of resistance to anticancer drugs. |
| Student workload | In the semester Teaching and final exam: (6.66 hours) x 16 = 106.56 hours Necessary preparations before the beginning of the semester (administration, enrollment, certification): (6.66 hours) x 2 = 13.32 hours Total workload for the course: 5 x 30 = 150 hours Load structure: 106.56 hours (teaching and final exam) + 13.32 hours (preparation) + 30 hours (additional work) |
| Per week | Per semester |
| 5 credits x 40/30=6 hours and 40 minuts
2 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 4 hour(s) i 40 minuts of independent work, including consultations |
Classes and final exam:
6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work) |
| Student obligations | |
| Consultations | |
| Literature | 1. A. Johnson, J.Lewis, D. Morgan. Molecular Biology of the Cell. Garland Science. Sixth Edition. 2014. |
| Examination methods | Class attendance 20 points, seminar paper 20 points, colloquium 10 points; Final exam (written) up to 50 points. A passed exam means a cumulative score of 50 points or more. |
| Special remarks | |
| Comment |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
Faculty of Medicine / MEDICINE / BASIC OF MOLECULAR GENETICS
| Course: | BASIC OF MOLECULAR GENETICS/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 9118 | Obavezan | 2 | 5 | 2++0 |
| Programs | MEDICINE |
| Prerequisites | No prerequisites required |
| Aims | Course aims: Through this course, doctoral students of medicine and dentistry will be familiar with modern achievements in the field of molecular medicine and genetics, whose achievements are essential in the study of human traits and diseases resulting from changes in the human genome, as well as for the diagnosis and therapy of the disease in man. Students will be introduced to modern methods that are applied in molecular genetics, oncogenetics, immunogenetics, principles of research in medical genetics, principles of genetic information and protecting the confidentiality of genetic data in research and diagnosis and the bioethical principles in medical and clinical genetics. |
| Learning outcomes | After completing the course of molecular genetics in medical research PhD student of medicine and dentistry will be able to: 1. describe and explain the basic principles of molecular genetics, enzyme and gene regulatory systems and epigenetic mechanisms controlling gene expression; 2 define the mechanisms of mutations and repair mechanisms of mutation and design a basic model of research on mutations and their impact on human health; 3. explain the procedures and methods in molecular genetics that are used for analysis and identification of mutations in the human genome; 4. anticipate the importance of genetic research in certain high-risk populations and explain the importance of different research models in medical and molecular genetics; 5. use the relevant literature, databases and professional sites (OMIM, LDDB, POSSUM, ORPHANET); 6. place and set up certain medical-genetic problem and present the results of previous studies and plans to study this issue; 7. recognize bioethical risks and apply bioethical principles in the collection and handling of genetic data and knows how to protect the confidentiality of genetic data in accordance with bioethical principles. |
| Lecturer / Teaching assistant | Full Professor Olivera Miljanović, MD, OhD; Full Professor dr Vladimir Todorović. MD, PhD |
| Methodology | Lectures, workshops, seminars |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | Transfer of genetic information and models of inheritance: the transmission of characteristics, the interpretation of a family tree, complex syndromes. |
| I week exercises | Problem solving: monitoring transmission of characteristics through the generations. Interpretation of family trees and models of inheritance in families. Making family trees and recognition the model of inheritance |
| II week lectures | The organization and function of the human genome: the central dogma of molecular genetics, genetic and epigenetic control of gene expression. |
| II week exercises | Describing the structure of nucleic acids, mechanisms of replication, transcription and translation. genetic information flow from DNA to pproteins, genetic and epigenetic control of gene expression, preservation of genetic information. |
| III week lectures | Mutations in the human genome: mechanisms of origin, type of mutation, DNA repair, gene polymorphisms, genotype-phenotype correlations. |
| III week exercises | Working with patients: identification of phenotye characteristics of patients on the basis of a given genotype and defining the genotype of the patient on the basis of known phenotype. |
| IV week lectures | Chromosomal basis of inheritance: gametogenesis, recombination, silenced genes and genomic imprinting. Molecular cytogenetics: detection and interpretation of chromosomes and microdeletion syndrome. |
| IV week exercises | Identifying chromosomal aberrations based on cytogenetic and FISH microscopic preparations and correlation with fenotype expression. Unusual chromosomal pair XY, X-inactivation. |
| V week lectures | The study of genes and the human genome: The project to human genome mapping, gene maps and genetic markers, sequencing the human genome |
| V week exercises | Displaying and interpretation of genetic map and morbid genome. The project of human genome mapping. Testing of candidate genes for mutations. The role of chromosomal aberrations in the determination of candidate genes and regions. |
| VI week lectures | Methods of molecular genetics in medical research: The isolation, electrophoresis and hybridization of DNA and RNA, DNA and RNA sequences amplification, PCR and Real-Time PCR, sequencing, microarray. |
| VI week exercises | Demonstration of molecular genetics research and diagnostics methods in the laboratory of the Centre for Medical Genetics Centre of Montenegro. |
| VII week lectures | Implementation of molecular genetics methods in the research, diagnosis and treatment of monogenic diseases. |
| VII week exercises | Demonstration of research and diagnostics protocols and indicating the genetic analysis in the diagnosis and prevention of monogenic diseases - demonstration of the use of professional electronic databases: OMIM, POSSUM, LDDB, ORPHANET .... |
| VIII week lectures | Implementation of molecular genetics methods in the research, diagnosis and treatment of monogenic diseases. |
| VIII week exercises | Models of genetic determination, dichotomous vs quantitative traits, polygenic theory, genes and complex traits / diseases, the study of genetic susceptibility to diseases. Oncogenes and tumor suppressor genes - the function and activation. |
| IX week lectures | The medical protocols in the treatment of genomic disorders: identification the population at risk, assessment of risk repetition, diagnosis, registration and prevention of hereditary diseases. |
| IX week exercises | Recognizing the risk of hereditary diseases, setting up a research and diagnostic protocols, genetic risk assessment and genetic information and counseling. Genetic disorder prevention: Prenatal and preimplantation diagnostic. Treatment options: gene ther |
| X week lectures | Gene based therapies and personalized medicine. |
| X week exercises | Demonstration the models of therapy with known genetic entities: the replacement of the missing genes or functions, downstream disease pathology targeting, suppression of unwanted phenotype. |
| XI week lectures | Predictive molecular markers. |
| XI week exercises | Demonstration of clinical and research importance of predictive molecular markers |
| XII week lectures | Oncogenes and tumor suppressor genes - the function and activation. Natural selection and of evolution of cancer |
| XII week exercises | Demonstration of clinical examples (patients) with known molecular mechanisms of cancer. |
| XIII week lectures | Innovative cancer therapies - gene therapy. The efficacy and toxicity of targeted therapies. |
| XIII week exercises | Demonstration of clinical examples (patients): the success and complications of cancer therapy. |
| XIV week lectures | Preclinical studies and early phase clinical trials of drugs. |
| XIV week exercises | Demonstration of the principles of setting up and conducting preclinical and early clinical studies in medicine. |
| XV week lectures | Bioethical principles in medical genetic research, consent to genetic testing, genetic information and confidentiality of genetic data. |
| XV week exercises | Application of bioethical principles in the genetic informind and pre-research informative consent tion and for permission to research, identifying the risks and solving the ethical dilemmas with respect for privacy and human rights. |
| Student workload | Weekly: 10 credits x 40/30 = 13 hours and 20 minutes Structure: 0.75 hours of lectures 0.75 hours of practice 2 hours and 20 minutes of independent analysis exercises 2.5 hours of preparation seminar 2 hour consultation 5 hours of individual work During the semester: Lectures and final exam: 13 hours and 20 minutes x 16 = 214 hours and 20 min. Preparation before the beginning of the semester (administration, enrollment and verification): 2 x 13 hours and 20 min = 26 h 40 min Total workload to the course: 10 x 30 = 300 hours Additional work for preparation of makeup final exam, including the exam taking: 59 hours (the remaining time of the first two items to the total load transfer) Structure: 214 hours and 20 minutes (lectures) + 19 hours 40 minutes (preparation) + 59 hours (additional work) |
| Per week | Per semester |
| 5 credits x 40/30=6 hours and 40 minuts
2 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 4 hour(s) i 40 minuts of independent work, including consultations |
Classes and final exam:
6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work) |
| Student obligations | Students are required to attend lectures, solve the tasks, do one seminar homework with mentor consultation. |
| Consultations | After lectures, seminars and exercises, online and live in agreement with the professor and teaching assistant. |
| Literature | Peter Turnpenny, Sian Ellard: Emerryjeve osnove medicinske genetike. Ur. hrv. izdanja: Bulić-Jakuš F. i Barišić I. Medicinska naklada, Zagreb 2011. ili 15-to izdanje na engleskom jeziku, 2017. R.L. Nussbaum, R.R. McInnes, H.E. Willard: Tompson & Tompson Genetics in medicine, Eight ed. Elsevier, 2016. |
| Examination methods | The forms of knowledge testing and grading: Activity in lectures and seminars 10 points Successfully solving the tasks during classes 20 points Seminar 20 points Final exam 50points Passing grade gets the cumulative set of at least 50 points. |
| Special remarks | |
| Comment | Note: Additional information can be obtained by the subject teacher, head of the study program and the Vice-dean for Academic Affairs. |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
Faculty of Medicine / MEDICINE / POSEBNA POGLAVLJA IZ JAVNOG ZDRAVLJA
| Course: | POSEBNA POGLAVLJA IZ JAVNOG ZDRAVLJA/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 11575 | Obavezan | 2 | 5 | 2++0 |
| Programs | MEDICINE |
| Prerequisites | There is none |
| Aims | The aim of this course is for students to understand and adopt the multidisciplinarity of public health, modern approaches and basic principles of public health sciences, to know how to classify research achievements in the field of public health and to compare public health functions and services of different countries while accepting the public health ethical code. In addition, the goal of the course is to educate students on the implementation of health promotion and disease prevention measures in order to improve health and prevent disease, with special reference to the principles and role in the process of protecting the health of the population. In addition, the goal is to present the basic strategy of public health, as an essential concept of health protection and factors that determine health, as well as to identify methods of suppressing their negative effect on peoples health and life. |
| Learning outcomes | Students gain an understanding and develop critical thinking about how globalization and development affect health and are trained to analyze responses and approaches to current and future global trends that have both positive and negative effects on health and health inequalities. 2. In addition, the expected outcomes refer to the training of people in the community to increase control over their health and to improve it, to strengthen activities to improve health in the community, to implement disease prevention measures and participate in activities to increase the level of information and quantity knowledge about health risk factors and measures to eliminate them. 3. Also, students will be in a position to apply the principles of public health in the areas of their professional activity, to advocate, to initiate, to represent their implementation in all segments of health care. 4. The student will be able to: educate citizens about increasing control over their health, improving health and disease prevention measures; conducts health education activities and supervision of nurses and other staff in the team; advises mothers on the importance of breastfeeding and how to properly feed newborns and infants; assess smoking status, degree of smoking addiction, as well as methods for quitting smoking; identifies alcohol and substance (drug) addicts, adequately approaches these patients and educates vulnerable groups in the prevention of alcohol and drug abuse; educates vulnerable groups (adolescents) about sexually transmitted diseases; understands the principles of proper nutrition and suggests an adequate way of eating to citizens; explain the importance of regular physical activity and its impact on health; explain obesity as a risk factor for contracting mass non-communicable diseases, and to propose non-pharmacological measures for its treatment; identifies people under stress and trains them on stress reduction methods; understands and analyzes key risk factors, as well as the principles of health promotion in order to prevent cardiovascular, malignant diseases, chronic obstructive pulmonary diseases and diabetes; understands the specifics of the geriatric population and ways to promote health in this population group. |
| Lecturer / Teaching assistant | Regular professor Agima Ljaljević Regular professor Aneta Bošković |
| Methodology | Students work is supervised and realized in the form of lectures, but also other forms of theoretical and practical training, such as presentations, case studies, discussions in small groups. Students are expected to work independently on the preparation of a seminar paper, to read the recommended literature, and to actively participate in all forms of teaching |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | Definition and development of public health; Seminar - Methods of public health sciences; |
| I week exercises | |
| II week lectures | Classifications of public health research achievements;. S - Public health services of different countries; |
| II week exercises | |
| III week lectures | Public health functions S - Ethical principles and directions of public health; |
| III week exercises | |
| IV week lectures | Contemporary public health challenges that bring together various key actors in the field of public health; S - The role of international organizations for the development and implementation of public health; in practice |
| IV week exercises | |
| V week lectures | The importance of developing partnerships and global networks in order to establish a new generation of leaders in public health; S- Health education, as a basic public health strategy |
| V week exercises | |
| VI week lectures | Health care aimed at disease prevention and health preservation; S - Identifying vulnerable population groups and their needs; |
| VI week exercises | |
| VII week lectures | Family arrangement and promotion of individual and community health; S - Socio-economic aspects of health promotion; |
| VII week exercises | |
| VIII week lectures | Determinants (components that condition) behavior. Behavior and health S - Types of behavior that affect health |
| VIII week exercises | |
| IX week lectures | Health education in the service of behavioral modifications that lead to health S - Methods of health education |
| IX week exercises | |
| X week lectures | Contemporary health and education strategies S - Presentation of basic health and education strategies |
| X week exercises | |
| XI week lectures | Campaign preventive activities aimed at health promotion and disease prevention; S - Promotion of breastfeeding and proper nutrition for newborns and infants; |
| XI week exercises | |
| XII week lectures | Health promotion measures aimed at preventing cardiovascular diseases; S - Prevention of sexually transmitted infections; |
| XII week exercises | |
| XIII week lectures | Health promotion measures aimed at preventing diabetes; S - Prevention of addictive diseases; |
| XIII week exercises | |
| XIV week lectures | Health promotion measures aimed at preventing malignant diseases; S - Principles of proper nutrition, physical activity and prevention of obesity; |
| XIV week exercises | |
| XV week lectures | Organization of the application of public health measures and activities in practice; S - Ethical principles and directions of public health; |
| XV week exercises |
| Student workload | In the semester Teaching and final exam: (7 hours) x 16 = 112 hours Necessary preparations before the beginning of the semester (administration, registration, certification): (7 hours) x 2 = 15 hours Total workload for the course: 7 x 30 = 210 hours Additional work for exam preparation in the remedial exam period, including taking the remedial final exam: from 0 to 60 hours (remaining time from the first two items to the total workload for the subject 300 hours) Load structure: 112 hours (classes and final exam) + 15 hours (preparation) + 18 hours (supplementary work) |
| Per week | Per semester |
| 5 credits x 40/30=6 hours and 40 minuts
2 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 4 hour(s) i 40 minuts of independent work, including consultations |
Classes and final exam:
6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work) |
| Student obligations | They regularly attend classes, prepare and present seminar papers and participate in the implementation of classes |
| Consultations | Students have the possibility of daily consultations with subject teachers |
| Literature | Detels R, McEwen J, Beaglehole R, Tanaka H, eds. Oxford Textbook of Public Health, 6th ed., Vol. 1. New York: Oxford University Press 2002. • Merson MH, Black RE, Mills AJ. International Public Health. Diseases, Programs, Systems and Policies. 2nd edition. New York: An Aspen Publication 2003. • Pencheon D, Guest C, Melzer G, Gray M, eds. Oxford handbook of public health practice. Oxford: Oxford University Press 2008. • Tulchinsky TH, Varavikova EA. The New Public Health. New York London: Academic Press 2009. • Centers for Disease Control and Prevention. Public Health Policy. November 9, 2015.www.cdc.gov/stltpublichealth/policy Accessed October12, 2016. • Levi J, Segal LM, Gougelet R, Laurent RS. Investing in Americas Health: A State-by-State Look at Public Health Funding and Key Health Facts. 2015. http://healthyamericans.org/assets/files/TFAH-2015-InvestInAmericaRpt-FINAL.pdf Accessed November14, 2016. • Kaufman NJ, Kindig DA. Public Health vs. Population Health: A Conversation. October 1999.https://uwphi.pophealth.wisc.edu/about/advisory/public-vs-population-health-conversation.pdf Accessed October12, 2016. • Bhattacharya D and Bhatt J. Seven Foundational Principles of Population Health Policy. Popul Health Manag. 2017 Oct 1; 20(5): 383–388. Published online 2017 Oct 1. doi: 10.1089/pop.2016.0148. • Bhattacharya D, Bhatt J. Novel interprofessional collaborations: utilizing medical–legal partnerships to advance population health. In: Bhattacharya D, editor; , Callahan R, editor. , eds. Public health leadership. New York: Taylor and Francis, 2017:41–53 [Google Scholar] |
| Examination methods | Pre-examination point obligations Activity during the lecture 10 Practical teaching 20 Colloquium-i 10 Seminars 10 Attendance continues 10 Exam obligations points Final exam 40 Written exam 10 Oral exam on the 30th |
| Special remarks | |
| Comment |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
Faculty of Medicine / MEDICINE / ZDRAVSTVENA POLITIKA,MENADŽMENT U ZDRAVSTVU
| Course: | ZDRAVSTVENA POLITIKA,MENADŽMENT U ZDRAVSTVU/ |
| Course ID | Course status | Semester | ECTS credits | Lessons (Lessons+Exercises+Laboratory) |
| 11576 | Obavezan | 2 | 5 | 2++0 |
| Programs | MEDICINE |
| Prerequisites | |
| Aims | To provide knowledge to public health professionals about human rights and patient rights, as well as ethical norms and rights of employees in a health institution. The goal is to familiarize students with the ways of managing health institutions, managing financial, material and human resources, as well as the ways of providing and distributing financial resources within the health system. |
| Learning outcomes | It is expected that after passing the exam in this subject, the student will acquire the necessary theoretical knowledge in the field of health and human rights, as well as the skills necessary to apply this knowledge in practice. Understanding these rights is of great importance for all participants in the healthcare system. Developing positive attitudes and behavior in relation to human rights is the basis of successful work on preserving and improving the health of users. In addition, the expected outcomes and competencies are: knowledge and abilities related to human resources management, recognition of the roles and functions of human resources managers, strategic management of human resources in public health, recognition of the importance of learning and training, as well as management and rewarding according to performance. In addition to a good understanding and ability to apply knowledge, participants will develop skills for research and critical analysis of the role of the modern manager and human resource management system, as well as to analyze in writing the effects of policies and procedures on the performance of healthcare organizations. After completing the course, public health professionals will be able to: (a) understand the key concepts of leadership theory, levels and styles of leadership, and the differences between management and leadership; (b) critically analyze the complexity of leadership and motivation of people; (c) understand their role as public health leaders to improve the quality of public health practice; (d) apply relevant concepts of leadership in their own professional workplace and develop leadership skills (mentoring, understanding oneself and followers, lifelong learning); (e) know the challenges of joint leadership; (f) overcome obstacles and facilitate change. Students will gain knowledge about the importance of planning, the differences between operational and strategic planning, the strategic management model, decision-making methods and the differences between group and team work, process and change management models. Students will know how to define the mission, vision, values and principles of the institution, general and specific goals, respecting the guidelines of the SMART technique. They will learn how to analyze the external and internal environment by applying appropriate methods and techniques (PEST, SWOT analysis, stakeholder analysis and stakeholder mapping) techniques. After the activities carried out in the course, students will be able to analyze and apply the health care financing model, as well as to adopt the principles of economy, efficiency and effectiveness of the health care of the population. |
| Lecturer / Teaching assistant | Prof. dr Boban Mugoša, Prof. dr Miodrag Radunović |
| Methodology | Supervised classes consist of lectures and practical sessions (case studies, seminars, discussions and exercises and data processing, group work and preparations for group and individual case presentations) in blended learning - a combination of e-learning and classroom learning. The student is expected to work independently on homework and prepare for each class. |
| Plan and program of work | |
| Preparing week | Preparation and registration of the semester |
| I week lectures | Management in health care, leadership, division, characteristics |
| I week exercises | |
| II week lectures | Health policy and organization of health care |
| II week exercises | |
| III week lectures | Legal framework and health legislation |
| III week exercises | |
| IV week lectures | Ethics in healthcare and patients rights Mission and vision of the healthcare institution |
| IV week exercises | |
| V week lectures | Participants are expected to actively participate (read recommended texts, prepare for lectures, seminars and exercises, and do homework) |
| V week exercises | |
| VI week lectures | Organization and work of health institutions |
| VI week exercises | |
| VII week lectures | Financing of health care, sources of income |
| VII week exercises | |
| VIII week lectures | Health technologies, types, importance, introduction of new health technologies into the system |
| VIII week exercises | |
| IX week lectures | Human resources, planning and needs, education |
| IX week exercises | |
| X week lectures | Current problems in health systems, crisis management |
| X week exercises | |
| XI week lectures | Public health challenges |
| XI week exercises | |
| XII week lectures | Development of health insurance |
| XII week exercises | |
| XIII week lectures | Methods and techniques of external and internal environment analysis (PEST, SWOT analysis, stakeholder analysis, stakeholder mapping) |
| XIII week exercises | |
| XIV week lectures | Basic principles of health economic methods of data collection and analysis |
| XIV week exercises | |
| XV week lectures | Allocation of financial resources in the public health sector |
| XV week exercises |
| Student workload | In the semester Classes and final exam: (6.66 hours) x 16 = 106.56 hours Necessary preparations before the beginning of the semester (administration, registration, certification): (6.66 hours) x 2 = 13.32 hours Total workload for the course: 5 x 30 = 150 hours Load structure: 106.56 hours (teaching and final exam) + 13.32 hours (preparation) + 30 hours (supplementary work) |
| Per week | Per semester |
| 5 credits x 40/30=6 hours and 40 minuts
2 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 4 hour(s) i 40 minuts of independent work, including consultations |
Classes and final exam:
6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work) |
| Student obligations | Students are obliged to attend classes, to work and submit seminar papers |
| Consultations | |
| Literature | 1. Armstrong M. A handbook of management techniques. 3rd edition. London: Kogan Page Limited 2001. 2. UN. Universal Declaration of Human Rights (www.un.org/en/documents/udhr/index.shtml) 3. Donnelly J. Universal human rights in theory and practice (2nd ed.). Ithaca: Cornell University Press, 2003. 4. Longest BB, Rakich JS, Darr K. Managing Health Services Organizations and Systems: Strategic Planning and Marketing. 4th edition. Baltimore, Maryland: Health Professional Press 2004. 5. International Health Regulations (“IHR (2005)”) and related World Health Assembly resolution. (www.who.int/gb/ebwha/pdf_files/WHA58/A58_55-en.pdf), 2005. 6. Shortell SM and Kaluzny AD. Health Care Management Organization. Design and Behavior. 5th edition. USA, Tomson Delmar Learnig 2006. 7. Swayne LE, Duncan WJ, Ginter PM, ed. Strategic Management of Health Care Organizations. 5 th edition. Oxford: Blackwell Publishing 2006. 8. Health and Human Rights. A resource guide for the Open Society Institute and Soros Foundations Network. Equitas, June, 2007. 9. Glaser RG, Traznor RM. Strategic Practice Management. A Patient-Centric Approach. United Kingdom: Plural PublishingInc., 2008. 10. Carpenter MA, Sanders WG. Strategic Management: A Dynamic Perspective, Concepts and Cases. 2nd edition. Upper Saddle River, NJ: Pearson Education International 2009. 11. Forsythe, FP. Encyclopedia of Human Rights. New York: Oxford University Press, 2009. 12. Gruskin, S., Bogescho, D., Ferguson, L.“Rught/based approaches“ to health policies and programmes: Articulation, ambiguities, and assessment. Jounal of Public Health Policy, 31(2), 129-45, 2010 13. Proctor T. Creative Problem Solving for Managers: Developing Skills for Decision Making and Innovation, 3rd edition, Routledge, 2010. 14. Proctor T. Creative Problem Solving for Managers: Developing Skills for Decision Making and Innovation, 3rd edition, Routledge, 2010. |
| Examination methods | Class attendance up to 5 points, homework up to 5 points, presentation of a seminar paper up to 40 points, the final exam is evaluated with a maximum of 50 points; a passing grade is obtained if 50 points and more are cumulatively collected. |
| Special remarks | |
| Comment |
| Grade: | F | E | D | C | B | A |
| Number of points | less than 50 points | greater than or equal to 50 points and less than 60 points | greater than or equal to 60 points and less than 70 points | greater than or equal to 70 points and less than 80 points | greater than or equal to 80 points and less than 90 points | greater than or equal to 90 points |
