University of Montenegro

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE

Course:

ENGLISH LANGUAGE/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
1136	Obavezan	1	3	2+1+0

Programs	PHARMACY
Prerequisites	None.
Aims	Knowledge of Medical English grammatical structures and medical terminology; effective use of English in medical context; ability to read and understand medical literature in English.
Learning outcomes	At the end of this course student will be able to: - predict lecture content and organization from the introduction - follow signposts to lecture organization - choose an appropriate form of lecture notes - recognize the lecturer’s stance and level of confidence/tentativeness - use topic sentences to get an overview of the text - use Internet effectively - speak from notes and summarize - effectively write notes and paraphrase.
Lecturer / Teaching assistant	Prof. dr Nataša Kostić, dr Dragana Čarapić
Methodology	Lectures and seminars, students discussions and presentations; pair, group and individual work in classes

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introducing students to the course syllabus and literature.
I week exercises	Basic medical vocabulary – prefixes and suffixes
II week lectures	Preparing for a lecture
II week exercises	Predicting lecture content
III week lectures	Lecture organization
III week exercises	Choosing the best form of notes
IV week lectures	Achievements in medicine
IV week exercises	Achievements in medicine
V week lectures	Using research questions
V week exercises	Using research questions
VI week lectures	Topic sentences and summarizing
VI week exercises	Topic sentences and summarizing
VII week lectures	Basic principles in medicine
VII week exercises	Basic principles in medicine
VIII week lectures	Using information sources and reporting research findings
VIII week exercises	Using information sources and reporting research findings
IX week lectures	Asking for information and reporting information
IX week exercises	Asking for information and reporting information
X week lectures	Computers in medicine
X week exercises	Computers in medicine – abbreviations and acronyms
XI week lectures	Preparation for reading research – topic development
XI week exercises	Preparation for reading research – topic development
XII week lectures	Analyzing Internet search results and reporting research findings
XII week exercises	Analyzing Internet search results and reporting research findings
XIII week lectures	Causes and effects of disease – describing trends
XIII week exercises	Causes and effects of disease – describing trends
XIV week lectures	Lecture organization – ‘signpost’ language
XIV week exercises	Lecture organization – ‘signpost’ language
XV week lectures	Lecture language; making effective contribution to a seminar
XV week exercises	Lecture language; making effective contribution to a seminar

Student workload	30 lectures + 15 seminars
Per week	Per semester
3 credits x 40/30=4 hours and 0 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 1 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 4 hour(s) i 0 minuts x 16 =64 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 4 hour(s) i 0 minuts x 2 =8 hour(s) i 0 minuts Total workload for the subject: 3 x 30=90 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 18 hour(s) i 0 minuts Workload structure: 64 hour(s) i 0 minuts (cources), 8 hour(s) i 0 minuts (preparation), 18 hour(s) i 0 minuts (additional work)
Student obligations	Regular class attendance, participation in discussions, homework and presentations.
Consultations
Literature	-Patrick Fitzgerald, Marie McCullagh and Ros Wright (2010) English for Medicine in Higher Education Studies. Garnet Edu. (Units 1–5). - Oxford Concise Medical Dictionary (2003), OUP. - Cambridge Advanced Learner’s Dictionary (2013), CUP. - Sofija Mićić: Medicinski rečnik (2007), Zavod za udžbenike, Beograd.
Examination methods	- Presentations: 30 points; - activity in class: 10 points; - final exam: 60 points.
Special remarks	Lectures and seminars are in English.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ANATOMY

Course:

ANATOMY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
1043	Obavezan	1	4	2+1+0

Programs	PHARMACY
Prerequisites
Aims
Learning outcomes
Lecturer / Teaching assistant
Methodology

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures
I week exercises
II week lectures
II week exercises
III week lectures
III week exercises
IV week lectures
IV week exercises
V week lectures
V week exercises
VI week lectures
VI week exercises
VII week lectures
VII week exercises
VIII week lectures
VIII week exercises
IX week lectures
IX week exercises
X week lectures
X week exercises
XI week lectures
XI week exercises
XII week lectures
XII week exercises
XIII week lectures
XIII week exercises
XIV week lectures
XIV week exercises
XV week lectures
XV week exercises

Student workload
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 2 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations
Consultations
Literature
Examination methods
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BIOLOGY WITH HUMAN GENETICS

Course:

BIOLOGY WITH HUMAN GENETICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
647	Obavezan	1	4	2++2

Programs	PHARMACY
Prerequisites	no conditionality
Aims	Through this course, students of Pharmacy will be introduced to the basic settings of contemporary biology and genetics, whose achievements are necessary for the diagnosis and treatment of human diseases. Students will be familiar with the basics of cell biology, molecular biology, developmental biology and genetics, with a focus on important molecular mechanisms that are important to human health. Special emphasis is placed on the fundamental principles of animal biology, including their cellular organization, tissue structure, and role in understanding physiological and genetic processes relevant to humans, as well as the importance of animal models in pharmacy and medicine.
Learning outcomes	After completing one-semester teaching and passing the Biology with Human Genetics exam, a student of Pharmacy will be able to: 1. Describe the structure and function of the hereditary basis of human: nucleic acids, replication, translation and transcription mechanisms, enzymatic regulatory systems, genetic code, chromosome organization, control of gene expression and genetic basis of reproduction; 2. Defines mechanisms for the generation of mutations and their impact on human health, as well as mechanisms for correcting errors in hereditary material; 3. defines the rules of inheritance and describes individual groups of hereditary diseases (chromosomal, monogenic, polygenic) and their behavior on the health of man and his offspring; 4. defines basic cytogenetic methods of cell culture, preparation of karyotype and analyzes the human karyotype using a light microscope; 5. Describes the basic methods of molecular genetics: isolation of DNA, PCR, endonucleases, a gel electrophoresis. 6. describes the application of modern cytogenetic and molecular-genetic techniques in the diagnosis and treatment of hereditary disorders. The student understands the basic morphological and functional characteristics of animal organisms and is able to relate their biological processes to human biology and genetics, recognizing the importance of animal models in pharmaceutical science.
Lecturer / Teaching assistant	Dr Andjelka Scepanovic, assistant professor. Mr. Svetlana Perovic
Methodology	Lectures, exercises, colloquiums

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introductory lecture History and influence of genetics on medicine. A brief overview of the systematics of the animal kingdom and the importance of animal biology for pharmacy and medicine
I week exercises	Introductory lecture, microscopy and coloring techniques
II week lectures	Structure of DNA and RNA. Genetic code. Principles and molecular basis of the flow of genetic information.Basic morphological and functional characteristics of animal cells and tissues.
II week exercises	Prokaryotes and Eukaryotes. Production of microscopic preparation of bacterial cells and single-celled eukaryotes. Microscopic observation of animal cells (epithelial, muscle, and nerve cells).
III week lectures	Regulation of gene expression. Lac operon. Molecular basis and importance of epigenetic mechanisms
III week exercises	Cell propagation at Eukaryotes. Mitosis.
IV week lectures	Molecular mechanisms of gene mutations. Mutagens and carcinogens. Mutagenesis and disease mutations.
IV week exercises	Meiosis and gametogenesis.
V week lectures	Molecular mechanisms of reparation. Recombinating the gene. Genetic maps.
V week exercises	Blood groups in humans
VI week lectures	Techniques for diagnosing gene mutations. Isolation of genomic DNA, PCR and gel electrophoresis
VI week exercises	Test I - Colloquium I from practical classes.
VII week lectures	Colloquium I
VII week exercises	Analysis of the human karyotype.
VIII week lectures	Chromosome and human karyotype. Genetic control of the cell cycle. Disorders.
VIII week exercises	Making a kariogram.
IX week lectures	Legacies and types of inheritance, Gametogenesis.
IX week exercises	Full chromatin -Barr body.
X week lectures	Structural aberrations of chromosomes. Numerical aberrations of chromosomes.
X week exercises	Mono-hybrid crossing.
XI week lectures	Differentiation and gender determination. Genetics develops
XI week exercises	Dihibrid crossing.
XII week lectures	The most common hereditary diseases of man. Genetic testing and ethical problems. Prenatal diagnosis. Clinical genetics and counseling.
XII week exercises	Full-bound inheritance.
XIII week lectures	Aging, Carcinogenesis.Recombinant DNA and its application in medicine. Gene therapy. Famakogenetics.
XIII week exercises	Multiple alleles.
XIV week lectures	Colloquium II
XIV week exercises	Genetics of populations.
XV week lectures	Immunogenetics
XV week exercises	Test II - Colloquium II from practical teaching.

Student workload	Weekly: 4 credits x 40/30 = 5.3 hours. Structure: 1.5 hours of lectures 1.5 hours of laboratory exercises 2.3 hours of independent work including consultation. In the semester: Teaching and final exam: 5.3 hours x 16 = 84.8 hours Necessary preparation before the beginning of the semester (administration, registration and certification): 2 x (8 hours) = 16 hours Total load for subject 4x30 = 120 hours Supplementary work for the preparation of the exam during the corrective test period, including the passing of a correctional exam from 0 to 36 hours (the remaining time from the first two items to the total load for the subjects) Load structure: 84.8 hours (Teaching) + 16 hours (preparation) + 19 , 2 hours (Supplementary work)
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	The student is obliged to attend theoretical classes and exercises, for colloquiums and tests.
Consultations	Every Monday at 15. 00
Literature	1. Guć-Šćekić and D. Radivojević: Manual of Medical Genetics. Faculty of Biology, University of Belgrade 2009. 2. V. Diklic, M. Kosanovic, J. Nikolis, S. Dukić: Biology with Human Genetics. Medical book. 2009. 3. G.M. Cooper and R.E. Hausman: Station, Mol
Examination methods	Two colloquiums of 15 points, two tests on practical exercises of 10 points, and Final exam oral 50 points. A transition score is obtained if cumulatively accumulates at least 50 points.
Special remarks	there are no special indications
Comment	Further information on the subject can be obtained from the subject teacher, the head of the study program and the teaching assistant.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHYSICS

Course:

PHYSICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
1125	Obavezan	1	4	2++2

Programs	PHARMACY
Prerequisites	Non.
Aims	The course of Physics, as a fundamental natural science, prepares students for studying natural phenomena in physics, allows them to adopt the language and methods used in the study of physical phenomena and introduces students to the major concepts and theories which frame our knowledge about material world. The student will be able to easily master the contents of other courses, as well as the principles of modern diagnostic and laboratory instruments (NMR, ultrasound, laser).
Learning outcomes	1. explain essence of processes in the main areas of general Physics; 2. apply mathematical formalism necessary for qualitative and quantitative analysis in these areas; 3. use basic experimental methods and statistically and graphically analyze the obtained measurement results; 4. use scientific and technical literature.
Lecturer / Teaching assistant	professor dr Ivana Pićurić , higher laborant msc Vanja Veljović
Methodology	Lectures, laboratory exercises, studying, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	A detailed presentation of the organization of lectures and exames. Introduction to the Physical Mechanics; Kinematics. Position. Velocity. Acceleration. Motion with constant velocity. Motion with constant acceleration. Projectile motion. Uniform circular motion.
I week exercises	Introduction to the laboratory.
II week lectures	Dynamics. Newtons first law. Inertial reference frames and relative motion. Mass. Newtons second law. Newtons third law. Work done by a constant force. Work as a dot product. Work done by a variable force. Power. Work energy teorem. Kinetic energy. Potential energy. Conservative forces. Conservation of mechanical energy.
II week exercises	Measurement of density of solid and liquid matters.
III week lectures	Fluid mechanics. Density and pressure. Variation of pressure in a fluid at rest. Pascals principle. The hydraulic lever. Archimedes principle. Surface tension. Capilaries. Streamlines and the equation of continuity. Bernoullis equation. Newtons law of viscosity. Reynolds number. Turbulence and chaotic flow. Poiseuilles law.
III week exercises	Measurement of a surface tension with capilaries and microtorsion libre.
IV week lectures	Mechanical waves. Types of waves. The wave equation. Traveling waves. Wave speed on a stretched string. Standing waves. Energy in wave motion. Resonance in the stretched string.
IV week exercises	Measurement of viscosity with Stocks and Ostwalds methods.
V week lectures	Sound waves. Traveling sound waves. The speed of sound. Power and intensity of sound waves. Vibrating air columns.
V week exercises	Measurement of speedof sound with Kundts pipe.
VI week lectures	Temperature and thermal equilibrium. Temperature scales. Thermal expansion. The transfer of heat. Thermal conduction. Convection and radiation. The ideal gas. The first law of thermodynamics. Work done on or by an ideal gas. Cyclical processes.
VI week exercises	Measurement of specific heat capacity of solids.
VII week lectures	First test.
VII week exercises
VIII week lectures	Electrostatics. Electric charge. Coulombs law. The electric field. The electric field of point charge and a ring of charge. Electric field lines. Electric potential energy and potential. Calculating the potential from the field. Potential due to point charge. Equipotential surfaces. Capacitance. Capacitors. The flux of the electric field. Gauss law. A parallel plate capacitor. Capacitors connected in parallel and connected in series. Energy storage in an electric field.
VIII week exercises	Measurement of Omms law in DC circuits.
IX week lectures	Electric current. Current density. Electromotive force. A microscopic view of Ohms law. Resistance and resistivity. Analy sis of circuits. Kirchhoffs first and second laws. Resistors in series and parallel. Energy transfers in an electric circuit.
IX week exercises	Measurement of focal lenght of thin lenses.
X week lectures	The magnetic field. Two parallel currents. The definition of B. Magnetic field lines. Magnetic flux. Ampers law. Calculating the magnetic field due to a current, law of Biot nd Savart. Magnetic field due to a current in a long straight wire and in a circular arc of wire. Magnetic force on a current carrying wire. Magnetic field of a solenoid.
X week exercises	Spectral analysis.
XI week lectures	Faradays law of induction. Lenzs law. Induction and energy transfers. Inductor and inductance. Self induction. Energy stored in magnetic field.
XI week exercises	Preparation for the second test.
XII week lectures	Second test.
XII week exercises
XIII week lectures	Reflection and refraction of light waves. Total internal reflection. Chromatic dispersion. Plane mirrors. Spherical mirrors. Spherical refracting surfaces. Thin lenses. Two lens systems. Simple magnifaying lens. Microscope.
XIII week exercises
XIV week lectures	Nuclear magnetic resonance. X rays. Lasers and laser light.
XIV week exercises
XV week lectures	First test correction.
XV week exercises

Student workload
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations
Consultations
Literature	Halliday, Resnick and Walker: Fundamentals of Physics, volume 1 and 2 (7th edition);
Examination methods	8 laboratory exercises carry 8 points (1 point for each well done,exercise). First test-30 points. Second test-12 points. Final exam-50 points. The student has to collect at least 51 points to obtain a passing grade.
Special remarks	Laboratory exercises are performed in groups of 10 students in the subsequently determined hours on which students will be timely informed.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / INTRODUCTION TO PHARMACY

Course:

INTRODUCTION TO PHARMACY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5089	Obavezan	1	4	3+1+0

Programs	PHARMACY
Prerequisites	None
Aims	Familiarization with the history of pharmacy as a science and profession, understanding the scope of practical work performed by pharmacists and their role within the healthcare system, research, regulatory bodies, and industrial production; recognizing the importance of the development of the Faculty of Pharmacy for society; acquiring knowledge about professional opportunities for pharmacists and the development of the pharmacy profession and its future directions.
Learning outcomes	To introduce the student, at the beginning of their studies, to all the responsibilities, challenges, and the beauty of the pharmaceutical profession. The student recognizes the role of the pharmacist in providing pharmaceutical care and improving the health of patients and the community. The student distinguishes the basic principles of social pharmacy and applies them within the context of the healthcare system. The student demonstrates the ability to communicate with patients at a basic level, in accordance with the principles of ethics, professional responsibility, and health literacy. The student explains the importance of collaboration between pharmacists and other healthcare professionals in order to improve treatment outcomes.
Lecturer / Teaching assistant	Zorica Potpara, PhD, Assoc. Prof
Methodology	Lectures, practical sessions (workshops), seminars, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	History of the establishment of pharmacy and Its separation from medicine
I week exercises	Discussions within the group about the development of pharmacy throughout history
II week lectures	Herbal treatment - traditional methods of treatment in our country and the world
II week exercises	Animation of topics about treatment in the medieval period
III week lectures	Comparison of the work of pharmacists then and now, making the first drugs within the pharmacy
III week exercises	Presentation of cases of pharmacies then and now
IV week lectures	The emergence of the first factories and industrial production of drugs over time, both in our country and worldwide
IV week exercises	Production of the first drugs that marked the beginning of industrial pharmacy
V week lectures	Drugs that were significant for the development of pharmacy and for human health
V week exercises	Presentation of cases of drugs significant for the development of pharmacy
VI week lectures	Good pharmacy practice rules. Test
VI week exercises	Discussion of test results with a review of knowledge and skills supplementation
VII week lectures	Health and disease - basic concepts, patient behavior
VII week exercises	Animation related to communication between healthcare professionals, pharmacists, and patients
VIII week lectures	Types of mandatory healthcare
VIII week exercises	Familiarization with specific legal regulations
IX week lectures	Over-the-counter drugs - self-medication
IX week exercises	Examples of over-the-counter drugs - self-medication
X week lectures	Rules and types of communication with patients, healthcare professionals, and other collaborators
X week exercises	Good communication patient-pharmacist
XI week lectures	The Role of the Pharmacist in Pharmaceutical Care and Community Health Improvement
XI week exercises	The Importance of a Patient-Centered Approach
XII week lectures	Basic Principles of Pharmaceutical Care: Assessment, Planning, Intervention, and Evaluation
XII week exercises	Short Simulation of Communication with a Patient with Low Health Literacy
XIII week lectures	Promotion of Healthy Lifestyles and Disease Prevention
XIII week exercises	The Pharmacist as an Educator and Public Health Promoter
XIV week lectures	Ethical Principles in Working with Patients. Professional Responsibility and Confidentiality of Information
XIV week exercises	Discussion: The Pharmacist’s Attitude Toward Patients from Vulnerable Groups
XV week lectures	Introduction to the Healthcare System of Montenegro
XV week exercises	Introduction to the Healthcare System of Montenegro

Student workload	Weekly 4 credits x 40/30 = 5.33 hours. Structure: 2 hours of lectures, 1 hour of exercises, 1 hour of seminar, 0.66 hours of independent student work. Teaching and final exam: (5.33 hours) x 16 = 85.28 hours. Necessary preparations before the beginning of the semester (administration, enrollment, verification): (5.33 hours) x 2 = 10.66 hours. Total workload for the course: 4 x 30 = 120 hours. Workload structure: 85.28 hours (classes and final exam) + 10.66 hours (preparation) + 24 hours (additional work)
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance at lectures and practical classes. Continuous acquisition of knowledge and skills.
Consultations	Additional information about the course can be obtained from the course teacher.
Literature	1.Smith MC,Wertheimer AI.Social and Behavioural Ascpects of Pharmaceutical Care. New York,London:Pharm. preoducts Press, 1996. 2.Anderson S.ed.Making Medicines-A brief History of pharmacy and pharmaceuticals,1 st ed.Pharmaceu¬tical Press,2005. 3.Schmilz R.,Geschichte der Pharmazie band II,Govi-Verlag Pharmazeutisher Verlag GmbH,Eschborn,2005. 4.Remington:Science and Practice of Pharmacy,Lippincott Williams and Wilkins,20thedition(2000). 5.Meldrum H.lnterpersonal communication in harmaceutical care.Pharmaceutical roducts Press,1994
Examination methods	Pre-examination requirements: 50 points; Attendance at lectures (0-5) points; Exercise activity and exercise preparation (0-15); Test from the theoretical part of the material (0-10) points; Test from the practical part of the material (0-20) points. Final exam: 0-50 points
Special remarks	No
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / MATHEMATICS

Course:

MATHEMATICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5090	Obavezan	1	4	2+2+0

Programs	PHARMACY
Prerequisites	No
Aims	Adoption of basic mathematical concepts with the idea of later applied in other disciplines
Learning outcomes	1. describe the Cartesian and polar coordinate systems in plane and space and know how to describe the basic geometry concepts in coordinate systems (points, lines, circles, spheres, plane in space); 2. recognise systems of linear equations and know how to record the system in a matrix form; 3. know the definition of limits of sequences and functions, and define the interpretation of derivatives (geometric and physical interpretation) and integrals (geometric interpretation); 4. understand and describe the specific geometric objects in the coordinate system and assess the advantages and disadvantages of the method of coordinates; 5. know the basic operations with matrices, calculate derivatives and, by using derivatives, determine the largest and smallest value of a function, as well as solve some specific tasks; 6. determine some properties of geometric objects using the method of coordinates, solve systems of linear equations by using various methods, use derivatives to solve some practical tasks related to the largest and smallest value of a function and calculate the surface area of a plane figure by using integrals; 7. determine some properties of geometric figures and solids, the relative position of the basic geometric objects, analyse systems of linear equations, and know how to calculate the surface area and volume of a plane figure or a solid; 8. know how to solve complex geometric tasks by using the method of coordinates, how to graphically represent a function, after previously determining its properties using limit values and derivatives, how to determine all properties of the specific systems of linear equations.
Lecturer / Teaching assistant	Prof. dr Milojica Jaćimović, mr Dušica Slović
Methodology	Lectures, seminars, consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Matrices. Matrix algebra. Systems of linear equalities.
I week exercises	Matrices. Matrix algebra. Systems of linear equalities.
II week lectures	Determinants. Cramer s formulas. Gauss algorithm.
II week exercises	Determinants. Cramer s formulas. Gauss algorithm.
III week lectures	Vectors algebra. Equations of line in plane.
III week exercises	Vectors algebra. Equations of line in plane.
IV week lectures	Equations of line in space. Equations of plane in space.
IV week exercises	Equations of line in space. Equations of plane in space.
V week lectures	Elementary functions and their properties.
V week exercises	Elementary functions and their properties.
VI week lectures	Sequences. Limit of sequences. Examples.
VI week exercises	Sequences. Limit of sequences. Examples.
VII week lectures	Limit of functions. Continuity. Examples.
VII week exercises	Limit of functions. Continuity. Examples.
VIII week lectures	Test.
VIII week exercises	Test.
IX week lectures	Derivative of functions. Geometric and physical meaning of derivative. Examples.
IX week exercises	Derivative of functions. Geometrical and physical meaning of derivative. Examples.
X week lectures	Monotonicity and convexity of functions.
X week exercises	Monotonicity and convexity of functions.
XI week lectures	Graph of the functions. Examples.
XI week exercises	Graph of the functions. Examples. Correctional test.
XII week lectures	Indefinite integral. Partial integration and change of variables.
XII week exercises	Indefinite integral. Partial integration and change of variables.
XIII week lectures	Definite integral. Newton-Leibniz formula.
XIII week exercises	Definite integral. Newton-Leibniz formula.
XIV week lectures	Applications of definite integral. Examples.
XIV week exercises	Applications of definite integral. Examples.
XV week lectures	Differential equations. Simple examples.
XV week exercises	Differential equations. Simple examples.

Student workload	2 classes of lecturs, 2 classes of seminars, 2 hours and 20 minutes of individual work
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Attendance at lectures and seminars, solving the test and the final exam.
Consultations	As agreed with the professor or teaching assistant.
Literature	1. D. Kečkić, S. Nikčević, Matematika, Farmaceutski fakultet u Beogradu, 2005; 2. M. Jaćimović, P. Stanišić, Matematika, Podgorica, 2001
Examination methods	Test 40 points, Final exam 60 points. Grading scale: F (below 51 points), E (51-60 points), D (61-70 points), C (71-80 points), B (81-90 points), E (91-100 points)
Special remarks	In the lectures are not given proof of the theorem, but only formulation and applications, with the selected simple examples.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ORGANIC CHEMISTRY I

Course:

ORGANIC CHEMISTRY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5093	Obavezan	1	4	3++0

Programs	PHARMACY
Prerequisites	No prerequisites
Aims	The place, role and importance of organic chemistry in the modern pharmaceutical industry and everyday life. Basic knowledge of classification, structure, properties and mechanisms of reactions of organic compounds. Relating the structure and functions of the organic molecules.
Learning outcomes	1. know the ways of bonding, types of hybridisation and electronic effects in organic compounds; 2. classify organic compounds according to their functional groups and distinguish the basic classes of organic compounds; 3. describe and explain the physical and chemical properties and reactivity of organic compounds on the basis of their structure; 4. explain the phenomenon of isomerism in organic molecules, distinguish the various types of isomerism and explain them; 5. identify types of organic reactions and apply the notation method used for presenting the reaction mechanisms; 6. analyse the basic reaction mechanisms and explain the structural and electronic properties of the reactants which affect them.
Lecturer / Teaching assistant
Methodology	Lectures. Consultations. Control tests.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction-a brief history of organic chemistry. The properties of chemical bonds in organic compounds. The structure of carbon atoms of sp3-hybridization, molecular orbitals.
I week exercises
II week lectures	Electronic effect organic molekules. The functional groups. Classification of organic compounds.
II week exercises
III week lectures	Saturated hydrocarbons - alkanes and cycloalkanes. The composition, structure, nomenclature, isomerism, physical and chemical properties. A special emphasis on radical substitution.
III week exercises
IV week lectures	Unsaturated hydrocarbons - alkenes, alkynes, alkadiene. The composition, structure, nomenclature, isomerism, obtained. Delocalisation and reactivity. Electrophilic addition. Test I.
IV week exercises
V week lectures	Aromatic hydrocarbons - benzene and its derivatives. Structure, reactivity and importance of aromatic compounds. A special emphasis on electrophilic substitution.
V week exercises
VI week lectures	Halogenated hydrocarbons - alkyl-, alkenyl-, and aryl derivatives. Characteristics and applications. Mechanisms SN-reaction. 1. Coloquium.
VI week exercises
VII week lectures	Alcohols (mono-, di-, tri- and polyhydric alcohols). Structure, nomenclature, isomerism, physical and chemical properties, amphoterism.
VII week exercises
VIII week lectures	Phenols and benzoquinones - nomenclature, characteristics and factors affecting their acidity and reactivity. A special emphasis on electrophilic substitution. Ethers, mercaptans and thioethers. Properties and significance.
VIII week exercises
IX week lectures	Carbonyl compounds - aldehydes and ketones. The composition, structure, nomenclature and reactivity. The mechanism of nucleophilic addition to aldehydes and ketones.
IX week exercises
X week lectures	Keto-enol isomerism. α, β-unsaturated carbonyl compounds. β-dicarbonyl compounds. Enolate ions and the formation of C-C bonds. Test II.
X week exercises
XI week lectures	Carboxylic acids - structure, nomenclature and properties. The difference in reactivity among aromatic and aliphatic acids. A special review of the acyl substitution.
XI week exercises
XII week lectures	The carboxylic acid derivatives - classification, nomenclature and importance. Particular reference to the α-halo and α-hydroxy acid. 2. Coloquium.
XII week exercises
XIII week lectures	Amines - composition and structure. The difference between the aliphatic and aromatic amines.
XIII week exercises
XIV week lectures	Amino acids - composition, structure, nomenclature, properties and significance. A special review of the peptide bond and the synthesis of dipeptide. Correctional Coloquium.
XIV week exercises
XV week lectures	Preparation for final exam
XV week exercises

Student workload	A week: 4 credits x 40/30 = 5 hours and 20 min Struktura: 3 hours of lectures 2 hours and 20 of student work, including consultations. During the semester Teaching and the final exam: (5 hours and 20 min) x 16 = 85 hours and 20 min Necessary preparation (before semester administration, enrollment and verification): (5 hours and 20 min) x 2 = 10 hours and 40 min Total hours for the course: 4 x 30 = 120 hours Additional work: to prepare the corrective final exam, including the exam taking 0 to 24 hours (the remaining time of the first two items to the total work hours for the subject of 120 hours). Structure: 85 hours and 20 min (lecture) + 10 hours and 40 min (preparation) + 24 hours (additional work).
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 2 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend lectures, do control tests and coloquiums.
Consultations	Monday: 9-11am, Thursday: 9-11am.
Literature	1. Organic chemistry, K.P.Vollhardt and N.E.Schore 2 .S. Arsenijević, Organska hemija, Naučna knjiga, Beograd. 3. Organic chemistry, R. Morison and R. Boyd 4. Organic chemistry, A. Taylor
Examination methods	Presence of lectures: 0 – 8 pts Control tests: 0 – 12 pts ( 2 x 6 pts) Coloquiums: 0 – 30 pts ( 2 x 15 pts) Final exam: 0 – 50 pts
Special remarks	-
Comment	-

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / GENERAL AND INORGANIC CHEMISTRY

Course:

GENERAL AND INORGANIC CHEMISTRY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5092	Obavezan	1	7	3++3

Programs	PHARMACY
Prerequisites	No requirements for reporting and listening to cases
Aims	By studying this course, students acquire basic knowledge in general and neo-oganic chemistry, get to know the basic chemical phenomena, laws and principles, get to know the chemical elements of PSE, their important compounds, properties and applications with special emphasis on pharmaceutically significant compounds.
Learning outcomes	Learning outcomes (aligned with outcomes for the study programme): Know the basic chemical laws, phenomena and concepts - Uses basic stoichiometric account - Connects the laws in the periodic table of elements with the position of the element in PSE, atom structure and chemical bond -Explains solutions, chemical reactions and their physicochemical processes and rules including speed and balance - Applies the acquired knowledge of coordination units with a special emphasis on pharmaceutically important coordination compounds - Classifies the basic types of inorganic compounds according to their properties structure and Applying
Lecturer / Teaching assistant	Prof. dr Željko Jaćimović Msc Mia Stanković
Methodology	Lecture and exercises (laboratory and computational), independent preparation of homework. Additional, preparatory dates for passing exams and colloquiums. Consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Formal reception of students. Introducing students to teaching, homework, colloquiums, final exam, Division of Information for Students and work plan Basic chemical concepts and laws
I week exercises	Getting acquainted with working in a chemical laboratory Basic laboratory supplies and operations
II week lectures	Gas laws, stoichiometry, chemical equations and calculations
II week exercises	Stoichiometric calculations
III week lectures	The periodic table, the structure of the atom and the chemical bond
III week exercises	Mixture, Division I homework
IV week lectures	Solutions
IV week exercises	Solutions, Surrender I Homework
V week lectures	The speed of the chemical reaction
V week exercises	The speed of the chemical reaction
VI week lectures	Chemical equilibrium, homogeneous and heterogeneous systems
VI week exercises	Chemical equilibrium, homogeneous and heterogeneous systems
VII week lectures	Oxido-reduction reactions
VII week exercises	Oxido-reduction reactions, Division II of homework
VIII week lectures	Complex compounds
VIII week exercises	Complex compounds, Surrender ii of homework
IX week lectures	Pharmaceutically significant complex compounds
IX week exercises	HCl titration curve with NaOH
X week lectures	PSE, position and characteristics of chemical elements, hydrogen
X week exercises	Hydrolysis of salts
XI week lectures	Chemistry of nonmetals, review of elements
XI week exercises	As, Sb, Bi, Division III homework
XII week lectures	Non-metal compounds with oxygen and hydrogen, oxy acids
XII week exercises	Mn, Cr, Fe, Co, Ni, Submission III homework. Laboratory TEST
XIII week lectures	Metal Chemistry, Element Overview, Binary Compounds
XIII week exercises	Important cations and anions and their qualitative proof
XIV week lectures	Properties and solubility of oxides and hydroxides
XIV week exercises	Colloquium, compensation for undone exercises
XV week lectures	Preparartion final exam
XV week exercises	Remedial colloquium

Student workload	Per week 9 credits x 40/30 = 12 hours 5.15 hours of lectures and exercises 6.45 hours of self-study
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend classes, do all laboratory exercises provided for in the plan.
Consultations
Literature	1.Filipović, S.Lipanović General and inorganic chemistry; D.Poleti General Chemistry Part II; 2. M.Dragović, M.Popović, S.Stević, V.Šćepanović General Chemistry Part I; 3. Lj.Bogunović, O.Leko, M.Popović, S.Stević, O.Ćuković, J.Šašić Practicum of General Chemistry Part II 4. V.Češljević, V.Leovac, E.Ivegeš Practicum of Inorganic Chemistry; 5. S.Nešić, R.Bulajić, A.Kostić, S.Marinković Practicum of General Chemistry with qualitative analysis; 6. M. Sikirica, Stehiometry, Školska knjiga, Zagreb 1989.
Examination methods	Forms of knowledge testing and assessment: Forms of knowledge testing and assessment: - 3 homework (6 points) - Activity on exercises and submit reports (4 points) - Test from laboratory exercises (10 points) - Colloquium (30 points) - Final exam (50 points) The exam is passed if you cumulatively collect 50 points.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / METHODOLOGY OF SCIENTIFIC WORK

Course:

METHODOLOGY OF SCIENTIFIC WORK/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
13250	Obavezan	10	3	2++0

Programs	PHARMACY
Prerequisites	None.
Aims	The main objective of the course Methodology of Scientific Research is to equip students with the skills necessary to independently design research in the field of healthcare, conduct research, write papers for scientific journals, and present the results of their scientific work orally. Additionally, the course aims to develop students research skills through digital processing, statistical analysis, and critical evaluation of scientific literature, using modern information technologies.
Learning outcomes	1. Understand the need for a systematic approach to scientific research work. 2. Accept the principles of scientific research work in medicine and especially in pharmacy. 3. Get trained for independent conception of scientific research work. 4. Accept the principles of teamwork. 5. Acquire the necessary knowledge in the oral presentation of works. 6. Acquire the necessary knowledge in submitting papers to journals and the review process.
Lecturer / Teaching assistant	Dušan Mustur, Assist. Prof., MD, MSc, PhD
Methodology	1 class of lecture + 1 class of seminar

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction. Science, scientific activity and research. General methodology of scientific research.
I week exercises
II week lectures	Scientific methods.
II week exercises
III week lectures	Technology of Scientific Research
III week exercises
IV week lectures	Identifying a scientific problem and its formulation. Formulating a hypothesis that explains the phenomenon.
IV week exercises
V week lectures	Collecting, studying, and organizing literary sources and scientific information. Searching and using scientific databases (PubMed, Cochrane, Scopus).
V week exercises
VI week lectures	Types of scientific publications: primary, secondary, and tertiary. Electronic data processing and presentation of results (graphs, tables).
VI week exercises
VII week lectures	Designing surveys and processing data through online platforms (Google Forms, SurveyMonkey).
VII week exercises
VIII week lectures	Preparing the structure or composition of a scientific paper.
VIII week exercises
IX week lectures	Methodology of Scientific Research in Medicine
IX week exercises
X week lectures	Basics of Research Ethics in Medicine
X week exercises
XI week lectures	Multidisciplinary Nature of Research in Medicine
XI week exercises
XII week lectures	Methodological Aspects of Experimental Research in Medicine
XII week exercises
XIII week lectures	Methodological Aspects of Clinical Research in Medicine
XIII week exercises
XIV week lectures	The Relationship Between Research and Practice in Medical Sciences
XIV week exercises
XV week lectures	Evidence-Based Medicine
XV week exercises

Student workload
Per week	Per semester
3 credits x 40/30=4 hours and 0 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 4 hour(s) i 0 minuts x 16 =64 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 4 hour(s) i 0 minuts x 2 =8 hour(s) i 0 minuts Total workload for the subject: 3 x 30=90 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 18 hour(s) i 0 minuts Workload structure: 64 hour(s) i 0 minuts (cources), 8 hour(s) i 0 minuts (preparation), 18 hour(s) i 0 minuts (additional work)
Student obligations	Attending classes regularly, writing a seminar paper, passing two colloquiums and a final exam (test).
Consultations	Regular consultations are scheduled by agreement with the students.
Literature	Lalatović Z. Metodologija naučno-istraživačkog rada sa osnovama statistike. Available from URL: http://www.fms-tivat.me/predavanja4god/Metodologija_naucno_istrazivackog_rada_ZL.pdf.
Examination methods	Regular class attendance: (0–10) points Seminar paper: (0–20) points Colloquium: (0–20) points Final exam: (test) 50 points
Special remarks	None.
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / GRADUATION PAPER

Course:

GRADUATION PAPER/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
2149	Obavezan	10	10	1++0

Programs	PHARMACY
Prerequisites	All courses required by the study program have been passed.
Aims	The aim of the course is for the student to demonstrate the ability to conduct independent professional and/or research work in the field of pharmacy, through the integration of knowledge acquired during the studies, the application of scientific research methods, and the ability to systematically present findings in both written and oral form.
Learning outcomes	After the defense of the final thesis, the student is able to: Formulate a research question, define objectives and hypotheses; Select and apply an appropriate research methodology while respecting ethical principles; Collect, analyze, and statistically process data; Critically evaluate the literature and integrate relevant sources; Write the thesis in accordance with academic and professional standards; Prepare and deliver a clear, well-structured presentation of the work; Interpret and discuss the results professionally and responsibly; Establish a foundation for further scientific research and professional work.
Lecturer / Teaching assistant
Methodology	In accordance with the topic of the Final Thesis, the research methods include: Descriptive method (literature review) Experimental methods Retrospective and prospective analyses Statistical methods Case studies

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	The Final Thesis represents an independent professional or research work by the student, in which the knowledge acquired during pharmacy studies is applied, particularly in the field of scientific research methodology. During the tenth semester, the student selects the area and topic of the thesis in agreement with the mentor. After conducting preliminary research or writing the theoretical part of the thesis, the student prepares the final paper in written form, which includes the following chapters: Introduction, Objectives, Methodology, Results and Discussion, Conclusion, and References. Once the thesis is completed and approved by the mentor, an oral defense is scheduled. The defense takes place before a three-member committee consisting of: the committee chair, the mentor, and one additional member. The student briefly presents the main elements of the thesis and then answers questions from the committee members. Upon completion of the oral defense, the committee members jointly propose a final grade, which is based on both the quality of the written thesis and the student’s performance during the defense. The process of submitting the final thesis is defined by the Rulebook on the Preparation of Final Theses at undergraduate, basic academic, and integrated studies at the Faculty of Medicine in Podgorica. More detailed instructions are available on the Faculty’s website.
I week exercises
II week lectures
II week exercises
III week lectures
III week exercises
IV week lectures
IV week exercises
V week lectures
V week exercises
VI week lectures
VI week exercises
VII week lectures
VII week exercises
VIII week lectures
VIII week exercises
IX week lectures
IX week exercises
X week lectures
X week exercises
XI week lectures
XI week exercises
XII week lectures
XII week exercises
XIII week lectures
XIII week exercises
XIV week lectures
XIV week exercises
XV week lectures
XV week exercises

Student workload
Per week	Per semester
10 credits x 40/30=13 hours and 20 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 12 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 13 hour(s) i 20 minuts x 16 =213 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 13 hour(s) i 20 minuts x 2 =26 hour(s) i 40 minuts Total workload for the subject: 10 x 30=300 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 60 hour(s) i 0 minuts Workload structure: 213 hour(s) i 20 minuts (cources), 26 hour(s) i 40 minuts (preparation), 60 hour(s) i 0 minuts (additional work)
Student obligations	The student is required to regularly attend consultations with the assigned mentor within the scheduled hours.
Consultations
Literature	Marušić M, ed. Introduction to Scientific Research in Medicine, 6th ed. Medicinska naklada, Zagreb, 2019. Suggested literature in the field and subject of the Final Thesis is to be selected in collaboration with the mentor and committee members, depending on the chosen topic of the thesis (including domestic and international medical and nursing journals, textbooks, books, defended theses, and other relevant literature related to the thesis topic).
Examination methods	Thesis Defense The evaluation includes the quality of the final thesis and its public defense. The quality of the written thesis is assessed with 0–50 points, and the public presentation of the thesis with 0–50 points. A successfully defended thesis requires a cumulative score of 50 points or more.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PROFESSINAL PRACTICE

Course:

PROFESSINAL PRACTICE/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
13251	Obavezan	10	17	+40+0

Programs	PHARMACY
Prerequisites
Aims	Preparing students for the performance of the pharmaceutical service after obtaining a college diploma
Learning outcomes	1. apply the knowledge gained in the ordering, receipt and storage of medicines and medical supplies; 2. use acquired knowledge in the development of major and galenic drugs, issuing of finished medicines and other medical supplies; 3. identify and adopt strategies to resolve problems related to habitual drug usage; 4. know the regulations on registration, method of use and side effects of medicines; 5. use the acquired knowledge in communication with patients, experts and the general public.
Lecturer / Teaching assistant	Prof. dr Vera Dabanović
Methodology	Visiting the institutions engaged in the pharmaceutical business and meeting with pharmaceutical operations carried out in institutions which conducts professional practice

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures
I week exercises	Wholesale
II week lectures
II week exercises	Introductory remarks on the work conducted by wholesaler
III week lectures
III week exercises	An overview of legal regulations related to the operations being carried out by wholesalers , to introduce students to the method of storage and distribution of medicines to health institutions
IV week lectures
IV week exercises	City Pharmacy
V week lectures
V week exercises	To familiarize students with the structure of pharmacies and pharmacy practice that is done in it , the display of the electronic structure and the system of issuing prescriptions drugs that are going to load FZ , exploring the way of the issuance of para
VI week lectures
VI week exercises	Production of drugs
VII week lectures
VII week exercises	Visit to the industrial plants for the production of drugs
VIII week lectures
VIII week exercises	Introduction to the legal regulations and quality management system
IX week lectures
IX week exercises	Visit to the laboratory for analysis and control of drugs and getting to know the way of working in the said laboratories
X week lectures
X week exercises	The hospital pharmacy
XI week lectures
XI week exercises	Introduction to the pharmaceutical activities carried out in the hospital pharmacy
XII week lectures
XII week exercises	Preparation of liquid and semi-solid pharmaceutical forms that are used in the treatment of hospitalized patients
XIII week lectures
XIII week exercises	Institute for Medicines and Medical Devices
XIV week lectures
XIV week exercises	Introducing the system of work of the Institute for Pharmaceuticals and Medical Devices
XV week lectures
XV week exercises	Overview of legislation applied to drug registration

Student workload
Per week	Per semester
17 credits x 40/30=22 hours and 40 minuts 0 sat(a) theoretical classes 0 sat(a) practical classes 40 excercises -18 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 22 hour(s) i 40 minuts x 16 =362 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 22 hour(s) i 40 minuts x 2 =45 hour(s) i 20 minuts Total workload for the subject: 17 x 30=510 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 102 hour(s) i 0 minuts Workload structure: 362 hour(s) i 40 minuts (cources), 45 hour(s) i 20 minuts (preparation), 102 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of professional practice in these institutions
Consultations	Professional staff hired to perform professional practice in these institutions hold consultations with students in the term that is defined at the beginning of professional practice .
Literature	All relevant literature used by the staff in performing their tasks pharmaceutical activities in these institutions , shall be made available to students during a training
Examination methods	The marks give descriptive, passed or failed to pass the professional practice
Special remarks	Professional practice must be carried out according to the plan and program for the performance of professional practice
Comment	Additional information can be given by the professor

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / UNDERGRADUATE PRACTICE

Course:

UNDERGRADUATE PRACTICE/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7643	Obavezan	10	20	0+30+0

Programs	PHARMACY
Prerequisites
Aims	Preparing students for the performance of the pharmaceutical service after obtaining a college diploma
Learning outcomes	1. apply the knowledge gained in the ordering, receipt and storage of medicines and medical supplies; 2. use acquired knowledge in the development of major and galenic drugs, issuing of finished medicines and other medical supplies; 3. identify and adopt strategies to resolve problems related to habitual drug usage; 4. know the regulations on registration, method of use and side effects of medicines; 5. use the acquired knowledge in communication with patients, experts and the general public.
Lecturer / Teaching assistant	Prof. dr Zorica Potpara,
Methodology	Visiting the institutions engaged in the pharmaceutical business and meeting with pharmaceutical operations carried out in institutions which conducts professional practice

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures
I week exercises	Wholesale
II week lectures
II week exercises	Introductory remarks on the work conducted by wholesaler
III week lectures
III week exercises	An overview of legal regulations related to the operations being carried out by wholesalers , to introduce students to the method of storage and distribution of medicines to health institutions
IV week lectures
IV week exercises	City Pharmacy
V week lectures
V week exercises	To familiarize students with the structure of pharmacies and pharmacy practice that is done in it , the display of the electronic structure and the system of issuing prescriptions drugs that are going to load FZ , exploring the way of the issuance of para
VI week lectures
VI week exercises	Production of drugs
VII week lectures
VII week exercises	Visit to the industrial plants for the production of drugs
VIII week lectures
VIII week exercises	Introduction to the legal regulations and quality management system
IX week lectures
IX week exercises	Visit to the laboratory for analysis and control of drugs and getting to know the way of working in the said laboratories
X week lectures
X week exercises	The hospital pharmacy
XI week lectures
XI week exercises	Introduction to the pharmaceutical activities carried out in the hospital pharmacy
XII week lectures
XII week exercises	Preparation of liquid and semi-solid pharmaceutical forms that are used in the treatment of hospitalized patients
XIII week lectures
XIII week exercises	The Agency for Medicines and Medical Devices
XIV week lectures
XIV week exercises	Introducing the system of work of the Agency for Pharmaceuticals and Medical Devices
XV week lectures
XV week exercises	Overview of legislation applied to drug registration

Student workload	Total hours : 336 for 42 days ( 8 weeks and 2 days)
Per week	Per semester
20 credits x 40/30=26 hours and 40 minuts 0 sat(a) theoretical classes 0 sat(a) practical classes 30 excercises -4 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 26 hour(s) i 40 minuts x 16 =426 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 26 hour(s) i 40 minuts x 2 =53 hour(s) i 20 minuts Total workload for the subject: 20 x 30=600 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 120 hour(s) i 0 minuts Workload structure: 426 hour(s) i 40 minuts (cources), 53 hour(s) i 20 minuts (preparation), 120 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of professional practice in these institutions
Consultations	Professional staff hired to perform professional practice in these institutions hold consultations with students in the term that is defined at the beginning of professional practice .
Literature	All relevant literature used by the staff in performing their tasks pharmaceutical activities in these institutions , shall be made available to students during a training
Examination methods	The marks give descriptive, passed or failed to pass the professional practice
Special remarks	Professional practice must be carried out according to the plan and program for the performance of professional practice
Comment	Additional information can be given by the professor

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE

Course:

ENGLISH LANGUAGE/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
10732	Obavezan	2	2	2+1+0

Programs	PHARMACY
Prerequisites	None
Aims	Knowledge of Medical English grammatical structures and medical terminology; effective use of English in medical context; ability to read and understand medical literature in English.
Learning outcomes	At the end of this course student will be able to: - use research questions to focus on relevant information - recognize the writer’s stance and level of confidence/tentativeness - make effective contributions to a seminar - ask for clarification – formulating questions - report findings from other sources – avoiding plagiarism.
Lecturer / Teaching assistant	Prof. dr Nataša Kostić, dr Dragana Čarapić
Methodology	Lectures and seminars.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Biology, biochemistry and pharmacology
I week exercises	Biology, biochemistry and pharmacology
II week lectures	Identifying subject-verb-object in long sentences
II week exercises	Subject-verb-object in long sentences and paraphrasing
III week lectures	Understanding and writing complex sentences
III week exercises	Understanding and writing complex sentences
IV week lectures	Clinical setting: acute care
IV week exercises	Clinical setting: acute care
V week lectures	Sequencing information in sentences
V week exercises	Sequencing information in sentences: fixed phrases
VI week lectures	Giving sentences a special focus; making effective contribution to a seminar
VI week exercises	Giving sentences a special focus; making effective contribution to a seminar
VII week lectures	Clinical setting: primary care
VII week exercises	Essay types; complex sentences within passives
VIII week lectures	Passives in dependent clauses; essay plans
VIII week exercises	Passives in dependent clauses; essay plans
IX week lectures	Writing complex sentences
IX week exercises	Writing essay plans and writing essays
X week lectures	Non-clinical setting: public health
X week exercises	Public health: medical terms
XI week lectures	Using the Cornell note-taking system
XI week exercises	Using the Cornell note-taking system
XII week lectures	Recognizing digression; writing source references
XII week exercises	Recognizing digression; writing source references
XIII week lectures	Evidence-based medicine
XIII week exercises	Evidence-based medicine
XIV week lectures	Identifying stance and level of confidence; inferring implicit ideas
XIV week exercises	Identifying stance and level of confidence; inferring implicit ideas
XV week lectures	Situation-problem-solution-evaluation essays
XV week exercises	Situation-problem-solution-evaluation essays

Student workload	Per week: 3 credits x 40/30=4 hours 1,5 hours of theoretical classes 45 minutes of practical classes 1 hour and 45 minutes of independent work, including consultations. Classes and final exam: 4 hours x 16 =64 hours Necessary preparation before the beginning of the semester (administration, registration, certification): 4 hours x 2 =8 hours Total workload for the subject: 3 x 30=90 hours Additional work for exam preparation in the preparing exam period, including taking the remedial exam (remaining time from the first two items to the total load for the item) - 18 hours Workload structure: 64 hours (courses), 8 hours (preparation), 18 hours (additional work)
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises -1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Regular class attendance, participation in discussions, homework and presentations.
Consultations	kostic@ucg.ac.me
Literature	-Patrick Fitzgerald, Marie McCullagh and Ros Wright (2010) English for Medicine in Higher Education Studies. Garnet Edu. (Units 6–10). - Oxford Concise Medical Dictionary (2003), OUP. - Cambridge Advanced Learner’s Dictionary (2013), CUP.
Examination methods	- Presentations: 30 points; - activity in class: 10 points; - final exam: 60 points
Special remarks	-
Comment	Lectures and seminars are in English.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / HYSTOLOGY

Course:

HYSTOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
2003	Obavezan	2	3	1+1+0

Programs	PHARMACY
Prerequisites
Aims
Learning outcomes
Lecturer / Teaching assistant
Methodology

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures
I week exercises
II week lectures
II week exercises
III week lectures
III week exercises
IV week lectures
IV week exercises
V week lectures
V week exercises
VI week lectures
VI week exercises
VII week lectures
VII week exercises
VIII week lectures
VIII week exercises
IX week lectures
IX week exercises
X week lectures
X week exercises
XI week lectures
XI week exercises
XII week lectures
XII week exercises
XIII week lectures
XIII week exercises
XIV week lectures
XIV week exercises
XV week lectures
XV week exercises

Student workload
Per week	Per semester
3 credits x 40/30=4 hours and 0 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 4 hour(s) i 0 minuts x 16 =64 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 4 hour(s) i 0 minuts x 2 =8 hour(s) i 0 minuts Total workload for the subject: 3 x 30=90 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 18 hour(s) i 0 minuts Workload structure: 64 hour(s) i 0 minuts (cources), 8 hour(s) i 0 minuts (preparation), 18 hour(s) i 0 minuts (additional work)
Student obligations
Consultations
Literature
Examination methods
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ANATOMY AND HISTOLOGY

Course:

ANATOMY AND HISTOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
10290	Obavezan	2	6	3+2+0

Programs	PHARMACY
Prerequisites	There is no requirement for applying.
Aims	Subject aims to familiarize students with the structure of a healthy human body. Other aim is to familiarize students with basic principles of organization of cells, tissues and histological structure of organs.
Learning outcomes	After completed one-semestral course and passing the Anatomy and Histology exam, the Pharmacy student should have the following learning outcomes: 1. Knows the human skeleton and movable joints, the function and innervation of the muscles. 2. Knows the segments of the peripheral and central nervous system, as well as their connections and role, and the function and the structure of the senses. 3. Knows the basics of the function, appearance and structure of the organs of the cardiovascular and respiratory tract. 4. Knows the basics of the function, appearance and the structure of the digestive and urogenital tract. 5. Uses the knowledge of the morphology and function of the organs and systems and applies it during the attending of professional exams. 6. Understands the connection between the structure, function and processes on the cellular, tissue and organ systems in the organism. 7. Explains the structure and the main processes of the prokaryotic and eukaryotic cell. 8. Recognizes and explains the histological structure of the tissues and organ systems of the human body.
Lecturer / Teaching assistant	Professor M. Radunović, MD, Professor A. Vuksanović Božarić, MD, Professor Lj.Vučković, MD, and assistants.
Methodology	Lectures, practical classes, term papers, colloquia, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	1.Anatomy – introduction. Osteologia – introduction. Bones of upper extremity. 2. Structure of cells, structure and function of cell organelles. Histological structure and classification of epithelial tissue.
I week exercises	1.Osteologia – introduction. Bones of upper extremity. 2. Structure of cells, structure and function of cell organelles. Histological structure and classification of epithelial tissue.
II week lectures	1. Bones of thorax and vertebral column. 2. Histological structure and classification of connective tissue.
II week exercises	1. Bones of thorax and vertebral column. 2. Histological structure and classification of connective tissue.
III week lectures	1. Bones of lower extremity. 2. Muscle tissue (smooth, skeletal and cardiac).
III week exercises	1. Bones of lower extremity. 2. Muscle tissue (smooth, skeletal and cardiac).
IV week lectures	1. Head bones. 2. Nerve tissue and histological structure of the nervous system organs (spinal cord, cerebellum, cerebrum).
IV week exercises	1. Head bones. 2. Nerve tissue and histological structure of the nervous system organs (spinal cord, cerebellum, cerebrum).
V week lectures	1. Arthrologia – introduction, description and types of joints. 2. Histological structure of organs of the immune system (thymus, tonsils, spleen and lymph node).
V week exercises	1. Arthrologia – introduction, description and types of joints. 2. Histological structure of organs of the immune system (thymus, tonsils, spleen and lymph node).
VI week lectures	1. Myologia – introduction. Muscles of extremities. 2. Histological structure of organs of the cardiovascular system ( arteries, veins, heart).
VI week exercises	1. Myologia – introduction. Muscles of extremities. 2. Histological structure of organs of the cardiovascular system ( arteries, veins, heart).
VII week lectures	1. Muscles of head, neck, thorax and abdomen. 2. Histological structure of organs of the endocrine system (thyroid, parathyroid, adrenal and pituitary gland).
VII week exercises	1. Muscles of head, neck, thorax and abdomen. 2. Histological structure of organs of the endocrine system (thyroid, parathyroid, adrenal and pituitary gland).
VIII week lectures	1. Neurologia – introduction. Nerves of extremities. Colloquium I 2. Histological structure of organs of the respiratory system (trachea, lungs).
VIII week exercises	1. Neurologia – introduction. Nerves of extremities. Colloquium I 2. Histological structure of organs of the respiratory system (trachea, lungs).
IX week lectures	1. Nerves of thorax and abdomen. Cranial nerves. 2. Histological structure of organs of the digestive tract (tongue, stomach, intestine).
IX week exercises	1. Nerves of thorax and abdomen. Cranial nerves. 2. Histological structure of organs of the digestive tract (tongue, stomach, intestine).
X week lectures	1. Spinal cord, brainstem, cerebellum. 2. Histological structure of organs of the digestive tract (salivary glands, liver, pancreas, gall blader).
X week exercises	1. Spinal cord, brainstem, cerebellum. 2. Histological structure of organs of the digestive tract (salivary glands, liver, pancreas, gall blader).
XI week lectures	1. Midbrain, forebrain. 2. Colloquium H
XI week exercises	1. Midbrain, forebrain. 2. Colloquium H
XII week lectures	1. Main pathways, eye and ear. 2. Histological structure of organs of the urinary system ( kidney, bladder and ureter).
XII week exercises	1. Main pathways, eye and ear. 2. Histological structure of organs of the urinary system ( kidney, bladder and ureter).
XIII week lectures	1. Cardiovascular and respiratory system. 2. Histological structure of organs of the male reproductive system (testis, seminal vesicles, vas deferens, prostate).
XIII week exercises	1. Cardiovascular and respiratory system. 2. Histological structure of organs of the male reproductive system (testis, seminal vesicles, vas deferens, prostate).
XIV week lectures	1. Digestive system. 2. Histological structure of organs of the female reproductive system (uterus, fallopian tube, ovary).
XIV week exercises	1. Digestive system. 2. Histological structure of organs of the female reproductive system (uterus, fallopian tube, ovary).
XV week lectures	1. Urogenital system. Colloquium II 2. Histological structure of senses (cornea, retina, cochlear canal, skin).
XV week exercises	1. Urogenital system. Colloquium II 2. Histological structure of senses (cornea, retina, cochlear canal, skin).

Student workload	Weekly: 6 credits x 40/30 = 8 hours Structure: 3 hours of lectures (2 hours of Anatomy and 1 hour of Histology); 2 hours of practical classes (1 hour of Anatomy and 1 hour of HIstology); 3 hours of independent work; During the semester: Classes and final exam: 16 hours x 8 = 128 hours; Necessary preparations before the beginning of semester (administration, enrollment, certification...) 8 hours x 2 = 16 hours Overall workload: 6 x 30 = 180 hours Supplementary work from 36 hours Structure of workload: 128 hours + 16 hours + 36 hours = 180 hours
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 3 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	It is compulsory to the students theoretical and practical teaching.
Consultations	Consultations once a week for two academic hours for all teachers and staff.
Literature	Čukuranović R, Pavlović S, Stefanović N, Antić S, Vasović Lj, Arsić S. Anatomija čoveka za studente strukovnih studija. Niš: Autorsko izdanje; 2008. Avramović V, Rančić G, Nikolić I. Histologija autorizovana skripta i praktikum za studente farmacije i strukovnih studija. Niš: Autorsko izdanje; 2011. Saraga Babić M, Puljak L, Mardešić S, Kostić S, Sapunar D. Embriologija i histologija. Sveučilište u Splitu: Split; 2014.
Examination methods	The presence on lectures and practical classes: 10 points (6 points – Anatomy and 4 points – Histology) Anatomy - Colloquium I – Locomotory system – 5 to 12 points; Colloquium II – Nervous system – 5 to 12 points; Histology – Colloquium 5-12 points; Histology – term paper - 2 to 4 points; Final exam: 50 points (Anatomy - Organs and senses - 30 points; Histology – 20 points); Formation of mark: presence + CI + C II + CH + term paper H + final exam; A passing grade is obtained if a minimum of 50 points is collected;
Special remarks	No.
Comment	Consultations and term papers will be held according to an agreement with students. Exercises follow the schedule of lectures in Anatomy and Histology.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ANALYTICAL CHEMISTRY I

Course:

ANALYTICAL CHEMISTRY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5095	Obavezan	2	7	3++4

Programs	PHARMACY
Prerequisites
Aims	Getting of basic knowledge in qualitative analysis with the aim of training students to solve analytical problems: getting of knowledge about heterogeneous equilibria; sample preparation and identification of ions using selected reagents; identification of unknown substances; separation and identification of ions by chromatographic and extraction techniques
Learning outcomes	1. Apply acquired knowledge about heterogeneous systems and assess the conditions of deposition and dissolution; 2. Assess and apply the appropriate sample preparation procedure; 3. Based on the acquired knowledge, he knows the identification of ions in the analysis of substances; 4. Apply separation techniques in the separation, purification and concentration of analytes.
Lecturer / Teaching assistant	Associate professor Vesna Vukašinović-Pešić; Associate Snežana Vukanović, PhD
Methodology	Lectures, laboratory exercises, Control tests. Colloquiums. Consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Getting to know the subject and sharing information about the subject. Introduction. Definition and division of analytical chemistry according to techniques and methods. Practical basics of qualitative chemical analysis. Classification of cations. I group of cations
I week exercises	Introduction. Familiarizing the students with the laboratory settings. Literature
II week lectures	Chemical regularities in methods of identification and separation of analytes. II and III group of cations
II week exercises	Semimicro analysis of I group of cations
III week lectures	IV and V group of cations. Solutions and their properties.
III week exercises	Semimicro analysis of II group of cations
IV week lectures	Chemical equilibrium. Equilibrium constants.
IV week exercises	Semimicro analysis of III group of cations
V week lectures	Acid-base reactions. Acids and bases. Acid base constants.
V week exercises	Semimicro analysis of IV and V groups of cations
VI week lectures	Equilibria in polyprotic systems. Graphic presentation of acid-base balances.
VI week exercises	Analysis of the cation mixture.
VII week lectures	Hydrolysis of salt. Calculation tasks.
VII week exercises	I colloquium
VIII week lectures	Complexes and their role in Analytical Chemistry. Complex ion equilibria. Test I
VIII week exercises	Semimicro analysis of I group of anions. I colloquium (additional offering)
IX week lectures	Precipitation reactions. Solubility product.
IX week exercises	Semimicro analysis of II group of anions.
X week lectures	Precipitation and separation of ions by controlling the concentration of the precipitating reagent.
X week exercises	Semimicro analysis of III and IV groups of anions.
XI week lectures	Redox reactions and their role in analytical chemistry.
XI week exercises	analysis of solid salt
XII week lectures	Analysis of a real sample. Test II
XII week exercises	II colloquium
XIII week lectures	The theory of extraction
XIII week exercises	extraction
XIV week lectures	Chromatographic separations of cations
XIV week exercises	Chromatographic
XV week lectures	Preparations for the exam
XV week exercises	I colloquium (additional offering)

Student workload
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 4 sat(a) practical classes 0 excercises 2 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend classes, take control tests, complete all laboratory exercises and both colloquiums. Before the exercises, knowledge is checked (entrance colloquium, and after the exercise, the student submits the exercise with the results for signature to the assistant).
Consultations
Literature	1.Vera Kapetanović,Milena Jelikić- Stankov,Analitička hemija i uvod u semimikrokvalitativnu hemijsku analizu,Univerzitet u Beogradu(1998). 2.Milena Jelikić-Stankov,Vera Kapetanović i dr. Semimikro kvalitativna hemijska,praktikum za studente farmacije,TMF Univerziteta u Beogradu(2004). 3. Jelena Savić i Momir Savić, Osnovi Analitičke hemije, klasične metode, Sarajevo:Svjetlost, 1989.
Examination methods	Tests (5+5 poens), Laboratory exercises (10 poens), Colloquiums (15+15 poens), Final exam (50 poens)
Special remarks	In order for the student to take the exam, he must have completed and certified all laboratory exercises.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BOTANICS

Course:

BOTANICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5096	Obavezan	2	7	3++3

Programs	PHARMACY
Prerequisites	None.
Aims	Acquiring knowledge about the basics of morphology, anatomy, physiology and ecology of pharmaceutically important plants. Localization of primary and secondary metabolites and their biological roles. Introduction to the classification systems as information systems. Identification of selected groups of medicinal plants.
Learning outcomes	Capacitating students to: explain the morphological and anatomical characteristics of plant organs important for pharmacy; describe and explain the basic physiological processes of plants; correctly name and classify selected taxa; predict the properties of taxa based on their systematic affiliation; access the requested information about the plants of interest to pharmacy; recognize groups of medicinal plants.
Lecturer / Teaching assistant	Mijat Božović, Danka Caković
Methodology	Theoretical and practical classes, field work, consultation.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction; Plant cell; Organization of plant body.
I week exercises	Plant cell and starch granules.
II week lectures	Plant tissues: meristem and permanent.
II week exercises	Meristem tissue.
III week lectures	Plan organs: seedling, root, shoot.
III week exercises	Vascular tissues.
IV week lectures	Flower and plant reproduction.
IV week exercises	Stem and root cross sections.
V week lectures	Plant physiology.
V week exercises	Secondary growth; Leaf anatomy.
VI week lectures	COLLOQUIUM I
VI week exercises	Stamen and ovary cross sections.
VII week lectures	Plant taxonomy and nomenclature; Algae, fungi and lichens.
VII week exercises	TEST
VIII week lectures	Mosses, horsetails, ferns, gymnosperms.
VIII week exercises	Algae, fungi and lichens.
IX week lectures	Flowering plants: Magnoliopsida class (Magnoliaceae-Primulaceae).
IX week exercises	Mosses, horsetails, ferns, gymnosperms.
X week lectures	Flowering plants: Magnoliopsida class (Rosaceae-Scrophulariaceae).
X week exercises	Floral formula; Dicotyledon representatives.
XI week lectures	Flowering plants: Magnoliopsida class (Rubiaceae-Asteraceae).
XI week exercises	Monocotyledon representatives.
XII week lectures	Flowering plants: Liliopsida class.
XII week exercises	Plant identification (Magnoliopsida).
XIII week lectures	Field work: plant representatives of the (sub)mediterranean part of Montenegro.
XIII week exercises	Plant identification (Liliopsida).
XIV week lectures	Field work: plant representatives of the continental part of Montenegro.
XIV week exercises	Plant identification; Herbarium preparing.
XV week lectures	COLLOQUIUM II
XV week exercises	Plant identification; Herbarium preparing.

Student workload
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Attending theoretical, practical and field classes.
Consultations	2 hours by week.
Literature	1) Jančić: Botanika farmaceutika, Službeni glasnik Beograd, 2012. 2) Domac: Flora Hrvatske, Školska knjiga Zagreb, 2002. 3) Petković, Merkulov, Duletić-Laušević: Anatomija i morfologija biljaka sa praktikumom, Biološki fakultet Beograd, 2014. 4) Tatić, Blečić: Sistematika i filogenija viših biljaka, Zavod za udžbenike i nastavna sredstva Beograd, 1984; 5) Nešković, Konjević, Ćulafić: Fiziologija biljaka, NNK Internacional Beograd, 2003; 6) Stevanović, Janković: Ekologija biljaka sa osnovama fiziološke ekologije biljaka, NNK Internacional Beograd, 2001.
Examination methods	Colloquium 2x15 points; Test 10 points. Final exam (herbarium 20 points + final colloquium 40 points).
Special remarks	Herbarium preparation and a minimum of 10 points are required prior to final colloquium.
Comment	Students themselves bear the costs of field work.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ORGANIC CHEMISTRY II

Course:

ORGANIC CHEMISTRY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5094	Obavezan	2	8	3++4

Programs	PHARMACY
Prerequisites	-
Aims	Acquiring knowledge of the stereochemical properties of organic molecules and stereochemical approach to organic reactions. Study of the properties of heterocyclic compounds and natural biomolecules. Knowing the basic laboratory techniques and their application to the synthesis and purification of organic compounds. Detection and the mutual functional group transformation.
Learning outcomes	1. Recognizes the stereoisomers and denotes the corresponding configuration isomers with stereochemical markings and shows the configuration of the molecules based on the labels; 2. Recognizes the stereochemical properties of the molecule and analyzes the effect of sterohemistry on reactivity; 3. Recognizes and designates basic heterocyclic compounds and defines the ways of their synthesis and characteristic reactions; 4. Use the acquired knowledge to recognize the structural characteristics, reactivity and properties of biomolecules (carbohydrates, proteins, lipids and nucleic acids); 5. Use the acquired knowledge to independently perform synthesis, purification and demonstration of simpler organic compounds.
Lecturer / Teaching assistant	assistant professor Vlatko Kastratović PhD Msc Marija Kaluđerović
Methodology	Lectures. Consultations. Laboratory exercises. Control test. Coloquium

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction. Stereochemistry. Enantiomer. Graphic representation of molecules. Configuration.
I week exercises	Basic supplies and operations in chemical laboratories. The basic physical properties of organic compounds
II week lectures	Racemic modifications. Conformations of acyclic compounds.
II week exercises	Methods of purification of organic compounds. Recrystallization. Purification of organic substances by extraction. Extraction by Soxlet.
III week lectures	Stereochemistry of cyclic compounds.
III week exercises	Production and purification of organic substances by distillation.
IV week lectures	Structure and chirality of allen, spiran and biphenyl. Stereoselective and stereospecific reactions. Asymmetric syntheses.
IV week exercises	Reactions biologically important functional groups.
V week lectures	Heterocyclic compounds, naming, non-aromatic heterocyclic compounds.
V week exercises	Test. Making of organic preparation: acetylsalicylic acid
VI week lectures	Structure, properties and reactions of aromatic heterocyclopentadiene. Chemistry of pyridine, quinoline, isoquinoline.
VI week exercises	Making of organic preparation: Benzyl alcohol and benzoic acid from benzaldehyde.
VII week lectures	Carbohydrates. Appointment, conformation and cyclical forms. Polyfunctional sugar chemistry.
VII week exercises	Carbohydrates. Monosaccharides. Reduction reactions. Color reaction. Building ozazona.
VIII week lectures	Carbohydrates-Continuation. Oxidation, reduction, extension, and shortening of the series. Construction of glycosides. Determining the structure.
VIII week exercises	Disaccharides. The hydrolysis of the polysaccharides.
IX week lectures	Disaccharides. Polysaccharides.
IX week exercises	Proteins. Solubility and precipitation of the protein. Probatives of the reaction of the protein.
X week lectures	Colloquium. Synthesis of amino acids. Physical and chemical properties of amino acids. Peptide bond.
X week exercises	Making of organic preparation: 2-chloro-2-methyl-propane
XI week lectures	Correctional Colloquium. Peptides. Synthesis of polypeptides in solution and solid phase.
XI week exercises	Making of organic preparation: α-D-Penta-acetyl-glucose; β -D-Penta-acetyl-glucose;
XII week lectures	Primary and secondary structure of polypeptides. Determination of the primary structure. Biological important polypeptides.
XII week exercises	Lipids. Basic hydrolysis of lipids. Soaps.
XIII week lectures	Lipids. Division and composition. Compatible lipids: free and complex lipids
XIII week exercises	Making of organic preparation: Ethyl acetate
XIV week lectures	Unsaponifiable lipids, steroids, terpenes and vitamins soluble in lipids, prostaglandins.
XIV week exercises	Making of organic preparation: Ethyl bromide
XV week lectures	Nucleosides. Nucleotides. Nucleic acid. Structure, properties, synthesis.
XV week exercises	Compensation exercise.

Student workload	A week: 10 x 40/30 = 13 hours i 20 min. Structure: 3 hours of lectures 4 hours exercise 6 hours min. of student work, including consultations. During the semester: Teaching and the final exam: (13 hours and 20 min) x 16 = 213 hours and 20 min. Necessary preparation (before semester administration, enrollment and verification): (13 hours and 20 min) x 2 = 26 hours and 40 min Total hours for the course: 10 x 30 = 300 hours Aadditional work to prepare the corrective final exam, including the exam taking 0 do 60 sati (the remaining time of the first two items to the total work hours for the subject of 300 hours) Structure: 213 hours and 20 min (lecture) + 26 sati i 40 minuta (preparation) + 60 hours (additional work).i 20
Per week	Per semester
8 credits x 40/30=10 hours and 40 minuts 3 sat(a) theoretical classes 4 sat(a) practical classes 0 excercises 3 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 10 hour(s) i 40 minuts x 16 =170 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 10 hour(s) i 40 minuts x 2 =21 hour(s) i 20 minuts Total workload for the subject: 8 x 30=240 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 48 hour(s) i 0 minuts Workload structure: 170 hour(s) i 40 minuts (cources), 21 hour(s) i 20 minuts (preparation), 48 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend classes, do all the laboratory exercises planned curriculum, resolve and home exercises, work control test and coloquium.
Consultations	Consultations: Monday: 9-11am, Thursday: 9-11am.
Literature	1. Vollhardt K.P.C., Schore N.E. 2004. Organic chemistry: structure and function, (editor: Bogdan Šolaja), IV edition, Data status: Nauka, Belgrade 2. Mihailović M. Lj. 1990. Fundamentals of Theoretical Organic Chemistry and Stereochemistry, 4th ed. Construction book, Belgrade 3. Pavlov S. 2001. Introduction to the chemistry of heterocyclic compounds. Grafopan, Belgrade 4. Čeković Z. 1995. Experimental organic chemistry. Faculty of Chemistry, Belgrade 5. Savić V., Tokić Z., Simić M., Tasić G., Dilber S. 2006. Practical course in organic chemistry for students of the Faculty of Pharmacy, Faculty of Pharmacy, Belgrade
Examination methods	The presence of the lectures and exercises: 0 - 10 pts; Tests: 0 - 10 pts. Colloquium: 0 - 30 pts.; Final exam : 0 - 50 pts.
Special remarks	Teaching (P + V) is performed in the form of lectures and exercises for up to 10 students in the group.
Comment	-

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE I

Course:

ENGLISH LANGUAGE I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
2093	Obavezan	3	2	2+1+0

Programs	PHARMACY
Prerequisites	None.
Aims	Acquiring the skills of understanding the spoken and written English dealing with medicine and pharmacy. Upgrading language skills.
Learning outcomes	At the end of this course student will be able to: - enhance his or her ability to use effective communication strategies to repair or avoid possible breakdown in communication with patients - develop the awareness of body language in order to be able to better read and interpret the patient’s physical and emotional signs - demonstrate that he or she is really listening to the patient and assimilate the information given, as well as its relevance to an eventual diagnosis - improve use of intonation and word stress in order to build rapport with the patient, give encouragement and show sensitivity - acquire skills of communicating in pharmaceutical industry - develop linguistic skills and specialist vocabulary in the area of drug production and quality control - widen the understanding of cultural issues and the impact of his or her own cultural background on both the patient and the interview itself.
Lecturer / Teaching assistant	Prof. dr Nataša Kostić, dr Dragana Čarapić
Methodology	Lectures and discussions.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to the course
I week exercises	Job profiles, professions and departments
II week lectures	Receiving the patient
II week exercises	Clinical research assistant
III week lectures	Asking the opening question and setting the agenda for the interview
III week exercises	Job title: Chemist
IV week lectures	The presenting complaint
IV week exercises	Cultural differences in marketing drugs and medicine
V week lectures	Patient-centered approach to history taking
V week exercises	New drug development and launches
VI week lectures	Taking history of the presenting complaint (group I)
VI week exercises	Substance discovery and drug development
VII week lectures	Taking history of the presenting complaint (group II)
VII week exercises	Mid-term test
VIII week lectures	Past medical and family history
VIII week exercises	Drug dosage forms
IX week lectures	Writing an effective patient note, summarising and structuring the interview
IX week exercises	Vježbe: Categories of drugs
X week lectures	Role play: taking a focused PMH (group I)
X week exercises	Remedial mid-term test
XI week lectures	Role play: taking a focused PMH (group II)
XI week exercises	Hospital in-patient dosage form survey results
XII week lectures	The social history
XII week exercises	How many drug categories do we need?
XIII week lectures	Ensuring an effective telephone consultation, summarizing and checking information
XIII week exercises	Quality assurance and auditing
XIV week lectures	Examining a patient
XIV week exercises	Pharmaceutical internal audit report
XV week lectures	Explaining examination procedures and giving effective instructions in a patient-friendly manner
XV week exercises	Final exam – mock test

Student workload
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises -1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Students are obliged to attend the classes, participate in discussions, do tasks and take tests.
Consultations	kostic@ucg.ac.me
Literature	1. McCullagh M, Wright R. Good Practice: Communication Skills in English for the Medical Practitioner. Cambridge: Cambridge University Press; 2008. 2. Buchler M, Jaehnig K, Matzig G, Weindler T. English for the Pharmaceutical Industry. Oxford: Oxford University Press; 2010. 3. Oxford Concise Medical Dictionary. Oxford: Oxford University Press; 2003. 4. Mićić S. Medicinski rečnik. Beograd: Zavod za udžbenike; 2007.
Examination methods	Mid-term exam: 40 points, Presentation: 10 points, Final exam: 50 points
Special remarks	-
Comment	The lectures are taught in English and Montenegrin.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE I

Course:

ENGLISH LANGUAGE I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
2093	Obavezan	3	2	2+1+0

Programs	PHARMACY
Prerequisites	None.
Aims	Acquiring the skills of understanding the spoken and written English dealing with medicine and pharmacy. Upgrading language skills.
Learning outcomes	At the end of this course student will be able to: - enhance his or her ability to use effective communication strategies to repair or avoid possible breakdown in communication with patients - develop the awareness of body language in order to be able to better read and interpret the patient’s physical and emotional signs - demonstrate that he or she is really listening to the patient and assimilate the information given, as well as its relevance to an eventual diagnosis - improve use of intonation and word stress in order to build rapport with the patient, give encouragement and show sensitivity - acquire skills of communicating in pharmaceutical industry - develop linguistic skills and specialist vocabulary in the area of drug production and quality control - widen the understanding of cultural issues and the impact of his or her own cultural background on both the patient and the interview itself.
Lecturer / Teaching assistant	Prof. dr Nataša Kostić, dr Dragana Čarapić
Methodology	Lectures and discussions.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to the course
I week exercises	Job profiles, professions and departments
II week lectures	Receiving the patient
II week exercises	Clinical research assistant
III week lectures	Asking the opening question and setting the agenda for the interview
III week exercises	Job title: Chemist
IV week lectures	The presenting complaint
IV week exercises	Cultural differences in marketing drugs and medicine
V week lectures	Patient-centered approach to history taking
V week exercises	New drug development and launches
VI week lectures	Taking history of the presenting complaint (group I)
VI week exercises	Substance discovery and drug development
VII week lectures	Taking history of the presenting complaint (group II)
VII week exercises	Mid-term test
VIII week lectures	Past medical and family history
VIII week exercises	Drug dosage forms
IX week lectures	Writing an effective patient note, summarising and structuring the interview
IX week exercises	Vježbe: Categories of drugs
X week lectures	Role play: taking a focused PMH (group I)
X week exercises	Remedial mid-term test
XI week lectures	Role play: taking a focused PMH (group II)
XI week exercises	Hospital in-patient dosage form survey results
XII week lectures	The social history
XII week exercises	How many drug categories do we need?
XIII week lectures	Ensuring an effective telephone consultation, summarizing and checking information
XIII week exercises	Quality assurance and auditing
XIV week lectures	Examining a patient
XIV week exercises	Pharmaceutical internal audit report
XV week lectures	Explaining examination procedures and giving effective instructions in a patient-friendly manner
XV week exercises	Final exam – mock test

Student workload
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises -1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Students are obliged to attend the classes, participate in discussions, do tasks and take tests.
Consultations	kostic@ucg.ac.me
Literature	1. McCullagh M, Wright R. Good Practice: Communication Skills in English for the Medical Practitioner. Cambridge: Cambridge University Press; 2008. 2. Buchler M, Jaehnig K, Matzig G, Weindler T. English for the Pharmaceutical Industry. Oxford: Oxford University Press; 2010. 3. Oxford Concise Medical Dictionary. Oxford: Oxford University Press; 2003. 4. Mićić S. Medicinski rečnik. Beograd: Zavod za udžbenike; 2007.
Examination methods	Mid-term exam: 40 points, Presentation: 10 points, Final exam: 50 points
Special remarks	-
Comment	The lectures are taught in English and Montenegrin.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / COLOIDAL AND SURFACE CHEMISTRY

Course:

COLOIDAL AND SURFACE CHEMISTRY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7613	Obavezan	3	3	2+1+0

Programs	PHARMACY
Prerequisites	-
Aims	Acquiring theoretical and practical knowledge about the characteristics and behavior of colloidal system, the characteristics of natural and synthetic macromolecules and supramolecular structures, surface active agents and disperse systems in order to better understand the technology of making medical preparations. Also, the goal is introducing students to modern scientific achievements in the field of application of colloids in pharmacy.
Learning outcomes	After completing the course, the student will be able to: -define dispersible, macromolecular and micellar colloids -describe the ways of obtaining and purification of colloids - clarify and explain the optical, kinetic and electrical properties of colloidal systems -define the stability of colloid systems and coagulation processes -differ techniques of determining the rheological properties of colloids - use acquired knowledge of colloidal systems in the manufacture of drugs and pharmaceutical preparations.
Lecturer / Teaching assistant	Full professor Ivana Bošković; PhD Jana Mišurović
Methodology	Lectures, exercises, seminar paper and test. Consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to the colloidal chemistry. Structure of the colloidal particle.
I week exercises	Presentation of the structure of the colloidal particle.
II week lectures	The classification of colloidal systems.
II week exercises	Obtaining a positive colloid system.
III week lectures	The formation of colloid systems.
III week exercises	Obtaining a negative colloid system.
IV week lectures	Colloidal surfactants, their structure and their practical significance.
IV week exercises	Preparation of colloidal AgCl.
V week lectures	Purification and separation of colloids.
V week exercises	Topics for the seminar paper.
VI week lectures	The size and the shape of colloidal particles.
VI week exercises	Seminar paper.
VII week lectures	The optical properties of colloidal systems.
VII week exercises	Seminar paper.
VIII week lectures	Kinetic properties of colloidal systems.
VIII week exercises	Seminar paper.
IX week lectures	The surface phenomena in colloid chemistry (surface tension, adsorption).
IX week exercises	Seminar paper.
X week lectures	Viscosity and rheological properties of colloidal systems.
X week exercises	Seminar paper.
XI week lectures	Electrical properties of colloids.
XI week exercises	Determination of the rate of colloidal particles in the electrical field.
XII week lectures	Stability of colloidal systems and colloid coagulation.
XII week exercises	Determination of coagulation threshold and electrolyte coagulant power.
XIII week lectures	Specific colloid systems. The emulsions.
XIII week exercises	The examples of kinetics of fast coagulation of liofobic colloids by electrolytes.
XIV week lectures	Dispersions with gas phase. Aerosols and foams.
XIV week exercises	Seminar paper.
XV week lectures	The natural and synthetic macromolecules.
XV week exercises	Test.

Student workload	Weekly: 3 ECTS x 40/30= 4 h; In semester: 4 x 16= 64h
Per week	Per semester
3 credits x 40/30=4 hours and 0 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 1 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 4 hour(s) i 0 minuts x 16 =64 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 4 hour(s) i 0 minuts x 2 =8 hour(s) i 0 minuts Total workload for the subject: 3 x 30=90 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 18 hour(s) i 0 minuts Workload structure: 64 hour(s) i 0 minuts (cources), 8 hour(s) i 0 minuts (preparation), 18 hour(s) i 0 minuts (additional work)
Student obligations	The students are required to attend classes, to do exercises, defense seminar, take the test and the final exam.
Consultations	The term for consultations will be specified in agreement with the students,.
Literature	1. Tharwat F. Tadros: Colloid stability and application in pharmacy, Wiley-VCH Verlag, Berlin, 2007. 2. Monzer Fanun: Colloids in drug delivery, CRC Press/
Examination methods	Activity during the lectures: 5 points Exercises Activity: 5 points Seminar paper: 20 points Test: 20 points Final exam: 50 points
Special remarks	-
Comment	-

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / IMMUNOLOGY

Course:

IMMUNOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5955	Obavezan	3	4	2++2

Programs	PHARMACY
Prerequisites	NO
Aims	Learning about the characteristics of innate and adaptive immunity in the defense against infectious microorganisms, the study of pathogenetic mechanisms of diseases caused by dysfunction of the immune system and the immune response to tumor antigens and transplants
Learning outcomes	1. Understand the meaning of immunity and the immune system; 2. Reproduce the basic assumptions about the functioning of the human immune system; 3. Explain the role of the individual components of the immune system; 4. Define the functional division of innate and acquired immunity; 5. Recognise the reactions of the individual functional units of the immune system and their connections; 6. Compare the manners in which the immune system responds to what is its own and what is foreign, and understand the consequences which these reactions may have on the body; 7. Identify the disorders in the functioning of the immune system; 8. Independently select the basic diagnostic tests for immunology testing.
Lecturer / Teaching assistant	Dr sci med Vjeroslava Slavić Dr Tamara Jovićević
Methodology	Lectures, Laboratory exercises, The Colloquium (Control tests), Consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Immunology - What is This?
I week exercises
II week lectures	Introduction to the Immune System: The Nomenclature, General Properties
II week exercises
III week lectures	Innate Immunity: Cell Components, Complement System, Cytokines
III week exercises	The antigen-antibody (Ag-Ab) reaction; basic characteristics and practical application
IV week lectures	Antigen Capture and Presentation to Lymphocytes
IV week exercises	Agglutination and its practical application. Reactions of direct and indirect agglutination test for the final identification of the corresponding antigen or specific antibody.
V week lectures	Antigen Recognition in the Adaptive Immune System
V week exercises	Immunoprecipitation and its practical application. Immunoprecipitation techniques in the liquid and semi-solid medium.
VI week lectures	Cell-Mediated Immune Response
VI week exercises	The antigen-antibody reaction dependent on the complement and their practical application (titration of complement, complement fixation, lymphocytotoxic test)
VII week lectures	Effector Mechanisms of Cell-Mediated Immunity
VII week exercises	The antigen-antibody reaction with labeled antigens or antibodies (ELISA, direct and indirect immunofluorescence - DIF and IIF, Radioimmunoassay -RIA, Immunoblot Assay)
VIII week lectures	Humoral Immune Response
VIII week exercises	Laboratory test methods of adaptive immune cells (isolation of peripheral blood mononuclear cells, phenotyping and counting of leukocytes by flow cytometry, in vivo and in vitro assays of function of T and B lymphocytes)
IX week lectures	Effector Mechanisms of Humoral Immunity
IX week exercises	Laboratory test method, cells of innate immunity (function tests phagocytes and NK cells)
X week lectures	Colloquium (test exam I)
X week exercises
XI week lectures	Immunologic Tolerance and Autoimmunity
XI week exercises	The use of molecular biology techniques in medical diagnostics (Hybridization reactions, Western blotting, Southern blotting, Northern blotting, polymerase chain reaction - PCR, RT-PCR)
XII week lectures	Immune Responses Against Tumors and Transplants
XII week exercises
XIII week lectures	Hypersensitivity Diseases: Disorders Caused by Immune Responses
XIII week exercises
XIV week lectures	Congenital and Acquired Immunodeficiencies
XIV week exercises
XV week lectures	Colloquium (test exam II)
XV week exercises

Student workload	4 ECTS credits x 40/30=5h i 20 min 2 h lectures 1 h laboratory exercises 2 h i 20 min. student personal work including consultation
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Attending lectures and laboratory exercises, making seminar works
Consultations	Consultations with relevant teacher and collaborator during the semester, in relation to lectures, making seminar works and preparation of exercises.
Literature	1. Abul K. Abbas, Andrew H. Lichtman. Osnovna imunologija: funkcionisanje i poremećaji imunskog sistema. Treće izdanje, 2009. Redaktor izdanja na srpskom jeziku Zorica Ramić. Izdavač: Data status, Beograd; Print: SP Print, Novi Sad 2. Valentina Arsić i
Examination methods	The presence to lectures and exercises: up to 15 points (1 point per week + bonus), Practical Exam (mandatory) 0-10 points, Seminar Work (mandatory) 0-5 points, The Colloquium 2x0-10 points; Final Exam (oral): It is used for forming the final grade. The
Special remarks
Comment	Additional information can be obtained from the subject teacher, head of the study program with Dean for Academic Affairs.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHYSICAL CHEMISTRY

Course:

PHYSICAL CHEMISTRY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5953	Obavezan	3	5	3++2

Programs	PHARMACY
Prerequisites	There is no conditionality.
Aims	Acquiring knowledge in the field of physical chemistry which are essential to understanding the significance processes for preparation, stability and mechanisms of pharmaceutical product effect on organism.
Learning outcomes	1. Understand the meaning of a physical-chemical processes so as to be able to apply them in the pharmaceutical industry; 2. Reproduce the basic theoretical concepts and models of physical-chemical properties of matter in all states of aggregation; 3. Explain the physical and chemical properties of colloidal systems and processes at the surface phase interface; 4. Define the basic laws of chemical thermodynamics; 5. Identify the methods and techniques applied in the study of kinetics and the mechanisms of chemical reactions; 6. Recognise the role of catalytic processes in the mechanism of action of pharmaceutical products; 7. Compare the types of radioactivity, their characteristics and effects of action on the living organism; 8. Independently select the physicochemical methods in preparing certain pharmaceutical product.
Lecturer / Teaching assistant	Full Professor Ivana Bošković; PhD Jana Mišurović
Methodology	Lectures, exercises, homework, consultation, test, exam.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction. Gas aggregate state. Gas laws.
I week exercises	Calculation exercises: gas laws.
II week lectures	The basic equation of the kinetic theory of gases and its application. Real gases.
II week exercises	Calculation exercises: application the basic equation of kinetic theory of gases.
III week lectures	Solid aggregate state. Crystalline and amorphous state of matter.
III week exercises	Calculation exercises: real gases and specific molar heats of gas.
IV week lectures	Liquid aggregate state.
IV week exercises	Calculation exercises: dependence of vapor pressure on temperature; viscosity of gas and liquid.
V week lectures	Phenomena at the boundary surface of phases. Surface tension of liquid. Adsorption. Sorption isotherms.
V week exercises	Calculation exercises: liquid surface tension and determination of characteristic parameters in sorption isotherms.
VI week lectures	Dispersion systems. Colloid solutions.
VI week exercises	Calculation exercises: determining the charge of a colloidal particle, ceta potential.
VII week lectures	Emulsions. Gels. Aerosols.
VII week exercises	Experimental exercise: Verification of Gay-Luccass law. First test.
VIII week lectures	Solutions. Classification and characteristics. Solubility. Colligative properties of the solutions.
VIII week exercises	Determining the viscosity coefficient of liquids using the Ostwalds method. Calculation exercises: colligative properties of solutions. Correctional first test.
IX week lectures	Chemical thermodynamics. Thermochemistry. The first law of thermodynamics.
IX week exercises	Experimental exercise: Determining the surface tension of a liquid. Calculation exercises: thermochemical laws and enthalpy of a chemical reaction.
X week lectures	The second law of thermodynamics. Entropy.
X week exercises	Experimental exercise: Determination of the Freundlichs adsorption isotherm for acetic acid sorption process on activated carbon.
XI week lectures	Gibbs and Helmholtz energy. Third law of thermodynamics.
XI week exercises	Experimental exercise: Preparation of colloidal systems.
XII week lectures	Chemical kinetics. Reactions of the first, second and third order. Complex reactions.
XII week exercises	Experimental exercise: Determination of the integral enthalpy of dissolution. Calculation exercises: determination of the rate constant of a chemical reaction and the half-time of the reaction.
XIII week lectures	Catalysts. Homogeneous and heterogeneous catalysis.
XIII week exercises	Experimental exercise: Determination of the dependence of water vapor pressure on temperature using the dynamic method. The second test.
XIV week lectures	Radioactivity. Natural and the artificial radioactivity.
XIV week exercises	Experimental exercise: Determination of the rate of iodide ions oxidation by persulfate ions.
XV week lectures	Correctional second test.
XV week exercises	Experimental exercise: Determination of the rate constant of the sucrose inversion reaction.

Student workload	Weekly : 6 ECTS x 40/30 = 8h. During semester = 6 x 30 = 180 h.
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 3 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend classes, as well as doing home exercises, completed all laboratory exercises and both tests. If students take the correctional test (exam), only points from correctional test (exam) will be recognized.
Consultations	Tuesday: 9-11 h; Friday 9-11 h
Literature	1. D. Malešev,Odabrana poglavlja fizičke hemije,Beograd 2003. 2. M.Medenica, D.Malešev,Eksperimentalna fizička hemija,Beograd 2002. 3. V.Kuntić, M.Aleksić, L.Pavin,N.Pejić, Zbirka zadataka iz fizičke hemije,Beograd 2003. 4. Atkins P.W., Physical Chemistry,
Examination methods	- Activities during exercise: (0 - 4 pts), - Homeworks : ( 0 - 3 pts), - I test : ( 0 - 20 pts), - II test: ( 0 - 20 pts), - Final exam : ( 0 - 50 pts), Students pass the exam if the combined total score is at least 50 points.
Special remarks	-
Comment	-

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL MICROBIOLOGY

Course:

PHARMACEUTICAL MICROBIOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5954	Obavezan	3	5	2++2

Programs	PHARMACY
Prerequisites	No preconditions.
Aims	Introduction to the basic principles of work in microbiological laboratory and etiological agents of infectious diseases, their identification and importance; The effect of antimicrobials agents, acquisition of resistance and the importance of rational use of antimicrobial medicaments; Epidemiology and prevention of infectious diseases; Sterilization and disinfection; Application of microorganisms in the pharmacy.
Learning outcomes	1. Recognise the importance of the normal microflora of the human body, as well as their mutual relationship; 2. Recognise significant etiological microorganisms within certain infections; 3. Use the acquired knowledge about the application of antimicrobial therapy and the possible negative consequences of its application; 4. Analyse the connection between microorganisms from the external environment and the normal human flora, and the contamination of pharmaceutical products, as well as be aware of the importance of the principles of good manufacturing practice; 5. Use the acquired knowledge to contribute to preventing the development of resistant microorganisms and to preserving health in the community.
Lecturer / Teaching assistant	Prof. dr Vineta Vuksanović – Chief of the Subject, Prof. dr Gordana Mijović, Dr Milena Lopičić, Dr Marijana Mimović, Dipl.bioteh. Vaid Frljučkić.
Methodology	Lectures and exercises, seminars, control tests, regular consultations, preparation for the final exam.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction in microbiology and classification of the microorganism. Structure, function and bacterial physiology.
I week exercises	Rules of conduct in the microbiological laboratory. Staining and visualization of bacterial structure by microscopy.
II week lectures	The genome of the bacteria. Pathogenicity, virulence factors and virulence of bacteria
II week exercises	Sampling and transport of material for bacteriological analysis. Cultivation and identification of bacteria.
III week lectures	Antibiotics and chemotherapeutics. Mechanisms of bacterial resistance.
III week exercises	Susceptibility testing of bacteria in vitro (antibiogram) and the destruction of bacteria (sterilization and disinfection).
IV week lectures	Staphylococcus aureus and Streptococcus pyogenes.
IV week exercises	Diagnostics of: Staphylococcus aureus, Streptococcus pyogenes.
V week lectures	Pathogens of the Neisseria genus and Haemofilus influenza. The etiological agents of tuberculosis.
V week exercises	Diagnostics of pathogenic Neisseria, Haemofilus influenzae and Mycobacterium tuberculosis.
VI week lectures	The primary pathogenic intestinal bacteria. The anaerobic and non-fermentative bacteria.
VI week exercises	Diagnostics of family Enterobacteriaceae. Diagnostics of genus Clostridium, other anaerobic bacteria and non-fermentative bacteria.
VII week lectures	STD and bacteria: Treponema pallidum, Chlamydia trachomatis, genital mycoplasmas.
VII week exercises	Diagnostics of sexually transmitted bacteria: Treponema palidum, Chlamydia trachomatis, genital mycoplasmas.
VIII week lectures	The microbiological control of pharmaceutical products: Principles of good manufacturing practices and methods to prevent contamination.
VIII week exercises	I semester practical exam (from I to VII week of practice).
IX week lectures	Medical mycology.
IX week exercises	Sampling and diagnostics: Candida, cutaneous mycoses, dermatomycoses , moldes.
X week lectures	Medical Parasitology: Protozoa and antiprotozoal agents.
X week exercises	Sampling and diagnostics in medical protozoology and parasitology.
XI week lectures	Medical Parasitology: nematode and cestode of the intestinal and tissue. Control test ( from I to XI week of practice).
XI week exercises	Diagnostics of viruses: cell culture, electron microscopy, hybridization techniques and serological reactions.
XII week lectures	Structure, replication and morphogenesis of the virus. Virological characteristics and medical significance of intestinal and respiratory viruses. HPV.
XII week exercises	Diagnostics of of intestinal, respiratory and HPV virus.
XIII week lectures	Paramyxoviridae and Orthomyxoviridae.
XIII week exercises	Diagnostics of hepatotropic, herpesviride and HIV viruses.
XIV week lectures	Virological characteristics and medical importance of the Herpesviridae family and HIV.
XIV week exercises	II semester practical exam (from IX to XIII week of practice)
XV week lectures	Hepatotropic viruses.
XV week exercises	Consultations for the final exam.

Student workload	Weekly: 4 credits x 40/30 = 5 hours and 20 minutes 2 hours of lectures 2 hours of exercises 1 hour and 20 minutes Individual work In the semester: Lectures and final exam: (5h 20 min) x 16 = 85h 20 min Necessary preparations (administration, enrolment, verification): 2 x 5 h 20 min = 10 h 40 min Cumulative course load: 4 x 30 = 120 h Additional work: preparation for correction exam period, including final exam up to 30h. Load structure: 85h 20 min+ 10 h 40 min + 20 h
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 2 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance at lectures, exercises, presentations of seminars, passing tests, practical and final exams.
Consultations	Tuesday 13:00 - 14:00 h.
Literature	Basic literature: Smilja Kalenić et al. Medical microbiology. Medical edition 2013 Zagreb. Additional literature: Medical Bacteriology, group of authors, editor Milena Švabić Vlahovic. Modern administration, Belgrade 2005. Medical Virology, Ljubisa Krstic
Examination methods	I. Before exams: 50 points. − Attendance at lectures/exercises: up to 10 points. − Seminar paper: up to 5 points. − Practical exam: up to15 points. − Control test: 10 to 20 points. II. Final exam: up to 50 points. Final exam provides possibility to defin
Special remarks
Comment	Additional information can be received by Chief of the Subject.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHISIOLOGY I

Course:

PHISIOLOGY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7611	Obavezan	3	6	3++2

Programs	PHARMACY
Prerequisites
Aims	Students will learn functional relationship among organ systems, regulatory and control mechanisms that govern adaptation of human body to changes in the internal and external environment.
Learning outcomes	After finishing the course and passing exam in Physiology 1, the student should achieve the following learning outcomes and should: 1. know the functions of organ systems, and how they interact in the organism as a whole. 2. be able to explain how physiological responses of organ systems relate to their anatomical and histological characteristics, and their biochemical status. 3. know regulatory and compensatory mechanisms that control the function of organ systems. 4. understand the logic and interpret cause and effect relationships in interactions between systems of organs. 5. know general mechanisms in the human body essential adaptation and survival. 6. master the appropriate medical terminology. 7. be able to use the acquired knowledge in relation to pharmacotherapy.
Lecturer / Teaching assistant	Doc. dr Nataša Popović
Methodology	This course uses Moodle as a web-based course management system. Teaching is conducted in the form of blended learning. We have face-to-face lectures, lab, seminar presentations, and consultations. They are combined with on-line and computer-mediated delivery of educational material, videos, lab simulations, and tests. Final evaluation is conducted as an oral exam.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to physiology. Homeostasis. Cell membrane. Transport of substances through the cell membrane. (Guyton, unit I and II)
I week exercises	Orientation.
II week lectures	Membrane potential. Action potential. Contraction of skeletal muscle. Excitation of the skeletal muscle. Excitation and contraction of the smooth muscle. (Guyton, unit II)
II week exercises	Red blood cells (RBC) in solutions of various osmotic concentrations. Osmotic resistance of RBC. (M. Drecun et al.)
III week lectures	Organization of the nervous system. CNS synapses and synaptic transmission. (Guyton, unit IX)
III week exercises	Physiology of excitable tissues. Resting membrane potential and action potential. Demonstration: making neuromuscular preparation. Differentiation of stimulation intensity in neuromuscular preparation. (M. Drecun et al.)
IV week lectures	Sensory receptors. Cortical processing of information. Somatic sensations: general organization. Pain. (Guyton, unit IX)
IV week exercises	Effects of the extracellular ion concentration and effects of local anesthetic on excitability of neuromuscular preparation. (M. Drecun et al.)
V week lectures	The eye - optics of vision. Receptor and neural function of retina. Central neurophysiology of vision. The senses of taste and smell. (Guyton, unit XI)
V week exercises	Test 1.
VI week lectures	The senses of hearing and balance. Central motor and integrative neurophysiology. Motor functions of the spinal cord, the spinal cord reflexes. (Guyton, unit XI)
VI week exercises	Simple and complex muscle contraction. Effects of myorelaxing agents on functioning of neuromuscular preparation. (M. Drecun et al.)
VII week lectures	The autonomic nervous system and adrenal medulla- part one. Cortical and brain stem control of motor function. (Guyton, unit XI)
VII week exercises	The eye-optics of vision. Visual acuity. (M. Drecun et al.)
VIII week lectures	The autonomic nervous system and adrenal medulla- part-two. (Guyton, unit XI)
VIII week exercises	Reflexes- general principles and definitions. Spinal shock. Spinal reflexes of a frog. (Đ. Sterio et al.)
IX week lectures	Contributions of the basal ganglia and cerebellum to overall motor control (Guyton, unit XI)
IX week exercises	Review.
X week lectures	Cerebral cortex, intellectual functions of the brain, learning and memory (Guyton, unit XI)
X week exercises	Review.
XI week lectures	Behavioral and motivational mechanisms of the brain- the limbic system and the hypothalamus. States of brain activity and sleep. (Guyton, unit XI)
XI week exercises	Review.
XII week lectures	Seminar.
XII week exercises	Test 2.
XIII week lectures	Seminar.
XIII week exercises	Review lab.
XIV week lectures	Seminar.
XIV week exercises	Make up tests 1 and 2.
XV week lectures	Review.
XV week exercises	Review.

Student workload
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 3 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of face-to-face lectures, seminars and labs. Showing adequate knowledge improvement after each lab. Taking 2 tests during the semester.
Consultations	As arranged with the instructor.
Literature	1) Medicinska fiziologija. Guyton & Hall. Publisher : Savremena administracija, Beograd, 12th edition 2) Praktikum iz fiziologije. M. Drecun et al. Publisher: Papirus Zvornik, 2003. 3) Praktikum iz fiziologije. Đ. Sterio et al. Publisher: Medicinski fa
Examination methods	Attendance of lectures- 7 points. Attendance of lab with verification of knowledge improvement after each lab -9 points. Two tests -30 points. Seminar presentation -3 points. Registration on Moodle -1 point. Final exam (lab + oral exam) –50 points
Special remarks	None.
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ANALYTICAL CHEMISTRY II

Course:

ANALYTICAL CHEMISTRY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5952	Obavezan	3	8	3++3

Programs	PHARMACY
Prerequisites	Analytical chemistry I
Aims	Mastering the basics of laboratory work in quantitative analysis in order to enable students to solve analytical problems. Analytical application of classical and quantitative analysis of selected instrumental methods in the analysis of inorganic ions. Assessment, processing and interpretation of results
Learning outcomes	1.Estimate the quantitativeness of reactions for determing analytes; 2. Calculate and construct a titration curve; 3. Explain and properly select indicators for the corresponding titration systems; 4. Select the method based on the ion to be determined; 5. Perform all phases of a quantitative chemical analysis, process, interpret and assess the results.
Lecturer / Teaching assistant	Professor Vesna Vukašinović-Pešić, PhD
Methodology	Lectures, laboratory exercises with computation exercises, assessment processing and interpretation of results, consultation

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Basic principles of quantitative chemical analysis
I week exercises	Introduction. Familiarizing the students with the laboratory settings. Literature
II week lectures	Gravimetric analysis.
II week exercises	Gravimetric determination of Fe
III week lectures	Volumetric analysis. Titration in aqueous and non-aqueous medium; standard solutions; indicators
III week exercises	Gravimetric determination of Fe
IV week lectures	Acid-base titrations of monoprotic and polyprotic systems.
IV week exercises	Acid-base titrations
V week lectures	Precipitation titrations. Test I
V week exercises	Examples of acid-base titrations
VI week lectures	Complexometric titrations
VI week exercises	Precipitation titrations
VII week lectures	Oxido-reduction titrations
VII week exercises	I colloquium
VIII week lectures	Oxido-reduction titrations, method of permanganometry. I colloquium (additional offering)
VIII week exercises	Complexometric titrations
IX week lectures	Oxido-reduction titrations, method of iodometry
IX week exercises	Permanganometric determination of Fe
X week lectures	Oxido-reduction titrations, bromatometry, dichromatometry
X week exercises	Iodometric determination of Cu
XI week lectures	Computational exercises
XI week exercises	Iodometric determination ascorbic acid and As(III)-oxide
XII week lectures	Electroanalytical methods. Test II
XII week exercises	II colloquium
XIII week lectures	Potentiometric
XIII week exercises	Potentiometric determination of phosphoric acid
XIV week lectures	Electrogravimetric
XIV week exercises	II colloquium (additional offering)
XV week lectures	Preparation for the exam
XV week exercises	Final exam

Student workload
Per week	Per semester
8 credits x 40/30=10 hours and 40 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 4 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 10 hour(s) i 40 minuts x 16 =170 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 10 hour(s) i 40 minuts x 2 =21 hour(s) i 20 minuts Total workload for the subject: 8 x 30=240 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 48 hour(s) i 0 minuts Workload structure: 170 hour(s) i 40 minuts (cources), 21 hour(s) i 20 minuts (preparation), 48 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend lectures, as well as doing tests, completed all laboratory exercises and both colloquiums.
Consultations
Literature	1. D.A.Skog,D.M.West and F.J.Holer ,Fundaments of Analitical Chemistry,6 edition,Suanders Colege Publishing,A.Harco-urt Brase Jovanovich College Publisher,1996.. ;2. M.Jelikić-Stankov,V.Kapetanović i dr. Kvantitativna hemijska analiza, praktikum zbirka z
Examination methods	Tests (0-5+0-5 poens); Laboratory exercises (0 -10 poens ); Colloquiums ( 0 - 30 poens), Final exam (0 - 50 poens)
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE II

Course:

ENGLISH LANGUAGE II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
2094	Obavezan	4	2	2+1+0

Programs	PHARMACY
Prerequisites	None.
Aims	Acquiring the skills of understanding the spoken and written English dealing with medicine and pharmacy. Upgrading language skills
Learning outcomes	At the end of this course student will be able to: - communicate in English in the context of professional use - work in English as a medical professional - use words and expressions in the field of research and various phases of drug production - gain knowledge on specialist vocabulary related to production, packaging and drug distribution - use words and expressions related to basic medical investigations, medical and surgical treatment - recognize and use words and expressions related to body systems, common diseases and symptoms.
Lecturer / Teaching assistant	Prof. dr Nataša Kostić, dr Dragana Čarapić
Methodology	Lectures and discussions.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Giving results
I week exercises	Laboratory safety systems
II week lectures	Explaining medical terminology to a patient and giving prognosis
II week exercises	Standard operating procedures
III week lectures	Planning treatment and closing the interview
III week exercises	Drug contamination: Lessons to be learned?
IV week lectures	Describing benefits and side effects and advising on lifestyle
IV week exercises	Ready for testing in live organisms
V week lectures	Role play: explaining, negotiating treatment and closing the interview (group I)
V week exercises	Preclinical testing
VI week lectures	Role play: explaining, negotiating treatment and closing the interview (group II)
VI week exercises	Clinical testing
VII week lectures	Dealing with sensitive issues
VII week exercises	Mid-term test
VIII week lectures	Reading and responding to patient cues
VIII week exercises	Dealing with authorities
IX week lectures	Employing question techniques: CAGE
IX week exercises	Experimental drugs on trial
X week lectures	Breaking bad news
X week exercises	Remedial mid-term test
XI week lectures	Reassuring a patient or relative and showing sympathy
XI week exercises	Drug safety and regulatory affairs
XII week lectures	Role play: delivering bad news, reassuring the patient and showing empathy (group I)
XII week exercises	Pharmacovigilance
XIII week lectures	Role play: delivering bad news, reassuring the patient and showing empathy (group II)
XIII week exercises	Regulatory documentation
XIV week lectures	Communicating with challenging patients
XIV week exercises	Counterfeit medicines
XV week lectures	Receiving an uncommunicative patient, interviewing an irritated patient, dealing with a manipulative patient
XV week exercises	Final exam – mock test

Student workload
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises -1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Students are obliged to attend the classes, participate in discussions, do tasks and take tests
Consultations	kostic@ucg.ac.me
Literature	1. McCullagh M, Wright R. Good Practice: Communication Skills in English for the Medical Practitioner. Cambridge: Cambridge University Press; 2008. 2. Buchler M, Jaehnig K, Matzig G, Weindler T. English for the Pharmaceutical Industry. Oxford: Oxford University Press; 2010. 3. Oxford Concise Medical Dictionary. Oxford: Oxford University Press; 2003. 4. Mićić S. Medicinski rečnik. Beograd: Zavod za udžbenike; 2007
Examination methods	Mid-term exam: 40 points, Presentation: 10 points, Final exam: 50 points
Special remarks	-
Comment	The lectures are taught in English and Montenegrin.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE II

Course:

ENGLISH LANGUAGE II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
2094	Obavezan	4	2	2+1+0

Programs	PHARMACY
Prerequisites	None.
Aims	Acquiring the skills of understanding the spoken and written English dealing with medicine and pharmacy. Upgrading language skills
Learning outcomes	At the end of this course student will be able to: - communicate in English in the context of professional use - work in English as a medical professional - use words and expressions in the field of research and various phases of drug production - gain knowledge on specialist vocabulary related to production, packaging and drug distribution - use words and expressions related to basic medical investigations, medical and surgical treatment - recognize and use words and expressions related to body systems, common diseases and symptoms.
Lecturer / Teaching assistant	Prof. dr Nataša Kostić, dr Dragana Čarapić
Methodology	Lectures and discussions.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Giving results
I week exercises	Laboratory safety systems
II week lectures	Explaining medical terminology to a patient and giving prognosis
II week exercises	Standard operating procedures
III week lectures	Planning treatment and closing the interview
III week exercises	Drug contamination: Lessons to be learned?
IV week lectures	Describing benefits and side effects and advising on lifestyle
IV week exercises	Ready for testing in live organisms
V week lectures	Role play: explaining, negotiating treatment and closing the interview (group I)
V week exercises	Preclinical testing
VI week lectures	Role play: explaining, negotiating treatment and closing the interview (group II)
VI week exercises	Clinical testing
VII week lectures	Dealing with sensitive issues
VII week exercises	Mid-term test
VIII week lectures	Reading and responding to patient cues
VIII week exercises	Dealing with authorities
IX week lectures	Employing question techniques: CAGE
IX week exercises	Experimental drugs on trial
X week lectures	Breaking bad news
X week exercises	Remedial mid-term test
XI week lectures	Reassuring a patient or relative and showing sympathy
XI week exercises	Drug safety and regulatory affairs
XII week lectures	Role play: delivering bad news, reassuring the patient and showing empathy (group I)
XII week exercises	Pharmacovigilance
XIII week lectures	Role play: delivering bad news, reassuring the patient and showing empathy (group II)
XIII week exercises	Regulatory documentation
XIV week lectures	Communicating with challenging patients
XIV week exercises	Counterfeit medicines
XV week lectures	Receiving an uncommunicative patient, interviewing an irritated patient, dealing with a manipulative patient
XV week exercises	Final exam – mock test

Student workload
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises -1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Students are obliged to attend the classes, participate in discussions, do tasks and take tests
Consultations	kostic@ucg.ac.me
Literature	1. McCullagh M, Wright R. Good Practice: Communication Skills in English for the Medical Practitioner. Cambridge: Cambridge University Press; 2008. 2. Buchler M, Jaehnig K, Matzig G, Weindler T. English for the Pharmaceutical Industry. Oxford: Oxford University Press; 2010. 3. Oxford Concise Medical Dictionary. Oxford: Oxford University Press; 2003. 4. Mićić S. Medicinski rečnik. Beograd: Zavod za udžbenike; 2007
Examination methods	Mid-term exam: 40 points, Presentation: 10 points, Final exam: 50 points
Special remarks	-
Comment	The lectures are taught in English and Montenegrin.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / GENERAL BIOCHEMISTRY

Course:

GENERAL BIOCHEMISTRY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5961	Obavezan	4	4	3+1+0

Programs	PHARMACY
Prerequisites
Aims
Learning outcomes	1. Explain the structure and function of carbohydrates, proteins, lipids, and nucleotides; 2. Define the structure and mechanisms of action of enzymes; 3. Explain the structure and role of the cell membrane; 4. Understand the catabolism of lipids, carbohydrates and nitrogen compounds; 5. Compare the anabolism of lipids, nitrogen compounds and carbohydrates; 6. Identify and analyze the intercellular signalisation and biotransformation; 7. Understand the importance of the biosynthesis of proteins and nucleic acids.
Lecturer / Teaching assistant
Methodology

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures
I week exercises
II week lectures
II week exercises
III week lectures
III week exercises
IV week lectures
IV week exercises
V week lectures
V week exercises
VI week lectures
VI week exercises
VII week lectures
VII week exercises
VIII week lectures
VIII week exercises
IX week lectures
IX week exercises
X week lectures
X week exercises
XI week lectures
XI week exercises
XII week lectures
XII week exercises
XIII week lectures
XIII week exercises
XIV week lectures
XIV week exercises
XV week lectures
XV week exercises

Student workload
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations
Consultations
Literature
Examination methods
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHISIOLOGY II

Course:

PHISIOLOGY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7612	Obavezan	4	4	2++2

Programs	PHARMACY
Prerequisites
Aims	Students will learn functional relationship among organ systems, regulatory and control mechanisms that govern adaptation of human body to changes in the internal and external environment.
Learning outcomes	After finishing the course and passing exam in Physiology 1, the student should achieve the following learning outcomes and should: 1. know the functions of organ systems, and how they interact in the organism as a whole. 2. be able to explain how physiological responses of organ systems relate to their anatomical and histological characteristics, and their biochemical status. 3. know regulatory and compensatory mechanisms that control the function of organ systems. 4. understand the logic and interpret cause and effect relationships in interactions between systems of organs. 5. know general mechanisms in the human body essential adaptation and survival. 6. master the appropriate medical terminology. 7. be able to use the acquired knowledge in relation to pharmacotherapy.
Lecturer / Teaching assistant	Doc. dr Mihailo Vukmirović
Methodology	This course uses Moodle as a web-based course management system. Teaching is conducted in the form of blended learning. We have face-to-face lectures, lab, seminar presentations, and consultations. They are combined with on-line and computer-mediated delivery of educational material, videos, lab simulations, and tests. Final evaluation is conducted as an oral exam.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	RBC. Blood types. Hemostasis. (Guyton, unit VI)
I week exercises	Orientation.
II week lectures	Immune system: innate and specific immunity. (Guyton, unit VI)
II week exercises	Red blood cell cont. Sedimentation. Hematocrit and hematological indices. (M. Drecun et al.)
III week lectures	Respiration: mechanics of pulmonary ventilation. Functions of respiratory passages, reflex of cough and sneeze. Pulmonary volumes and capacities. Alveolar ventilation, circulation of blood in the lung. Respiratory membrane and gas exchange. Solubility of
III week exercises	Hemostasis. Blood types. (Đ. Sterio et al.)
IV week lectures	Transport of oxygen from the lungs to body tissues. Dissociation of oxyhemoglobin. Transport of CO2. Acid- base balance. Regulation of respiration. Respiration during the exercise, and at the high altitude. (Guyton, unit VII and VIII)
IV week exercises	White blood cell count. White blood cell differential count. (M. Drecun et al.)
V week lectures	Physiology and organization of cardiovascular system (CVS). Heart as a pump. Conduction system of the heart. Action potential of the cardiac muscle cell. Electrocardiogram (ECG). (Guyton, unit III)
V week exercises	Test 3.
VI week lectures	Heart cycle. Heart sounds. Polycardiogram. Stroke volume, cardiac output, and their regulation. Hemodynamics. Pressure, flow and resistance. Viscosity and hematocrit. (Guyton, unit III and IV)
VI week exercises	Mechanics of pulmonary ventilation. Respiratory volumes and capacities. Spirometry. (M. Drecun et al. )
VII week lectures	Overview of circulation. Blood pressure. Capillary pressure. Interstitial fluid. (Guyton, Unit IV)
VII week exercises	ECG- registration and analysis. (M. Drecun et al.)
VIII week lectures	Neural and humoral control of blood flow. Sympathetic nervous system in the control of blood distribution. Cardiac output, venous return. Rapid control of blood pressure. (Guyton, unit IV)
VIII week exercises	Heart auscultation. Phonocardiogram. (M. Drecun et al.)
IX week lectures	Kidney, nephron, basic principles of function. Glomerular filtration and its regulation. Tubular reabsorption. Peritubular vascular network. Henley s loop. Concentration and dilution of tubular fluid. (Guyton, unit V)
IX week exercises	Carotidogram. Polycardiogram. (M. Drecun et al.)
X week lectures	Role of kidneys in maintenance of extracellular fluid volume. Long term control of blood pressure. Regulation of extracellular fluid osmolarity. Acid-base regulation. (Guyton, units IV and V)
X week exercises	Measuring blood pressure. (M. Drecun et al.)
XI week lectures	Energetics. Formation of ATP. Metabolism. Physiology of gastrointestinal tract (GIT), structure and function. Motility and enteric plexus. (Guyton, units XII, XIII)
XI week exercises	Test 4.
XII week lectures	Secretion, digestion and absorption in GIT. (Guyton, unit XII)
XII week exercises	Clearance. Metabolism of medications. (Đ. Sterio et al.)
XIII week lectures	Endocrinology. Mechanisms of action of hormones. Regulation of hormone secretion. Pituitary hormones and their control by hypothalamus. Growth hormone. Adrenocortical hormones. Stress. Thyroid hormone. (Guyton, unit XIV)
XIII week exercises	Review lab.
XIV week lectures	Sex hormones. Insulin, glucagon- endocrine pancreas. Hormones in regulation of metabolism of Ca++ and phosphates. (Guyton, unit XIV)
XIV week exercises	Test 5.
XV week lectures	Review.
XV week exercises	Make up tests 3, 4 and 5.

Student workload
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of face-to-face lectures, seminars and labs. Showing adequate knowledge improvement after each lab. Taking 3 tests during the semester.
Consultations	As arranged with the instructor.
Literature	1) Medicinska fiziologija. Guyton & Hall. Publisher : Savremena administracija, Beograd, 12th edition 2) Praktikum iz fiziologije. M. Drecun et al. Publisher: Papirus Zvornik, 2003. 3) Praktikum iz fiziologije. Đ. Sterio et al. Publisher: Medicinski fa
Examination methods	Attendance of lectures- 7 points. Attendance of lab with verification of knowledge improvement after each lab -13 points. Three tests -30 points. Registration on Moodle -1 point. Final exam (lab + oral exam)- 50 points.
Special remarks	None.
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL CHEMISTRY I

Course:

PHARMACEUTICAL CHEMISTRY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5960	Obavezan	4	5	3++1

Programs	PHARMACY
Prerequisites	Organic Chemistry II
Aims	The aim is for the student to acquire basic knowledge of pharmaceutical-medical chemistry that will be useful for mastering the material in Pharmaceutical Chemistry II, Pharmaceutical Chemistry III, Pharmacology, and Pharmacokinetics. In addition to the basic chemical characterization of drugs, the course enables students to master digital tools for analyzing and interpreting chemical data, as well as working with chemical and pharmaceutical information databases.
Learning outcomes	After attending the lectures and exercises, students will be able to: Predict the physicochemical properties of pharmacologically active molecules based on the knowledge of structural formulas; Assess chemical and metabolic stability; Understand, at the molecular level, the target sites and mechanisms of drug action; Analyze the relationships between chemical structure, properties, and drug effects; Explain the significance of drug structure modifications (prodrug design and isosteric replacements); Use digital chemical tools for research, interpretation, and prediction of pharmaceutical substance properties.
Lecturer / Teaching assistant	PharmD, PhD, Nemanja Turković,
Methodology	teaching, practical work, colloquia

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to Pharmaceutical-Medical Chemistry and Physicochemical Characterization of Drugs – Acid-Base Properties of Drugs
I week exercises	Computer Exercises: Electronic Databases Relevant to Pharmaceutical Chemistry and Pharmacy – Data Searching and Analysis
II week lectures	Physicochemical Characterization of Drugs – Lipophilicity, Solubility, and Permeability
II week exercises	Application of Electronic Databases for Pharmacophores and Chemical Structures – Computer Exercises
III week lectures	Overview of Functional Groups Relevant to Drug Chemistry
III week exercises	Exercises: Functional Groups and Physicochemical Properties of Medicinal Substances (Acid-Base Properties, Solubility, Lipophilicity)
IV week lectures	Chemical Stability of Drugs (In Vitro Stability)
IV week exercises	Use of Software for Molecular Modeling and Structural Formula Analysis – Computer Exercises
V week lectures	Drug Biotransformation Reactions / Drug Metabolism (In Vivo Stability)
V week exercises	Computer Exercises: Software Tools for Predicting In Vitro Chemical Stability of Drugs Based on Chemical Structure
VI week lectures	Physicochemical properties, chemical instability, and metabolic reactions undergone by compounds with characteristic functional groups and heterocycles
VI week exercises	Computer Exercises: Software Tools for Predicting In Vitro Chemical Stability of Drugs Based on Chemical Structure
VII week lectures	Drug Target Sites: Enzymes
VII week exercises	Exercises: Predicting Drug Metabolism Based on Chemical Structure
VIII week lectures	Drug Target Sites: Receptors
VIII week exercises	Exercises: Predicting Drug Metabolism Based on Chemical Structure
IX week lectures	Mechanisms of Drug Action
IX week exercises	Exercises: Drug Target Sites
X week lectures	Structure-Activity Relationships (SAR) of Drugs
X week exercises	Computer Exercises: SAR Analysis – Structure-Activity and Prediction of Biological Activity Using Software Tools
XI week lectures	Quantitative Structure-Activity and Structure-Property Relationships (QSAR and QSPR)
XI week exercises	Computer Exercises: QSAR Analysis – Quantitative Correlation of Structural Parameters and Biological Activity Using Software Tools
XII week lectures	Prodrugs
XII week exercises	Exercises: Computer Programs Used in Pharmaceutical Chemistry (Drawing Formulas, 3D Models, Descriptors)
XIII week lectures	Bioisosteres
XIII week exercises	Exercises: Calculation of logP, logD, and pKa Using Computer Programs
XIV week lectures	Bioisosteres
XIV week exercises	Exercises: Computer Programs Used in Pharmaceutical Chemistry (Drawing Formulas, 3D Models, Descriptors)
XV week lectures	Calculation of logP, logD, and pKa Using Computer Programs
XV week exercises	Review of Material and Exam Preparation Exercises: Review of Material and Exam Preparation

Student workload	3 hours lectures, 1 hour practical work and 1 ,66 hour student independent work including consulting. Week: 6,66 hours. Semester: 150 hours.
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 3 sat(a) theoretical classes 1 sat(a) practical classes 0 excercises 2 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance in lectures and practical work
Consultations
Literature	1. Molecular ConceptorTM www.molecular-conceptor.com 2. Graham L. Patrick, An Introduction to Medicinal Chemistry Oxford University Press, second edition, 2001. 3. David A. Wiliams, Thomas L. Lemke, Foye‘s Principles of Medicinal Chemistry Lippincott Williams & Wilkins, fifth edition, 2002. 4. Donald Cairns, Essentials of Pharmaceutical ChemistryPharmaceutical Press, 2002.
Examination methods	Attendance in theoretical and practical classes: 0–10 points; Participation in practical classes: 0–20 points; Colloquium: 0–20 points; Final exam: 0–50 points. A passing grade is awarded if a minimum of 50 points is accumulated in total.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / INSTRUMENTAL METHODS

Course:

INSTRUMENTAL METHODS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5957	Obavezan	4	6	3++3

Programs	PHARMACY
Prerequisites	There are no prerequisites for registering and taking courses.
Aims	Students get to know the theoretical principles, apparatus, method of execution and possibilities of application of various instrumental methods. The emphasis is on the application of methods that are most often used in laboratory practice.
Learning outcomes	1. Apply the theoretical knowledge related to the instrumental methods of analysis (spectrometry, thermal methods, instrumental methods of separation, electroanalytical methods...) and principles of instrument operation; 2. Interpret the adopted theoretical knowledge about the instrumental methods of analysis and principles of instrument operation; 3. Use the appropriate instrumental method with respect to the characteristics of the analyte and the specificities of the sample; 4. Apply the knowledge and independently perform an experiment following the instructions, 5. Demonstrate the results of experimental analysis.
Lecturer / Teaching assistant	Full professor Nada Blagojević; Associate Snežana Vukanović, PhD
Methodology	Teaching method and mastering the material Lectures, laboratory exercises. Independent study. Consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Principles of spectral analysis. Absorption in the visible part of the spectrum.
I week exercises	Preparation for spectrophotometric measurements and work with a UV-VIS spectrophotometer
II week lectures	Colorimetric, photometric and spectrophotometric methods.
II week exercises	Determination of iron content in drinking water using the Heliga comparator.
III week lectures	Emission spectral analysis. Fluorimetry. Atomic absorption spectroscopy.
III week exercises	Determination of iron content in the form of Fe(CNS)3.
IV week lectures	Atomic fluorescence spectroscopy. (Nephelometry and turbidimetry - report)
IV week exercises	Photometric titration of Cu(II)-Ca(II) mixture.
V week lectures	Refractometry. Polarimetry. Thermometry. - report
V week exercises	Determination of the working wavelength of Cr(III).
VI week lectures	Mass spectrometry.
VI week exercises	Determination of unknown Cr(III) concentration. Colloquium
VII week lectures	Nuclear magnetic resonance.
VII week exercises	Determination of the molar absorption coefficient of the color malachite green.
VIII week lectures	Infrared spectroscopy.
VIII week exercises	Determination of urea by IR analysis. Remedial colloquium
IX week lectures	Ultraviolet spectroscopy.
IX week exercises	Determination of zinc content in drinking water using the AAS method
X week lectures	Separation methods. Column chromatography. Chromatography on paper. Thin-layer chromatography.
X week exercises	Determination of metal content in multivitamin preparations.
XI week lectures	Gas chromatography. Liquid chromatography.
XI week exercises	Determination of vitamin C
XII week lectures	Electrophoresis. - report
XII week exercises	Thin layer chromatography. Getting to know the operation of GH and HPLC chromatographs.
XIII week lectures	Conductometry. Polarography. - report
XIII week exercises	Reports
XIV week lectures	Stripping voltammetry. Cyclic voltammetry. Coulometry. - report
XIV week exercises	Cyclic voltammetry and compensation
XV week lectures	Final exam.
XV week exercises

Student workload
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend classes, to do and defend laboratory exercises, to do colloquiums and reports.
Consultations	Consultations as needed, according to the agreement of the students with the teacher and associate
Literature	1. M. Medenica, N. Pejić, Instrumental methods, University of Belgrade, 2018. 2. D. Manojlović, J. Mutić, D. Šegan, Fundamentals of electroanalytical chemistry, University of Belgrade, 2010. 3. T. Verbić, M. Pešić, N. Obradović, I. Cvijetić, Praktikum with a collection of problems from instrumental analytical chemistry (optical and electroanalytical methods), University of Belgrade, 2018. 4. D. A. Skog, D. M. West and F. J. Holer, Fundaments of Analytical Chemistry, 2021.
Examination methods	- class activities and report (14 points) (4+10) - colloquium (30 points) - laboratory exercise activities: (6 points), - final exams: (50 points).
Special remarks	In order for a student to take the exam, he must have completed and certified all laboratory exercises
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOGNOSY I

Course:

PHARMACOGNOSY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5959	Obavezan	4	6	2++3

Programs	PHARMACY
Prerequisites	Botany
Aims	Acquiring knowledge about pharmacologically active ingredients of natural origin that belong to the group secondary and primary metabolites of plants and animals. In addition to getting acquainted with the most important chemical groups of compounds, their structure, properties and pharmacological activity, students are introduced through theoretical and practical teaching indicates the most important methods of their qualitative and quantitative analysis in plant material. Also, students get to know the most important plant raw materials that are used for extraction of plant compounds that are used today in the form of pure substances for the production of medicines.
Learning outcomes	After attending lectures and exercises, students will acquire knowledge and skills about: 1. secondary and primary plant metabolites; 2. chemical composition of herbal drugs, structures of active principles, their pharmacological effects and biosynthesis of secondary metabolites (alkaloids, heterosides, saponosides, terpenoids, lipids-fatty substances, natural waxes) and primary metabolites (carbohydrates and polysaccharide); 3. the most important plant raw materials, which are biological sources for the mentioned chemicals structures; 4. methods of isolation of active principles 5. selection of the most important methods for qualitative i quantitative analysis of plant raw materials; Using the acquired knowledge, students will master the skills for independent analysis of plant raw materials.
Lecturer / Teaching assistant	Dr sci. med. Miloš Krivokapić
Methodology	Interactive lectures, practical classes, seminars, colloquium, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Interactive lectures, practical classes, seminars, colloquium, consultations.
I week exercises	Examining the general quality (correctness) of drugs.
II week lectures	Basic methods of qualitative and quantitative analysis of active metabolites.
II week exercises	Examining the quality of drugs using basic qualitative and quantitative analyses.
III week lectures	Structure, analysis, isolation and pharmaceutical importance: alkaloids of ornithine and lysine derivatives, nicotinic acid.
III week exercises	Qualitative analysis (proving) of alkaloids.
IV week lectures	Structure, analysis, isolation and pharmaceutical importance: phenylalanine derivative alkaloids.
IV week exercises	Isolation and proof of alkaloids.
V week lectures	Structure, analysis, isolation and pharmaceutical importance: tryptophan derivative alkaloids, histidine; Steroidal and terpene alkaloids.
V week exercises	Colorimetric determination of secale cornutum alkaloids.
VI week lectures	Structure of other metabolites synthesized from amino acids (cyanohydrins, glucosinolates, lectins). Secondary metabolites of the phenylpropane biosynthetic pathway (phenols, polyphenols, phenolic acids, coumarin, lignan, flavonoid, tannin). Colloquium I.
VI week exercises	Proving heterosidence.
VII week lectures	Polyphenolic ingredients produced by the polyketide biosynthetic pathway (naphthoquinones, anthranoids, naphthodianthrones).
VII week exercises	Proving heterosidence.
VIII week lectures	Secondary metabolites of the isoprene biosynthetic pathway (monoterpenes, sesquiterpenes, diterpenes, triterpenes, tetraterpenes and polyterpenes). Essential oils and aromatic plants.
VIII week exercises	Extraction of essential oils. Qualitative and quantitative analysis of essential oils.
IX week lectures	Steroid compounds of plants. Cardiodonic heterosides. Primary metabolites: monosaccharides, polysaccharides, heteropolysaccharides; fatty acids, fatty oils, waxes, polyacetylenes.
IX week exercises	Cardiotonic heterosides.
X week lectures	Raw materials for the extraction of alkaloids.
X week exercises	Examination of the value of bitter drugs.
XI week lectures	Raw materials for the extraction of alkaloids. Colloquium from the theoretical part of the material.
XI week exercises	Demonstration of saponin and determination of the value of saponin drugs.
XII week lectures	Raw materials for the extraction of alkaloids.
XII week exercises	Qualitative and quantitative analysis of tannic drugs.
XIII week lectures	Raw materials for the extraction of cardiotonic heterosides. Colloquium from the practical part of the material.
XIII week exercises	Spectrophotometric determination in combination with the precipitation of tannins with leather powder.
XIV week lectures	Raw materials for the extraction of other steroids. Raw materials for lignan extraction.
XIV week exercises	Additional analyzes of essential oils.
XV week lectures	Final exam.
XV week exercises	Make up from the final exam.

Student workload	In the semester Classes and final exam 8.40 hours x 16 = 134.4 hours. Necessary preparations before the beginning of the semester (registration, certification...) 8.40 x2 = 16.8 hours. Total load: 6 x 30= 180 h Additional work 28.8 h Load structure: 134.4 hours (teaching) + 16.8 hours (preparation) + 28.8 hours (additional work) = 180 hours.
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 2 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises.
Consultations	Consultations take place by agreement with students.
Literature	1. Kovačević N. Basics of pharmacognosy. Serbian school book, Belgrade, 2002. 2. Gorunović M., Lukić P.: Pharmacognosy. Faculty of Pharmacy Belgrade, 2001. 3. Bruneton, J. Pharmacognosy, Phytochemistry, Medicinal Plants, 2nd ed. Lavoisier Publishing, Paris, 1999. 4. Hänsel R, Sticher O, Steinegger E. Pharmacognosie-Phytopharmazie. Berlin, Heidelberg: Springer-Verlag, 1999. 5. Petrović S, Maksimović Z, Kundaković T. Analysis of ingredients herbal drugs. Faculty of Pharmacy, Belgrade, 2009. 6. Kundaković T, Drobac M, Petrović S, Maksimović Z, Marchetić M. Macroscopic and microscopic analysis of herbal drugs. Faculty of Pharmacy, Belgrade, 2017. 7. Petrović S, Maksimović Z, Kundaković T. Chemical analysis of herbal drugs and ingredients. Faculty of Pharmacy, Belgrade, 2013.
Examination methods	Activities during lectures, assessment of practical classes, presentations, seminar papers, colloquium, final exam. Pre-examination requirements: 50 points; Attendance at lectures (0-5) points; Exercise activity and preparation exercises (0-15); Colloquium from the theoretical part of the material (0-10 points); Colloquium from the practical part of the material (0-20 points). Final exam: 0-50 points A passed exam implies a cumulative total of 50 points and more.
Special remarks	Theoretical teaching takes place for all students together, practical teaching in groups of no more than 15 students.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL BIOCHEMISTRY

Course:

PHARMACEUTICAL BIOCHEMISTRY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
11859	Obavezan	4	7	4++2

Programs	PHARMACY
Prerequisites
Aims
Learning outcomes
Lecturer / Teaching assistant
Methodology

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures
I week exercises
II week lectures
II week exercises
III week lectures
III week exercises
IV week lectures
IV week exercises
V week lectures
V week exercises
VI week lectures
VI week exercises
VII week lectures
VII week exercises
VIII week lectures
VIII week exercises
IX week lectures
IX week exercises
X week lectures
X week exercises
XI week lectures
XI week exercises
XII week lectures
XII week exercises
XIII week lectures
XIII week exercises
XIV week lectures
XIV week exercises
XV week lectures
XV week exercises

Student workload
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 4 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations
Consultations
Literature
Examination methods
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / DIETETICS

Course:

DIETETICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7629	Obavezan	5	2	1+1+0

Programs	PHARMACY
Prerequisites	None
Aims	Providing information regarding the existing guidances, recommendations and other tools used to design dietary regimens; information of specific nutritive needs for certain age groups and during the course of therapy or prevention of illnesses; information on specific groups of dietary products.
Learning outcomes	Student is capable to provide appropriate interpretation of dietary recommendations; to give general advice on the healthy nutrition of the general population as well as advices on nutrition to patients suffering from noncontagious illnesses whose nutrition serves as a co-therapy; to provide basic information on dietary products, and food and drugs interactions.
Lecturer / Teaching assistant	Dejan Jancic, PhD
Methodology	Lectures, workshops, seminars

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to subject; definitions of basic terms.
I week exercises	Understanding the roles and activities of pharmacists in dietary interventions
II week lectures	The role of food
II week exercises	Calculation of energy value of foods
III week lectures	Energy needs of people, methods for estimating energy needs
III week exercises	Calculating energy needs on examples
IV week lectures	Other nutritional needs, recommendations for daily intake of macro and micronutrients
IV week exercises	Calculating the participation of fats, carbohydrates and proteins in total daily energy consumption
V week lectures	Tools for implementing optimal and balanced nutrition
V week exercises	Methods for assessing diet quality and nutrition status
VI week lectures	Basics of nutritional epidemiology
VI week exercises	Examples of using the tables of food ingredients
VII week lectures	Biologically active food ingredients
VII week exercises	Seminar
VIII week lectures	Nutrition in the prevention and treatment of chronic noncontagious illnesses
VIII week exercises	Seminar
IX week lectures	Sports nutrition
IX week exercises	Seminar
X week lectures	Allergies and intolerances to food ingredients
X week exercises	Seminar
XI week lectures	Nutritional deficits
XI week exercises	Seminar
XII week lectures	Food and drugs interactions
XII week exercises	Seminar
XIII week lectures	Dietary supplements
XIII week exercises	Interpretation of information about dietary products
XIV week lectures	Dietary products and food fortification
XIV week exercises	Analysis of the energy and nutritive value of dietary products
XV week lectures	The role of pharmacists in informing the population about the basics of proper nutrition
XV week exercises	Seminar

Student workload	On weekly basis: 2 credits x 40/30 = 2.6 hours. Structure: 1 hour of lectures, 1 hours of practice work; 1 hour of individual work
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 0 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Lectures attendance (0 – 10 points); Practical work (0 – 20 points); Seminar (0 – 20 points); Final exam from laboratory work (0 – 15 points); final exam (0 – 50 points).
Consultations
Literature	Present knowledge of nutrition", editori EE. Ziegler, LJ Filer, ILSI Press, Washington DC, 1996; "Encyclopedia
Examination methods	Lectures attendance (0 – 10 points); Practical work (0 – 20 points); Seminar (0 – 20 points); Final exam from laboratory work (0 – 15 points); final exam (0 – 50 points). The pass grade for the exam is obtained if the student accumulates at least 50 po
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PATHOPHYSIOLOGY

Course:

PATHOPHYSIOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6769	Obavezan	5	4	2+1+0

Programs	PHARMACY
Prerequisites	no conditionality
Aims	Acquisition of knowledge about the disease etiopathogenesis, the most important causes and mechanisms of damage to cells and tissues, the most important clinical manifestations of metabolic disorders, introduction to the diagnostic significance of clinical and laboratory tests and analysis, the adoption of basic medical terminology
Learning outcomes	1. Understand the basic medical terminology; 2. Properly and adequately reproduce medically relevant facts; 3. Understand the etiology and pathogenesis of the basic metabolic and functional disorders of the human organs and organ systems and be able to find the link between the clinical manifestations and the causes and origination mechanisms; 4. Understand the mechanisms of action of chemical agents and drugs; 5. Know the pathobiological basis for diagnostic strategy for pathologies.
Lecturer / Teaching assistant	Prof. Dr. Milica Martinovic and associates from the Faculty of Medicine
Methodology	Lectures, consultations, seminars, colloquiums

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to Pathological Physiology. Sickness and health. The disease etiopathogenesis. Death and the aging of cells.
I week exercises	Introduction to Laboratory Medicine
II week lectures	Pathophysiology of inflammation. Changes in the hearth inflammation and systemic reactions of the organism
II week exercises	Determination of laboratory analysis specific to the diagnosis of inflammation: sedimentation rate of red blood cells, C-reactive protein
III week lectures	Disorders of the metabolism of carbohydrates.Pathophysiology of diabetes mellitus. Hypoglycaemia.
III week exercises	Blood glucose measurement, interpretation of findings
IV week lectures	Disorders of protein metabolism. Malnutrition. Disorders of metabolism of vitamins.
IV week exercises	Measurement of total serum protein. The interpretation of the findings.
V week lectures	Lipoprotein serum disorders. Atherosclerosis. Obesity.
V week exercises	Measurement of serum concentrations of cholesterol and triglycerides, interpretation of findings
VI week lectures	Disorders of metabolism of body fluids and electrolytes. Shock.
VI week exercises	Interpreting laboratory analyzes typical of certain types of dehydration (isotonic, hypotonic, hypertonic) and hyperhydration
VII week lectures	Etiopathogenesis of functional disorders of the endocrine glands and neuroendocrine regulation. Function disorders of the pituitary gland and the thyroid gland
VII week exercises	Interpretation of laboratory analysis of typical disturbances of pituitary and thyroid glands: acromegaly, hyperprolactinemia, hyper and hypothyroidism
VIII week lectures	Function disorders of the adrenal and sex glands
VIII week exercises	Interpretation Lab. Analysis of typical disturbances of the adrenal glands (Cushing's syndrome, Addison's disease)
IX week lectures	Disorders of red and white blood cells.
IX week exercises	Interpretation of the lab. analysis typical for anemia and erythrocytosis. Interpretation of the laboratory analysis and microscopic preparations (differential white blood cell count) in different clinical conditions
X week lectures	Disorders of the hemostatic system functions. Thrombasthenias
X week exercises	Measuring the number of platelets. Determination of bleeding time
XI week lectures	The pathophysiology of heart failure. Hypertension
XI week exercises	Electrocardiogram, interpretation, basic elements. Changes in the electrocardiogram typical for certain disorders of cardiac function
XII week lectures	Disturbances on the nourishment of the heart muscle. Arrhythmias
XII week exercises	Biochemical changes in myocardial infarction: determination of serum concentrations of enzymes whose quantity in the blood increases in infarction,
XIII week lectures	Disorders of the respiratory system, disorders of ventilation, respiratory insufficiency
XIII week exercises	Spirometry: spirometry parameters calculation and interpretation of ventilation disorder obstructive and restrictive type
XIV week lectures	Pathophysiology of the gastrointestinal tract and liver. Ulcer disease. Differential diagnosis of hyperbilirubinemia
XIV week exercises	Determination of bilirubinaemia and bilirubinuria
XV week lectures	Malignant transformation and growth.
XV week exercises	Carcinogenesis- seminar

Student workload	weekly:4 credits x 40/30 = 5.3 hours Structure: 2 hours of lectures 2practical 1 hour seminar 0.3 hours for individual work, including consultations In the course of the semester Teaching and the final exam: (5.3hx16 = 84.8h) Preparation before the start of the semester (administration, enrollment, etc) 2hx5.3 = 10.6 Total work hours for the course: 4x30 = 120h Additional work 24.6h Structure: 84.8 + 10.6 + 24.6 = 120h
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 2 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	The student is required to attend classes and to prepare exercises
Consultations	According to the schedule
Literature	Leposavic, Pathological Physiology for students of Pharmacy, School of Pharmacy, University of Belgrade Manual of practical exercises and seminars from pathological physiology, Med. Faculty of Novi Sad, Test questions from pathological physiology, edi
Examination methods	- Two colloquiums 20 points - Attending lectures and exercises by 5 points (10 in total) - Final exam = 50 points - The passing grade is obtained if the cumulative set min 51 points The range of points and marks: 51-60 0ocjena E, D 61-70 score, score
Special remarks	Theoretical classes are held for all students together, practical classes in groups no larger than 15 students
Comment	No

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PATHOLOGICAL PHYSIOLOGY

Course:

PATHOLOGICAL PHYSIOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
28	Obavezan	5	5	3++2

Programs	PHARMACY
Prerequisites	none
Aims	Objectives of the course: The aim of the course is to acquaint students with the etiology factors and mechanisms that disturb the normal function of cells, resulting in the formation of functional and morphological changes and understanding the mechanisms of the development and course of the disease.
Learning outcomes	After attending the course and passing the exam, the student should: 1. Understands basic medical terminology; 2. Reproduces medically relevant facts adequately; 3. Understands the etiology and pathogenesis of basic metabolic and functional disorders of human organs and organ systems and is able to connect their clinical manifestations with the causes and mechanisms of their occurrence; 4. Understands the mechanisms of action of chemical agents and medicines; 5. Knows the pathobiological basis for the diagnostic strategy in case of pathological phenomena.
Lecturer / Teaching assistant	Name and surname of teachers and associates: Milica Martinović,PhD,full professor and teaching assistants engaged at the Faculty of Medicine of UoM
Methodology	Course content (teaching units, forms of individual student work, forms of knowledge assessment) shown according to working weeks in the academic calendar)

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Lecture: - Pathophysiology of inflammation, etiological agents. Pathogenesis of the local inflammatory process and systemic reaction of the organism. Biological etiological factors
I week exercises	Exercises: Determination of erythrocyte sedimentation rate, CRP, leukocytes, leukocyte formula, interpretation of clinical and laboratory inflammation prototypes
II week lectures	Lecture: Disorders of carbohydrate metabolism: hyperglycemia, hypoglycemia. Pathophysiology of diabetes mellitus; Disorders of protein metabolism. Nitrogen balance. Malnutrition. Hypoproteinemia.
II week exercises	Exercises: Determination of glycemia, glycosuria, interpretation of clinical and laboratory assigned prototypes DM type I and II, complications of diabetes, Determination of total serum proteins, interpretation of clinical and laboratory assigned prototypes of met. Protein disturbances
III week lectures	Lecture: Disorders of lipid metabolism: hyperlipoproteinemia, hypolipoproteinemia. Lipid deposition disorders, atherosclerosis. Obesity.
III week exercises	Exercises: Determination of LDL, VLDL, HDL cholesterol. Interpretation of clinical and laboratory given prototypes of hyperlipoproteinemia
IV week lectures	Disorders of water and electrolyte metabolism. Dehydration and hyperhydration. Disorders of body water and sodium metabolism. Pathophysiology of edema. SHOCK
IV week exercises	Exercises: Interpretation of clinical and laboratory assigned prototypes of fluctuations in serum electrolyte concentration and body water metabolism
V week lectures	Lecture:Endocrinopathies, Part I: disorders of hormone secretion, Por. in the target tissue. Disturbances in the regulation of hormonal systems. Pituitary function disorders. Thyroid gland function disorders.
V week exercises	Exercises: Endocrinopathies, Part I: Interpretation of clinical and laboratory assigned prototypes of pituitary, thyroid gland function disorders
VI week lectures	Lecture:Endocrinopathies, Part II: Disorders of adrenal gland function. Disorders of the gonadal disfunction .
VI week exercises	Exercises: Endocrinopathies, part II: Interpretation of clinical and laboratory assigned prototypes of adrenal and gonadal function disorders
VII week lectures	Lecture: Disorders of blood composition of hematopoietic organs: red blood cell, anemia, polycythemia and erythrocytosis
VII week exercises	Exercises: Determination of lab. values of hematocrit, hemoglobin, erythrocytes. Lab. recognition of different types of anemia. Interpretation of clinical and laboratory assigned prototypes of various types of anemia. COLLOQUIUM I
VIII week lectures	Lecture: Disorders of blood composition of hematopoetic organs: white blood cells, immunocytes, phagocytes. Leukemias; Pathophysiology of the spleen
VIII week exercises	Exercises: leukocytes, changes in the leukocyte formula in various pathophysiological disorders; Interpretation of clinical and laboratory assigned prototypes of various types of leukemia
IX week lectures	Lecture: Disorders of blood coagulation. Bleeding tendency, hemorrhagic syndromes. Blood hypercoagulability, disseminated intravascular coagulation syndrome
IX week exercises	Exercises: Laboratory determination of Ivy bleeding time, APTT, prothrombin time, Rumpelle-Leed test, platelet count; Interpretation of clinical and laboratory assigned prototypes of disorders of the function of the hemostasis system
X week lectures	Lecture: Pathophysiology of the cardiovascular system: Disorders of the myocardium. Phasic and tonic monitoring of myocardial work. Ischemic heart disease, heart failure
X week exercises	Exercises: Interpretation of ECG - position of the axis of the heart, pathophysiological aspects of electrocardiogram interpretation, Interpretation of clinical and given ECG prototypes of heart muscle function disorders
XI week lectures	Lecture: Pathophysiology of the cardiovascular system: Rhythm disorders. Arterial hypertension, myocardial infarction
XI week exercises	Exercises: Laboratory determination of troponin, CK-MB. Interpretation of clinical, biochemical and EKG established prototypes of heart muscle nutrition disorders. Arrhythmias
XII week lectures	Lecture: Pathophysiology of breathing. Alveolar ventilation disorders. Pathophysiology of asthma. Lieut. gas diffusion. Respiratory insufficiency
XII week exercises	Exercises: Spirometry, interpretation of findings of obstructive and restrictive ventilation disorders. Measurement of peak expiratory flow rate
XIII week lectures	Lecture: Pathophysiology of the digestive system: disorders of the pharynx and esophagus. Ulcer disease.
XIII week exercises	Exercises: Breath test for H. Pylori. Interpretation of given prototypes of disorders of digestive tract function. COLLOQUIUM II
XIV week lectures	Lecture: Pathophysiology of the hepatobiliary tract: Disorders of the metabolic function of the liver. Bilirubin metabolism disorders. Jaundice.
XIV week exercises	Exercises: Determination of bilirubinemia, bilirubinuria
XV week lectures	Lecture: Malignant transformation and growth. Carcinogenesis. Etiopathogenetic factors of malignant transformation of human cells. Tumor-host relationships.
XV week exercises	Exercises: Tumor markers, importance of determination, interpretation of results and positions in clinical and laboratory medicine

Student workload	Weekly 5 credits x 40/30 = 6.3 hours Structure: 2 hours of lectures 2 hours of exercises 2 hours of seminar work 0.3 hours of independent work, including consultation During the semester Lessons and final exam: (5.3x16 = 84.8h) Necessary preparations before the beginning of the semester (administration, registration, certification) 2x5.3=10.6 Total workload for the course 5x30=150h Additional work 24.6 hours Load structure: 84.8+10.6+24.6 = 140h
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 3 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	Obligations of students during classes: regular attendance of classes and exercises
Consultations	According to the schedule
Literature	1. Literature: 1. Leposavić G., Pathological physiology for pharmacy students, III amended and modified edition, Belgrade 2016. 2. Borota R., Lučić A, Manual of practical and seminar exercises in pathological physiology, University of Novi Sad, Faculty of Medicine, Novi Sad. in 2011
Examination methods	Forms of knowledge testing and assessment: - Two colloquiums of 20 points each - Attendance at lectures and exercises 5 points each (10 in total) - Final exam = 50 points - A passing grade is obtained if a minimum of 51 points is accumulated, Range of points and grades: 51-60 0 grade E, 61-70 grade D, 71-80 grade C, 81-90 grade B, 91-100 A
Special remarks	Specifics that need to be emphasized for the subject: Theoretical teaching takes place for all students together, practical teaching in groups of no more than 15 students
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BROMATOLOGY

Course:

BROMATOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
5956	Obavezan	5	6	3++3

Programs	PHARMACY
Prerequisites	None
Aims	Introduction to: - chemical composition of food and their potential to meet the nutritional and energy needs of people; - basic characteristics of macro- and micronutrients: energy value, chemical properties, basic roles in the organism, biological value; - types of food according to the role in the organism; - categories and specifics of food for special nutritional needs, as well as with food supplements; - nutrient interactions; - basic characteristics of food and drinking water contaminants, as well as food additives.
Learning outcomes	1. Know the basic characteristics of macro and micronutrients and their role in health and disease; 2. Understand the basic characteristics of the chemical composition of food; 3. Use the acquired knowledge in order to provide information on the proper selection of food and combinations of food to various population groups; 4. Use the acquired knowledge in order to provide the basic information on dietary products and supplements to patients.
Lecturer / Teaching assistant	Dejan Jančić, PhD; Sandra Jančić, spec. in Sanitary chemistry
Methodology	Lectures and laboratory work

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to food chemistry and nutrition; principal definitions; the role of food and nutrition knowledge in pharmacy education and practice
I week exercises	Introduction to basic principles of laboratory work in the food chemistry laboratory; safety precautions for laboratory work
II week lectures	Chemical composition of food, nutrients and non-nutritive food ingredients; energy value of food; principles of rational nutrition
II week exercises	Basic laboratory equipment in the food chemistry laboratory: analytical balance, dry oven, muffle furnace, polarimeter, refractometer, spectrophotometer, Kjeldahl protein determination apparatus. Determination of water content by drying and total and soluble dry matter of food.
III week lectures	Macronutrients; Proteins-chemical structure, amino acids. Biological value of food proteins, test methods
III week exercises	Basic principles of protein analysis in foods - quantification and biological value. Application of volumetric methods in protein content analysis in foods. Determination of proteins by Kjedahl.
IV week lectures	Carbohydrates-chemical structure and division, basic reactions; the role of carbohydrates in the body
IV week exercises	Application of spectrophotometric methods in the analysis of protein content in foods. Determination of connective tissue protein (collagen) content.
V week lectures	Lipids-chemical structure and division
V week exercises	Basic principles of carbohydrate analysis in foods. Application of volumetric methods in the analysis of carbohydrate content in foods. Determination of direct-reducing sugars and total sugars after inversion by the Loof-Schoorl method
VI week lectures	Basic reactions of lipids, the role of lipids in the body
VI week exercises	Application of volumetric and polarimetric methods in the analysis of individual carbohydrate content in foods. Determination of glucose in the presence of fructose and polarimetric determination of sucrose.
VII week lectures	Vitamins, division, utilization; Basic nutritional characteristics of water-soluble vitamins
VII week exercises	Basic principles of lipid analysis in foods. Gravimetric determination of total lipid content by the Soxhlet method and quality control (deterioration).
VIII week lectures	Basic nutritional characteristics of liposoluble vitamins; vitamin toxicity
VIII week exercises	Application of volumetric methods in food lipid analysis. Determination of iodine and saponification number.
IX week lectures	Basic nutritional characteristics of minerals; bioavailability of minerals
IX week exercises	Basic principles of vitamin analysis in foods and sample preparation. Volumetric determination of vitamin C content.
X week lectures	Foodstuffs, disivison; principles of proper nutrition; the food pyramid; foodstuffs as sources of macro and micronutrients
X week exercises	Application of spectrophotometric and HPLC methods for analysis of vitamin content in food. Determination of B vitamins using liquid chromatography.
XI week lectures	Foods for special nutritional purposes and dietary supplements - basic characteristics. Water as food.
XI week exercises	Basic principles of analysis of mineral content in foods. Determination of total mineral content gravimetrically.
XII week lectures	Effects of heat treatment on nutrients
XII week exercises	Basic principles of drinking water analysis. Determination of pH value, electrical conductivity, turbidity and anions (nitrates, nitrites, sulfates, chlorides).
XIII week lectures	Food additives
XIII week exercises	Quantitative analysis of food additives - analysis of preservatives and sweeteners using liquid chromatography. Determination of preservatives and sweeteners by HPLC technique (benzoic and sorbic acid, acesulfame K, saccharin, aspartame).
XIV week lectures	Contaminants and residues in food
XIV week exercises	Residues and contaminants in food and drinking water. Analysis of toxic metals and pesticide residues by AAS and gas chromatography.
XV week lectures	Preparing for the exam
XV week exercises	Preparing for the exam

Student workload	On weekly basis: 6 credits x 40/30 = 8 hours and 20 min Structure: 3 hours of lectures 3 hours laboratory work 2 hours and 20 min of individual work
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	1. Pre-examination obligations: - regular attendance at classes and laboratory exercises; - two tests; - final exam in practical classes 2. Final exam
Consultations	Before and after lectures
Literature	1. Modeiros D. M., Wildam R. E. C. 2019. Advanced Human Nutriton, fourth edition. Burlington, MA: Jones & Barlett Learning, USA 2. Belitz H. D., Grosch W. 2004. Food Chemistry. Springer, Berlin, 3rd edition 3. Coultate T. P. 1995. Food: The chemistry of its components. Royal Society of Chemistry, Herts 4. Stanimirović S. 1979. Bromatologija - opšti deo. Farmaceutski fakultet Beograd, Zavod za bromatologiju, Beograd 5. Radna sveska iz bromatologije. Izdanje Farmaceutskog fakulteta u Beogradu 6. Grujić R., Miletić I. 2006. Nauka o ishrani čovjeka – kniga prva. Tehnološki fakultet Univerziteta u Banjoj Luci. 7. Grujić R., Miletić I., Stanković I. 2007. Nauka o ishrani čovjeka - knjiga druga. Tehnološki fakultet Univerziteta u Banjaluci 8. Mirić M., Šobajić S. 2002. Zdravstvena ispravnost namirnica. Zavod za izdavanje udžbenika i nastavna sredstva, Beograd
Examination methods	Forms of knowledge testing and assessment: - class attendance (0-5 points) - activity during the lecture - 2 tests to test knowledge (0-30 points), - laboratory exercises (0-5 points), - final exam in laboratory exercises: (0-10 points), - final exam: (0-50 points). Mark: A B C D E F Poens: 90-100 80-89 70-79 60-69 50-59 < 50 A passing grade is obtained if the student cumulatively collects at least 50 points. - final exam in practical classes: (0-10 points), - final exam: (0-50 points).
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOGNOSY II

Course:

PHARMACOGNOSY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6766	Obavezan	5	6	3++3

Programs	PHARMACY
Prerequisites	Pharmacognosy I.
Aims	Acquiring knowledge about the most important natural medicinal raw materials (drugs) of importance for medicine and pharmacy: definition and characteristics; identification methods; ingredients; quality; production; action and application.
Learning outcomes	After the lectures and exercises, students will acquire the knowledge and skills to: 1. Recognize the most important medicinal plant raw materials of importance for medicine and pharmacy; 2. Recognize the chemical composition, pharmacological area of action, use in prevention and treatment; 3. Recognize herbal drugs, their action and application; 4. Recognize the methods of drug identification.
Lecturer / Teaching assistant	Dr sc. pharm. Tijana Mićović
Methodology	Interactive lectures, practical classes, seminars, colloquium, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Phytotherapy, Natural medicinal raw materials - drugs; Definition, division, application of drugs.
I week exercises	Anatomy of the basic organs of the plant organism.
II week lectures	Drug production. Quality of drugs. Pharmacopoeial drug monographs.
II week exercises	Macroscopic, microscopic and microchemical analysis of drugs.
III week lectures	Extractive preparations and drug extracts. Pharmacopeial monographs.
III week exercises	Morphological and anatomical characteristics of underground organs, root, rhizome, tubers, bulbs.
IV week lectures	Alkaloid drugs used in the form of extracts.
IV week exercises	Morphological and anatomical characteristics of bark as an important organ, pear, juniper, pomegranate, oak.
V week lectures	Drugs containing glucosinolates and cyanogenic heterosides, betalains, lectins.
V week exercises	Morphological and anatomical characteristics of leaves, mint, senna, mallow, ear, lemon balm, birch, eucalyptus, rosemary.
VI week lectures	Drugs with simple phenols and phenolic acids, coumarins and lignans.
VI week exercises	Above-ground parts of plants-herbs, St. Johns wort, Club moss, Fleabane, Yarrow.
VII week lectures	Drugs with flavonoids, isoflavones, chalcones, anthocyanins, tannins.
VII week exercises	Leaves of alkaloid drugs, belladonna, hyosiamus.
VIII week lectures	Drugs with benzoquinones, naphthoquinones and anthranoids.
VIII week exercises	Composition of leaves of aromatic drugs, sage, mint, thyme.
IX week lectures	Drugs with iridoids.
IX week exercises	Morphology and anatomical structure of fruits and seeds.
X week lectures	Drugs with sesquiterpenes, diterpenes, triterpenes.
X week exercises	Macroscopic analysis of drugs.
XI week lectures	Drugs with triterpene saponosides.
XI week exercises	Processing counterfeit drugs.
XII week lectures	Drugs with steroidal saponosides and phytosterols. Colloquium from the theoretical part of the material.
XII week exercises	Macroscopic observation of drugs.
XIII week lectures	Aromatic drugs.
XIII week exercises	Analysis of tea mixtures taken from pharmacies.
XIV week lectures	Fatty oils and waxes, Carbohydrates, mucus and mucus drugs. Colloquium from the practical part of the material.
XIV week exercises	Observation of permanent preparations.
XV week lectures	Final exam.
XV week exercises	Make up from the final exam.

Student workload	In the semester Teaching and final exam (8 hours and 20 minutes) x 16 = 133 hours and 20 minutes. Necessary preparations before the beginning of the semester (administration, registration, certification) 2 x 8 hours and 20 minutes = 16 hours and 40 minutes. Total load on the subject: 6 x 30 = 180 hours. Additional work: 31 hours. Structure workload: 133 hours and 20 minutes (teaching) + 16 hours and 40 minutes (preparation) + 31 hours (additional work) = 180 hours
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises.
Consultations	Consultations take place by agreement with students.
Literature	1. Kovačević N. Basics of pharmacognosy. Serbian school book, Belgrade, 2002. 2. Gorunović M., Lukić P.: Pharmacognosy. Faculty of Pharmacy, Belgrade, 2001. 3. Bruneton, J. Pharmacognosy, Phytochemistry, Medicinal Plants, 2nd ed. Lavoisier Publishing, Paris, 1999. 4. Hänsel R, Sticher O, Steinegger E. Pharmacognosie-Phytopharmazie. Berlin, Heidelberg: Springer-Verlag, 1999. 5. Tucakov, J: Healing with herbs, Rad, Belgrade, 1984. 5. Petrović S, Maksimović Z, Kundaković T. Analysis of herbal drug ingredients. Faculty of Pharmacy, Belgrade, 2009. 6. Kundaković T, Drobac M, Petrović S, Maksimović Z, Marchetić M. Macroscopic and microscopic analysis of herbal drugs. Faculty of Pharmacy, Belgrade, 2017. 7. Petrović S, Maksimović Z, Kundaković T. Chemical analysis of herbal drugs and ingredients. Faculty of Pharmacy, Belgrade, 2013. 8. Monographs according to European pharmacopoeias
Examination methods	Activities during lectures, assessment of practical classes, presentations, seminar papers, colloquium, final exam. Pre-examination requirements: 50 points; Attendance at lectures (0-5) points; Exercise activity and exercise preparation (0-15); Colloquium from the theoretical part of the material (0-10 points); Colloquium from the practical part of the material (0-20 points). Final exam: 0-50 points A passed exam means a cumulative score of 50 points and more.
Special remarks	Theoretical teaching takes place for all students together, practical teaching in groups of no more than 15 students.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOLOGY I

Course:

PHARMACOLOGY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6770	Obavezan	5	6	3++3

Programs	PHARMACY
Prerequisites	Physiology II.
Aims	Acquisition of basic knowledge about drugs, understanding effects of drugs on the systems, and their movements throughout the body, manner, mechanism and site of action, side effects, interactions and intoxications.
Learning outcomes	1. understand the basics of pharmacology and explain the application of drugs in accordance with the modern treatment guidelines; 2. understand the pharmacokinetics and pharmacodynamics of the main groups of drugs; 3. identify the expected effects of drugs as well as their adverse reactions and interactions; 4. understand the interaction mechanisms of individual drugs and explain the interactions, taking into account the underlying mechanisms; 5. find relevant information regarding rare drugs; 6. explain the basics of clinical trials of drugs, as well as regulations related to this field; 7. define certain groups of drugs and their specific characteristics; 8. explain the application of certain drugs, in line with the modern treatment guidelines, in the treatment of certain diseases, based on evidence, and identify the drug groups used to treat certain types of diseases.
Lecturer / Teaching assistant	Majda Šahman -Zaimović, MD, PhD, teacher; Džana Lukač, dr pharm. assistant
Methodology	Interactive lectures, practical classes, colloquia.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	History of pharmacology, division on disciplines. The drug and poison. Preclinical and clinical investigation of drugs. Pharmacovigilance.
I week exercises	The definition of drug. The criteria for the division of medicines. Examples.
II week lectures	Methods of application of drugs. The dosage of the drugs. Dose. The therapeutic index of the drug and the therapeutic spectrum.
II week exercises	Basic terms in pharmacology. Advantages and limitations of different methods of administration of drugs. Examples.
III week lectures	The movement of the drug through the organism. The passage of drugs through biomembranes. Absorption and distribution of drugs.
III week exercises	The pharmacokinetics. Absorption and distribution of drugs. Bioavailability. The volume of distribution. Examples.
IV week lectures	The metabolism of the drugs. Induction and inhibition of the enzyme. Factors that alter the metabolism of drugs.Excretion of drugs.
IV week exercises	Metabolism and excretion of drugs. The most important inducers and inhibitors in pharmaceutical practice. Clinical significance and examples.
V week lectures	Modes of action of drugs. Places of the effects of drugs. The mechanisms of action of drugs. The receptors. G-protein.
V week exercises	The mechanisms of action of drugs. Practical examples.
VI week lectures	Interaction of drugs. Synergism and antagonism. Undesirable effects of medicines.
VI week exercises	The most common examples and opportunities for prevention of drug interactions in pharmaceutical practice. Pharmacovigilance.
VII week lectures	Use of drugs in special conditions (children, the elderly, pathological conditions, pregnant women, breast-feeding).
VII week exercises	Optimal selection and dosage of drugs under special conditions (children, the elderly, pathological conditions, pregnant women, breast-feeding). Examples.
VIII week lectures	Tolerance to drugs. Addictions.
VIII week exercises	Tolerance to drugs - mechanisms of formation and consequences. The most common examples of addiction.
IX week lectures	Basic principles of treatment of poisoning. Poisons and Antidotes.
IX week exercises	The most frequent acute poisoning in clinical practice, with special reference to the poisoning with pharmacologically active substances. Examples.
X week lectures	The principles of action of antimicrobial drugs. Optimal application of antibiotics. Classification.
X week exercises	Prescription. Content of the prescription. The methods of prescribing of drugs. The role and importance of pharmacists in the correct preparation and dispensing of medicines.
XI week lectures	Inhibitors of cell wall synthesis.
XI week exercises	Optimal selection of antimicrobial drugs that inhibit cell wall synthesis (depending on the mechanism of action, given indications, dosage forms, pharmacokinetic properties, etc.). Examples.
XII week lectures	Protein synthesis inhibitors.
XII week exercises	Optimal selection of antimicrobial drugs that inhibit protein synthesis (depending on the mechanism of action, given the indication, form of the drug, the pharmacokinetic characteristics etc.). Examples.
XIII week lectures	Antibacterial drugs that affect DNA.
XIII week exercises	Optimal selection of antimicrobial drugs that affect DNA (depending on the mechanism of action, given the indication, form of the drug, the pharmacokinetic characteristics etc.). Examples.
XIV week lectures	Antifungals. Anti-parasitic drugs. Antivirals. Immunomodulators.
XIV week exercises	Antimycotics, antiparasitic drugs, antivirals, immunomodulators - optimal choice depending on the mechanism of action, indication, form of the drug, the pharmacokinetic characteristics, etc. Examples.
XV week lectures	Antituberculosis drugs. Cytostatics.
XV week exercises	Pre-examination exercise.

Student workload	Per week: 5 credits x 40/30 = 7 hours Structure: 3 lectures 2practical 2 hours of independent work. In the course of the semester: Teaching and the final exam (7 hours x 16 = 112h). Necessary preparation (before semester enrollment, etc ...) 2hr x 7 = 14 hours Total work hours for course: 5x30 = 150 hours Additional work 24 hours Work hours structure 14 + 112 + 24 = 150 hours
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	The presence and active participation in the theoretical and practical training, as well as all forms of assessment is required.
Consultations	The course lecturer and teaching assistants held consultations with students once a week in the period which is defined at the beginning of academic year.
Literature	1.Varagić V., Milošević M. Farmakologija, XXII izdanje. Elit medica, Beograd 2012. 2. Rang HP, Dale MM, Ritter JM, Moore PK. Farmakologija, osmo izdanje. Churchill Livingstone, 2015. 3. Duborija-Kovačević N i sar. Oblici ljekova sa recepturom, prvo izdanje
Examination methods	The forms of knowledge testing and grading: Attendance at lectures (0-5 points) The presence and activity of the exercises: (0-5 points) Colloquium I and II: (0-20 + 0-20 points) Final exam (0-50 points) Final exam is written. Passing grade gets the 50 points
Special remarks	None.
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL CHEMISTRY II

Course:

PHARMACEUTICAL CHEMISTRY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6767	Obavezan	5	7	3++3

Programs	PHARMACY
Prerequisites	Pharmaceutical chemistry I
Aims	The student is expected to acquire basic knowledge in medical chemistry and chemistry of drugs of certain pharmacotherapeutic groups. The acquired knowledge in these areas is important for mastering the teaching contents of medical, pharmaceutical-technological grouping of subjects and pharmaceutical practice.
Learning outcomes	1. Assess the basic physical and chemical properties of the pharmacologically active molecules and their impact on the behavior of drugs in the body; 2. Apply the knowledge of functional groups in the evaluation of the relation between the structure and the activity of drugs; 3. Establish the basic mechanisms of drug action in the context of the studied groups; 4. Assess chemical interactions of drugs; 5. Identify the most important drug-target interactions; 6. Estimate the chemical aspects of the drug transformation in vitro and in vivo conditions.
Lecturer / Teaching assistant	PharmD, PhD, Nemanja Turković, PharmD, Sehija Dizdarević, PharmD, Jadranka Orović
Methodology	teaching, practical work, colloquia

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Steroid hormones: nomenclature, stereochemistry and stereochemical modifications Estrogen hormones (chemical structure, metabolism, relationship between structure and activity, semi-synthetic preparations) and anti-estrogens
I week exercises	Steroids in therapy
II week lectures	Steroid hormones: Androgenic hormones, anabolics and antiandrogens; Progestogenic hormones and hormonal contraception; Mineralocorticoids (aldosterone, deoxycorticosterone, fludrocortisone)
II week exercises	Steroids in therapy
III week lectures	Steroid hormones and thyroid hormones; Glucocorticoids ((chemical structure, metabolism, relationship between structure and activity); Anti-inflammatory steroids (structural modification of cortisol in order to increase the anti-inflammatory effect); Thyroid hormones (thyroxine) and thyrostatics
III week exercises	Steroids in therapy
IV week lectures	Vitamins: Water-soluble vitamins - B vitamins and vitamin C (chemical properties, biological role, coenzymes, vitamin stability and antivitamins); Liposoluble vitamins: vitamins A, D, E and K (chemical properties, nomenclature, activation and biological role;
IV week exercises	Selected syntheses
V week lectures	Beta-lactam antibiotics: Penicillins, natural and semi-synthetic; Chemistry, properties, stability, distribution and microbiological activity; Beta lactamase inhibitors and carbapenems;
V week exercises	Beta-lactam antibiotics: Penicillins, natural and semi-synthetic; Beta lactamase inhibitors and carbapenems;
VI week lectures	Cephalosporins, natural and semi-synthetic: Chemistry, properties, stability, partitioning and microbiological activity. Chemical aspects of the mechanism of action and resistance.
VI week exercises	Cephalosporins, natural and semi-synthetic
VII week lectures	Tetracyclines and aminoglycoside antibiotics - natural and semi-synthetic: Chemistry, properties, stability, distribution and microbiological activity; Chemical aspects of the mechanism of action and resistance;
VII week exercises	Tetracyclines and aminoglycoside antibiotics
VIII week lectures	Macrolides, lincosamides and polypeptide antibiotics - natural and semi-synthetic: Chemistry, properties, stability, distribution and microbiological activity. Chemical aspects of the mechanism of action and resistance.
VIII week exercises	Selected syntheses
IX week lectures	Local anti-infectives: Definitions, division, chemical aspects of the mechanism of action, chemical properties, division by functional groups; antiseptics and disinfectants: alcohols, phenols, aldehydes, carboxylic acids, branched compounds of chlorine, mercury, triphenylmethane dyes, acridines, heterocyclic derivatives of 5-nitrofuran, 8-oxyquinoline and others;
IX week exercises	Selected syntheses
X week lectures	Antimycotics, polyene macrolides: Chemical properties, stability, chemical aspects of the mechanism of action; Synthetic antifungals: azoles - derivatives of imidazole and triazole (metronidazole, ketoconazole, fluconazole) of various structures; ciclopiroxolamine, griseofulfin and others; Antituberculotic agents, division, properties, metabolism, ansamycins;
X week exercises	Selected syntheses
XI week lectures	Antivirotics: Division, chemical aspects of the mechanism of action, metabolic activation, prodrug substance;
XI week exercises	Selected syntheses
XII week lectures	Antivirals and antineoplastics: Antineoplastics, alkylating agents, antimetabolites, antibiotics, taxanes, antihormones and others; Chemical aspects of the mechanism of action, chemical properties, metabolism, division;
XII week exercises	Selected syntheses
XIII week lectures	Sulfonamides: Chemical aspects of the mechanism of action, chemical properties, metabolism, division; Quinolones, ciprofloxacin, chemical properties, chemical aspects of the mechanism of action, uroantiseptics;
XIII week exercises	Sulfonamides, uroantiseptics
XIV week lectures	Insulin, oral antidiabetics, sulfonylurea derivatives, biguanides, glinides, glitazones, sugar substitutes
XIV week exercises	IR spectrophotometry
XV week lectures	Review of material and preparation for the exam
XV week exercises	NMR spectrophotometry

Student workload	3 hours lectures, 3 hours practical work and 3,33 hours student independent work including consulting. Week: 9,33 hours. Semester: 149,33 hours.
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance in lectures and practical work
Consultations
Literature	1. Wiliams DA, Lemke TL. Foye‘s Principles of Medicinal Chemistry. 7th rev. ed. Philadelphia: Lippincott Williams & Wilkins; 2013. 2. Beale JM, Block JH. Wilson and Gisvolds Textbook of Organic Medicinal and Pharmaceutical Chemistry. 12th rev. ed. Philadelphia: Lippincott Williams & Wilkins; 2011. 3. Vladimirov S, Živanov-Stakić D. Farmaceutska hemija, II deo. Beograd: Farmaceutski fakultet; 2006. 4. European Pharmacopoeia. 11th ed. Strasbourg: Council of Europe; 2023.
Examination methods	Attendance n lectures and practical work: 0-10 points Activity in practical work: 0 - 15 points Colloqia: 0-25 points Final exam: (0-50 points) (student can take a colloqium for a part of course material)
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOLOGY II

Course:

PHARMACOLOGY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6772	Obavezan	6	6	3++3

Programs	PHARMACY
Prerequisites	No subject conditionality.
Aims	Mastery of specific knowledge of drugs that are studied within the subject (mechanisms of action of the drug, the fate of the drug in the human body, pharmacological effects, the possibilities and limitations of the therapeutic use, side effects, interactions).
Learning outcomes	1. Define and explain the mechanisms of action of pharmacotherapeutic groups of drugs which are studied within the course; 2. Describe the most important pharmacokinetic properties of certain groups of drugs (absorption, distribution, metabolism and excretion) and compare the pharmacokinetic specificities of some drugs within the groups, which are of importance for their application; 3. Find the link between the indications and contraindications for the use of the drug, and the drug’s pharmacological effects; 4. Recognise the adverse effects of drugs in everyday pharmaceutical practice; 5. Predict and identify clinically significant drug interactions and act in order to avoid them; 6. Explain to the patient how to properly choose OTC preparations and how to apply certain drugs; 7. Analyse the content of the medical prescription and identify any irregularities (recipe structure, selection of preparation, dosage regimen, etc.).
Lecturer / Teaching assistant	Majda Šahman-Zaimović,MD,PhD, teacher Ljudmila Radivojević,dr pharm., assistant
Methodology	Interactive lectures, practice, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Pharmacology of the vegetative nervous system.
I week exercises	Pharmacology of the vegetative nervous system-chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
II week lectures	Drugs that modulate cholinergic transmission.
II week exercises	Drugs that modulate cholinergic transmission - selected examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
III week lectures	Drugs that modulate adrenergic transmission.
III week exercises	Drugs that modulate adrenergic transmission - selected examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
IV week lectures	Pharmacology of the central nervous system I.
IV week exercises	Drugs that act on the central nervous system I - chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
V week lectures	Pharmacology of the central nervous system II.
V week exercises	Drugs that act on the central nervous system II - chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
VI week lectures	Pharmacology of the central nervous system III.
VI week exercises	Drugs that act on the central nervous system III - chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
VII week lectures	Pharmacology of the cardiovascular system I.
VII week exercises	Drugs acting on the cardiovascular system I-chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
VIII week lectures	Pharmacology of the cardiovascular system II.
VIII week exercises	Drugs acting on the cardiovascular system II-chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
IX week lectures	Pharmacology of the cardiovascular system III.
IX week exercises	Drugs acting on the cardiovascular system III-chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
X week lectures	Pharmacology of blood.
X week exercises	Drugs that act on blood - chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
XI week lectures	Pharmacology of the endocrine system I.
XI week exercises	Drugs that act on the endocrine system I- chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
XII week lectures	Pharmacology of the endocrine system II.
XII week exercises	Drugs that act on the endocrine system II- chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
XIII week lectures	Pharmacology of the endocrine system III.
XIII week exercises	Drugs that act on the endocrine system III- chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
XIV week lectures	Pharmacology of the respiratory tract.
XIV week exercises	Drugs that act on the respiratory tract - chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).
XV week lectures	Pharmacology of the digestive tract.
XV week exercises	drugs that act on the digestive tract - chosen examples with which pharmacists usually encounter in everyday practice (indications, contraindications, side effects, interactions, optimal way of prescribing and administration).

Student workload	3 hours of lectures and 3 hours of exercises per week
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	The presence on theoretical and practical courses, as well as all forms of assessment is required.
Consultations	The course lecturer and teaching assistants held consultations with students once a week in the period which is defined at the beginning of academic year.
Literature	1.Varagić V., Milošević M. Farmakologija. Elit medica, Beograd 2018. 2. Rang HP, Dale MM, Ritter JM, Moore PK. Farmakologija, osmo izdanje. Churchill Livingstone, 2015. 3.Duborija-Kovačević N i sar. Oblici ljekova sa recepturom. PRiSMA korporativne komunikacije, Podgorica, 2015. 4. Register of medicines in Montenegro 2017. Agency for medicines and medical devices, Podgorica 2018.
Examination methods	Lecture Attendance: 0-5 points. Colloquium I: 0-20 points. Colloquium II: 0-20 points. Preparation and presentation of the seminar: 0-5 points; Final exam (0-50 points) Final exam is written. Minimum Cumulative Grade Point is 50 points and more.
Special remarks	No
Comment	No.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / MEDICAL BIOCHEMISTRY

Course:

MEDICAL BIOCHEMISTRY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6774	Obavezan	6	6	3++3

Programs	PHARMACY
Prerequisites	No prerequsites
Aims	To make students familiar with mechanisms related to homeostasis of biochemical parameters and with homeostasis disorders, to be able to do biochemical research of organ function and to be able to explain the influence of drugs on the biochemical analysis results.
Learning outcomes	1. Understand the role of biochemical laboratory in the diagnosis, monitoring and treatment of disease; 2. Know the types of the biological materials used in biochemical laboratories (in healthy subjects and in various pathological and physiological conditions), the manner of their collection, processing and storage; 3. Based on the acquired knowledge of the theoretical principles underlying the method, select a proper method for a given parameter, as well as factors influencing such choice; 4. Select the appropriate analyser and be able to use it; 5. Understand the importance of determining the biochemical parameters and interpret the changes in the content of the biological material in various pathological and physiological conditions; 6. Assess the impact of drugs on specific biochemical parameters, use professional literature, identify and solve problems.
Lecturer / Teaching assistant	Snežana Pantović, Associate Professor Aleksandra Klisić, Assistant Professor
Methodology	Lectures, exercises, consultations, colloquiums

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to Medical Biochemistry. The role of biochemical laboratory. Kinds of biochemical materials. Influence of physiological factors.
I week exercises	/
II week lectures	Carbohydrates (Digestion and absorption. Role of liver and muscle in carbohydrate metabolism. Integration of carbohydrate metabolism with lipids and proteins metabolism. Influence of hormone on carbohydrate metabolism. Regulation of blood glucose concent
II week exercises	Introductory lecture (Biological materials: kinds and ways of taking. Ways of calculating concentrationof biochemical parameters. Calculations based on spectrophotometric and another measurements for determination biochemical parameters.Introduction with
III week lectures	Proteins (Digestion and absorption. Review of protein metabolism. Plasma proteins. Proteins in urine.)
III week exercises	Glucose: Quantitative determination by glucose-oxidase or hexokinase method
IV week lectures	Lipids (Normal lipids metabolism. Digestion and absorption. Triglycerides. Cholesterol. Metabolism of lipids in liver and in adipose tissue). Lipids (Lipoproteins - structure and metabolism. Atherosclerosis and lipoprotein metabolism. Disorders of lipo
IV week exercises	Proteins: Determination of total proteins and albumin levels. Electrophoresis. Infection: Determination of fibrinogen and CRP levels.
V week lectures	Water (Function and water metabolism. Disorders in metabolism. Disorders of body fluid osmolality). Electrolytes (Sodium, Potassium, Chloride. Intake and output. Regulation. Disorders of electrolytes metabolism)
V week exercises	Lipids: Determination of total cholesterol, triglycerides and HDL levels.
VI week lectures	Acid-base regulation (Origin base in body. Storage constant pH in body fluids. Disorders of acid base balance in blood)
VI week exercises	Enzymology - Determination of amylase activity.
VII week lectures	Enzymes (Entering the enzyme into the blood. Elimination of blood enzymes. Specificity of enzymes for individual organs. The activity of enzymes in diseases of various organs: AST, ALT, ALP, LDH, CK, amylase, GGT)
VII week exercises	Enzymology - Determination of AST, ALT and CK activity.
VIII week lectures	Colloquium 1
VIII week exercises	Enzymology - Determination of LDH, GGT and ALP activity.
IX week lectures	Colloquium-I Corrective Calcium, inorganic phosphorus and magnesium (Metabolism. Regulation of metabolism. Disorders of Ca, P and Mg concentration on blood)
IX week exercises	Electrolytes - Determination of sodium, potassium, calcium, magnesium and phosphorus concentrations.
X week lectures	Iron (Metabolism and regulation. Disorders in metabolism of iron. Parameters for determination iron status). Haemoglobin
X week exercises	Non-protein nitrogen substances: Determination of urea, creatinine and uric acid concentration.
XI week lectures	Kidney and non-protein nitrogenous compounds. Excretorial, regulatorial and endocrinal function of kidney. Urine analysis. Urine sediment. Urea. Creatine and creatinine. Uric acid.
XI week exercises	Bilirubin - Determination of total and direct bilirubin concentration.
XII week lectures	Colloquium 2
XII week exercises	Urine: Chemical determination. Quantitative determination of urine proteine
XIII week lectures	Liver (Determination of liver function. Bile acids. Determination of synthetic and metabolic liver function. Ammonia) Colloquium 2 - corrective
XIII week exercises	Urine: Microscopic study of urine sediment
XIV week lectures	Gastrointestinal tract (Function of stomach. Exocrine function of pancreas. Determination of function of digestion and absorption. Influence of drugs on results of biochemical parameters. Analytical influence. Pharmacological effecst. Colloquium-II Corec
XIV week exercises	Visit to laboratory in Clinical Centre of Montenegro
XV week lectures	Hormones - repetition.
XV week exercises	Final consultations.

Student workload	Weekly: 7 credits x 40/30 = 9 hours and 20 min. Structure: 3 hours lectures, 3 hours exercise, 3 hours for individual work including consultations.
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 2 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	Students are requested to attend lectures and exercises, to prepare practical work and to take colloquiums.
Consultations	According to the schedule
Literature	Spasic S., Jelic-Ivanovic Z., Spasojevic-Kalimanovska V.: Medicinska biohemija, Beograd 2003; Majkic-Singh N. Medicinska biohemija, Beograd 2006; Pantović S., Dožić I. Priručnik za laboratorijsku dijagnostiku, Podgorica, 2017.
Examination methods	Attending lectures 4 points; attending and activity at exercises 12 points; 2 colloquiums 2 x 10 (20 in total); practical part of final exam 14 points; final exam 50 points. The passing grade is obtained if the cumulative set min 50 points.
Special remarks	Theotical classes are held for all students together, practical classes in groups up to 12 students
Comment	Additional information about the course are provided by the lecturer or head of the study programme.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL CHEMISTRY III

Course:

PHARMACEUTICAL CHEMISTRY III/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6771	Obavezan	6	9	4++3

Programs	PHARMACY
Prerequisites	Pharmaceutical chemistry I; Pharmaceutical chemistry II
Aims	Course aims are providing students with: - Knowledge about chemical structures of drugs affecting CNS and cardiovascular system; - A comprehensive understanding of the underlying principles of drug action; - Identification of fundamental pharmacophores for drugs of selected pharmacotherapy groups; - Structure-activity relationships in relation to drug-target interaction; - Physicochemical properties of drug molecules in relation to drug ADME; - Chemical pathways of drug metabolism.
Learning outcomes	Having successfully completed this module student will be able to: • Answer rationally the “why” and “how” questions related to drug action; • Relate the structure and physical properties of drugs to their pharmacological activity; • Demonstrate an understanding of concepts such as drug metabolism, bioavailability and pharmacokinetics and the role of medicinal chemistry in improving these parameters; • Describe the current challenges and opportunities in medicinal chemistry in light of contemporary developments in the field of drug discovery; Think critically and solve problems related chemistry of drugs; • The gained knowledge is the basis for the following courses: pharmacology, drug metabolism, pharmaceutical technology and pharmaceutical analysis.
Lecturer / Teaching assistant	PharmD, PhD, Nemanja Turković, PharmD, Sehija Dizdarević, PharmD, Jadranka Orović
Methodology	Lectures, exercises, work in a small group, consultations, presentation in front of a group, method of practical student activities

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Analgesics. Opioid receptors, morphine: mechanism of action, chemical properties, stability, metabolism, adverse effects. Endogenous opioid peptides, structure-activity relationships of opioid agonists and antagonists, morphine-like drugs. Synthetic opioid series (methadone, fentanyl, meperidine, tramadol...). Opioid antidiarrheals.
I week exercises	Analyses of physical and chemical properties of chemical compouds; the way of analyses; The reactivity of functional groups; Felling’s and Tollens’s tests; Distinction between citric and tartaric acid, reactions of selected amines; Parris reaction, methylxanthines.
II week lectures	Nonsteroidal anti-inflammatory drugs (NSAID), cyclooxygenase (COX-1, COX-2) activities, and adverse effects. General structure-activity relationships, physicochemical properties of synthetic drugs. Classification: derivatives of aryl alkanoic acid, aryl- and heteroarylpropionic acids, oxicams, selective COX-2 inhibitors. Antirheumatic drugs, drugs for the treatment of gout. Analgoantipyretics.
II week exercises	Identification of inorganics anions and cations.
III week lectures	General anesthetics, historical aspect (ether, chloroform). Clinically useful inhalation agents (fluorinated hydrocarbons, ethers), hepatotoxicity. Clinically useful intravenous general anesthetic agents (propofol, ketamine, etomidate, ultrashort-acting barbiturates). Local anesthetics, toxicity, side effects, mechanism of action, structure-action relationship. The most important local anesthetics (benzocaine, bupivacaine, chlorprocaine, lidocaine...).
III week exercises	Identification of inorganic compounds by reactions of cations and anions.
IV week lectures	Drugs affecting cholinergic neurotransmission. Cholinergic neurotransmission, biosynthesis of acetylcholine, storage and release, chemistry, metabolism, structure-activity relationships. Cholinergic receptors (muscarinic and nicotinic receptors), muscarinic agonists, reversible acetylcholinesterase inhibitors, Alzheimers disease therapy.
IV week exercises	Pharmaceutical purity, the origin of impurities, in vitro stability, photochemical degradation, limit tests, methods used to test the purity of pharmaceutical substances.
V week lectures	Irreversible inhibitors of acetylcholinesterase, muscarinic antagonists, structure-activity relationships. Antiparkinsonian drugs: anticholinergics, L-DOPA. Nicotinic antagonists-neuromuscular blocking drugs (depolarizing and no depolarizing neuromuscular blockers, steroid structure drugs).
V week exercises	Impurities, examples from the pharmacopoeia, analysis of the instability of pharmaceutical substances, workshop for students - a sample of the instability of substances, the formation of potential degradation products and related compounds.
VI week lectures	Antidepressants: tricyclic antidepressants, selective reuptake inhibitors (noradrenaline, 5-HT, noradrenaline and serotonin, dopamine and noradrenaline). Monoamine oxidase inhibitors (nonselective, reversible MAO-A inhibitors). Anxiolytic drugs: GABAA receptors, benzodiazepines, structure-activity relationship. Non-benzodiazepine agonists acting on benzodiazepine receptors, other anxiolytics. Non-benzodiazepine sedative-hypnotics.
VI week exercises	Limit tests, control of personal errors, non-specific impurities: clarity and degree of opalescence of liquid, degree of coloring of liquid, insoluble matter, soluble matter, loss on drying, volatile matter and residual solvents, non-volatile matter, residue after annealing, sulfate residue.
VII week lectures	Antisizure drugs, mechanism of action: hydantoins, oxazolidinediones, succinimides, carbamazepine, barbiturates, benzodiazepines, valproic acid and its derivatives, miscellaneous antiepileptic drugs. Hypnotics: barbiturates, benzodiazepine sedative-hypnotics. Antipsychotics: first generation (phenothiazine, thioxanthene, structure-activity relationship; butyrophenone, benzamide derivatives). Second generation (benzazepine and analogues). Specific drugs, other chemical classes of antipsychotics.
VII week exercises	Limit tests for metals and anions (heavy metals: lead, iron, alkaline earth metals and related impurities: barium, calcium, magnesium; potassium, ammonia, aluminum, arsenic, chlorides, oxalates, sulfates, phosphates). Examination of organic impurities in medicinal substances - physical methods, chemical methods.
VIII week lectures	Antihistamines: histamine, chemistry, synthesis, metabolism, structure-activity relationships. Histamine receptors, first-generation H1 antihistamines (ethylene diamines, ethanolamine ethers, alkyl amines, tricyclic H1 antihistamines); second generation of non-sedating H1 antihistamines. Antihistamines for local use, histamine release inhibitors. Antiulcer drugs: H2 antihistamines, proton pump inhibitors.
VIII week exercises	A practical task for every student - laboratory examination of limit tests of solutions.
IX week lectures	Drugs affecting adrenergic neurotransmission. Biosynthesis, storage and release of catecholamine, metabolism, adrenergic receptors. Structure-activity relationships of adrenergic agonists, alpha1-agonist (phenylethanolamines, 2-arylimidazoline). Beta2-adrenergic agonists (phenylethanolamines: short-acting, long-acting; resorcinol and para monophenol derivatives).
IX week exercises	Titrations in non-aqueous medium - determination of weak organic bases, determination of salts of weak organic bases, determination of alkaline salts of weak organic acids, determination of weak organic acids.
X week lectures	Adrenergic antagonists: general structure of beta1-adrenergic receptor blockers (arylethanolamines and aryloxypropanolamines) and stereochemistry. Classification: nonselective (propranolol and other drugs) and cardioselective beta blockers; lipophilicity and metabolism of beta blockers. Medicines with mixed action - α/β adrenergic antagonists: labetalol, carvedilol. Blockers of alpha1-adrenergic receptors: natural and semi-synthetic ergot alkaloids, non-selective alpha-antagonists (phenoxybenzamine); selective alpha1-antagonists (prazosin and related drugs).
X week exercises	Titrations in non-aqueous medium - practical examples.
XI week lectures	Antihypertensive drugs. Classification: adrenergic neuron blocking drugs (reserpine, guanidine derivatives); centrally acting sympatholytic (methyldopa, clonidine); selective alpha1-antagonists (prazosin and related drugs); blockers of beta1-adrenergic receptors; vasodilators (directly acting - hydralazine; drugs that act on ion channels for potassium: minoxidil, diazoxide; drugs that act by releasing NO - nitroprusside); calcium channel blockers; drugs that act on the renin-angiotensin system
XI week exercises	Identification of substances with nitrogen: barbiturate derivatives (barbitone, barbitone-Na, phenobarbitone, phenobarbitone-Na), xanthine derivatives (caffeine, theophylline, theobromine, pentoxifylline), primary aromatic amines (anesthesin, sulfopreparations, urotropin); aminoalcohols, anilides, imidazoline and 3-imidazolin-5-one derivatives (aminophenazone, propyphenazone, phenazone, metamizole sodium, paracetamol, phenacetin, lidocaine hydrochloride; xylometazoline hydrochloride, ephedrine hydrochloride.
XII week lectures	Agents affecting the renin-angiotensin pathway, mechanism of action, structure-activity relationships. Angiotensin-converting enzyme inhibitors: captopril, dicarboxylate-containing inhibitors, phosphonate-containing inhibitors (fosinopril). Angiotensin II receptor blockers, mechanism of action, physical-chemical properties, structure-action relationship.
XII week exercises	Identification of nitrogen-free substances: aromatic acids and derivatives (salicylic acid, Na-salicylate; acetylsalicylic acid, phenylsalicylate, benzoic acid, Na-benzoate), aliphatic acids and derivatives (citric acid, Na-citrate, tartaric acid, Ca-gluconate, ascorbic acid), carbohydrates (glucose, lactose, sucrose, starch).
XIII week lectures	Antiarrhythmic drugs. Normal physiologic action of hearth. Classification of antiarrhythmic drugs: class I-sodium channel blockers (IA, IB, IC), class II (beta1-adrenergic receptor blockers), class III (potassium channel blockers); class IV (calcium channel blockers). Vasodilators: coronary (organic nitrates, nitric oxide donors-molsidomine) and peripheral. Calcium channel antagonists. Mechanism of calcium transport and deposition, chemical division: 1,4-dihydropyridines (physical-chemical properties, structure-activity relationship), verapamil, diltiazem.
XIII week exercises	Anxiolytic drugs-benzodiazepines, antidepressants, reuptake inhibitors of serotonin and adrenaline.
XIV week lectures	Cardiac glycosides: chemistry (cardenolide, bufadienolide), biochemical mechanism, Digitalis, Strophantus. Diuretics. Drug classes: osmotic diuretics, carbonic anhydrase inhibitors, benzothiadiazine (thiazide diuretics), Henle loop diuretics, mineralocorticoid receptor antagonists, potassium-sparing diuretics. Antihyperlipoproteinemic drugs. Lipoprotein and transport of cholesterol and triglycerides, classification of hyperlipoproteinemia. Bile acid adsorbents, fibrates, HMGCoA reductase inhibitors, cholesterol absorption inhibitors-ezetimibe. Platelet aggregation inhibitors (phosphodiesterase inhibitors, glycoprotein IIb/IIIa receptor antagonists), thrombolytics. Anticoagulants (per os, heparin and analogues).
XIV week exercises	Cardiovascular drugs-adrenergic drugs, beta-blockers, vasodilators.
XV week lectures	Review of material and preparation for the exam.
XV week exercises	Diuretics, antihypertensives, vasodilators, ACE inhibitors, antiarrhythmics.

Student workload
Per week	Per semester
9 credits x 40/30=12 hours and 0 minuts 4 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 5 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 12 hour(s) i 0 minuts x 16 =192 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 12 hour(s) i 0 minuts x 2 =24 hour(s) i 0 minuts Total workload for the subject: 9 x 30=270 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 54 hour(s) i 0 minuts Workload structure: 192 hour(s) i 0 minuts (cources), 24 hour(s) i 0 minuts (preparation), 54 hour(s) i 0 minuts (additional work)
Student obligations	Lectures and laboratory work attendance.
Consultations
Literature	1. Foyes Principles of Medicinal Chemistry. 7th ed. Williams DA, Lemke TL, editors. Baltimore: Lippincott Williams & Wilkins; 2013. 2. Wilson and Gisvolds Textbook of Organic Medicinal and Pharmaceutical Chemistry. 12th ed. Beale JM, Block JH, editors. Philadelphia: Lippincott Williams & Wilkins; 2011. 3. Radulović D, Vladimirov S. Farmaceutska hemija I. Beograd; 2005. 4. European Pharmacopoeia. 11th Edition. Strasbourg: Council of Europe; 2023. 5. Z. Vujić, J. Brborić, O. Čudina, S. Erić, B. Ivković, K. Vučićević, B. Marković; Priručnik za praktičnu nastavu iz farmaceutske hemije I i II, Beograd, 2004.
Examination methods	Class attendance (0-5). Laboratory work (0-25); Colloquia (0-20); Written exam (0-50). Pass rate for exam: 50, cumulative.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL TECHNOLOGY I

Course:

PHARMACEUTICAL TECHNOLOGY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6773	Obavezan	6	9	3++5

Programs	PHARMACY
Prerequisites	Does not have
Aims	Familiarity with the basic principles of formulation, technological production procedures and pharmaceutical-technological tests of various pharmaceutical forms for internal and external use, for application to the nose, ear and oral mucosa and with homeopathic preparations. Training for the preparation of magisterial and galenic drugs/preparations, use of professional literature and reporting on the choice of the most suitable pharmaceutical form of the drug, its properties, storage and application
Learning outcomes	1. Recognize different types, properties and roles of auxiliary substances in the production of pharmaceutical forms of drugs; 2. Recognize the types and characteristics of different pharmaceutical preparations (powders for oral use, powders for skin application, granules, liquid preparations for oral use, liquid preparations for skin application, nasal preparations, ear preparations, preparations for oral mucosa and homeopathic preparations); 3. Make the mentioned pharmaceutical preparations; 4. Carry out pharmaceutical-technological and biopharmaceutical tests of the mentioned pharmaceutical preparations.
Lecturer / Teaching assistant	Asst. Dr. Tanja Vojinović
Methodology	Lectures, laboratory exercises, consultations, practical preparations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Definition of subject, importance and general terms. Pharmacopoeias and other professional literature. Types and role of excipients in the formulation of pharmaceutical forms. Waters for pharmaceutical use
I week exercises	Acquaintance with: Legal regulations in the field of pharmaceutical activity; Pharmacopoeia (general part and special part), prescription and dispensing of medicines - doctors prescription, basic parts of the prescription, doses and dosing of medicines, preparation and dispensing of magisterial and galenic medicines; principles of Good Pharmacy Practice, Pharmacy (pharmacy activities, pharmacy premises and equipment, labeling and storage of pharmaceutical substances and medicines in the pharmacy).
II week lectures	Formulation, production and pharmaceutical technological testing of powders for internal and external use
II week exercises	Powders for oral use and powders for application to the skin. Multi-dose (undivided) powders (checking the correctness of dosage, production, packaging, signing and use of the preparation).
III week lectures	Formulation, production and pharmaceutical technological testing of solutions for internal and external use
III week exercises	Powders for oral use and powders for application to the skin. Single-dose (divided) powders (checking the correctness of dosage, production, packaging, signing and use of the preparation).
IV week lectures	Liquid and semi-solid preparations for the oral mucosa. Pharmaceutical forms for nose and ear
IV week exercises	Liquid preparations for application on the skin (checking the correctness of the dosage, production, packaging, signing and use of the preparation).
V week lectures	Extraction. Extraction methods. Extracts and tinctures. Syrups.
V week exercises	Liquid preparations for oral use (checking the correctness of dosage, production, packaging, signing and use of preparations).
VI week lectures	Formulation, production and pharmaceutical technological testing of emulsions for internal and external use. Colloquium I
VI week exercises	Production of preparations for the ears and preparations for the nose (checking the correctness of the dosage, production, packaging, signing and use of the preparations.
VII week lectures	Formulation, production and pharmaceutical technological testing of suspensions for internal and external use
VII week exercises	Preparation of preparations for the oral mucosa (checking the correct dosage, preparation, packaging, signing and use of the preparation).
VIII week lectures	Formulation, production and pharmaceutical technological testing of ointments
VIII week exercises	Semi-solid preparations for application on the skin - ointments (checking the correctness of dosage, production, packaging, signing and use of preparations).
IX week lectures	Formulation, production and pharmaceutical technological testing of creams
IX week exercises	Semi-solid preparations for application on the skin - creams (checking the correctness of dosage, production, packaging, signing and use of preparations).
X week lectures	Formulation, production and pharmaceutical technological testing of gels
X week exercises	Semi-solid preparations for application on the skin - gels (checking the correct dosage, production, packaging, signing and use of preparations).
XI week lectures	Pastes, healing plasters
XI week exercises	Semi-solid preparations for application on the skin - pastes (checking the correct dosage, production, packaging, signing and use of preparations)
XII week lectures	Homeopathic preparations/medicines
XII week exercises	Homeopathic preparations - production methods
XIII week lectures	Rheological behavior of pharmaceutical preparations. Colloquium II
XIII week exercises	Rheological tests
XIV week lectures	Practical exam
XIV week exercises	Make up for the practical exam
XV week lectures	Final exam
XV week exercises	Make up for the final exam

Student workload	Weekly 9 credits x 40/30 = 12.37 hours Structure: 3 hours of lectures, 5 hours of exercises and 4.37 hours of individual student work (preparation for laboratory exercises, colloquiums, homework) including consultations In the semester Teaching and final exam: (12.37 hours) x16= 197.92 hours Necessary preparation before the beginning of the semester (administration, registration, certification) 2 x (12.37 hours) = 24.74 hours Total workload for the course 9x30 = 270 hours Additional work for exam preparation in the remedial exam period, including remedial exam - 47.34 hours Load structure: 197.92 hours (teaching) + 24.74 hours (preparation) + 47.34 hours (additional work)=270 hours
Per week	Per semester
9 credits x 40/30=12 hours and 0 minuts 3 sat(a) theoretical classes 5 sat(a) practical classes 0 excercises 4 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 12 hour(s) i 0 minuts x 16 =192 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 12 hour(s) i 0 minuts x 2 =24 hour(s) i 0 minuts Total workload for the subject: 9 x 30=270 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 54 hour(s) i 0 minuts Workload structure: 192 hour(s) i 0 minuts (cources), 24 hour(s) i 0 minuts (preparation), 54 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises
Consultations	With the subject teacher according to the established terms Weekly
Literature	1. European Pharmacopoeia (Ph. Eur.) 10th Edition 2019. 2. Vuleta G., Milić J., Primorac M., Savić S., Farmaceutska tehnologija I. Beograd. 2012. 3. Vasiljević D., Krajičnik D., Grbić S., Đekić Lj., Farmaceutska tehnologija I praktikum.Beograd. 2012. 4. Đurić Z., Farmaceutska tehnologija sa biofarmacijom, I deo, Nijansa Zemun. Beograd. 2004. 5. Jovanović M., Praktikum iz farmaceutske tehnologije sa biofarmacijom, I deo, Nijansa Zemun. Beograd. 2003; 6. Vuleta G., Farmaceutska tehnologija sa biofarmacijom, priručnik za praktičnu nastavu: emulzije, suspenzije, polučvrsti preparati za spoljašnju upotrebu. Nauka. Beograd. 2007. 7. Allen L.V. Popovich N.G. Ansel H.C., Ansel s Pharmaceutical Dosage Forms and Drug Delivery Systems, Ninth edition, Lippinciot Williams and Wilkins. Philadelphia. 2011. 8. Swarbrick J., Encyclopedia of Pharmaceutical Technology, Third edition, Informa Healthcare USA, New York. 2007. 9. Vasiljević D., Đekić Lj., Krajišnik D., Pantelić I. Priručnik za praktičnu nastavu iz farmaceutske tehnologije. Beograd. 2019.
Examination methods	- Attendance and activity during lectures: 0-5 points - Practical lessons: 0-5 points - Colloquium I and II: (0-10)+(0-10) points - Practical part of the exam: (0-20) points - Final exam: 0-50 points Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50
Special remarks	Does not have
Comment	Additional information for the subject can be obtained from the subject teacher.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL STATISTICS

Course:

PHARMACEUTICAL STATISTICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7619	Obavezan	7	2	1+1+0

Programs	PHARMACY
Prerequisites	Mathematics
Aims	Adoption of the basic concepts and methods of statistics, analysis and interpretation of statistical results.
Learning outcomes	1. understand and explain data presented in tabular and graphical form ; 2. Show knowledge of basic concepts of statistics (relevant population sample, etc.) and its related topics, including descriptive statistics, statistical analysis, data collection techniques, concepts of probability theory and the relevance of certain factors in statistical analysis (such as random event, random variation, distribution function, distribution density); 3.show understanding of concepts related to numerical characteristics of random variables and the corresponding statistical terms (mathematical prediction, different median/mean values, dispersion), with the independent ability to conduct a survey on a population set and present the findings; 4. display knowledge in the analysis of statistical data, with the ability to formulate a parametric statistical hypothesis and of the methods to test hypotheses; 5.draw conclusions about the numerical characteristics of population based on a sample, to comprehend the meaning of numerical characteristics of the sample and the value of parametric tests; 6.to formulate a non-parametric statistical hypothesis and to undertake appropriate tests, showing comprehension of methods of linear regression and analysis of variance; 7. propose and carry-out complex statistical analysis in collaboration with professional statisticians; 8. use the knowledge acquired to identify problems and short-comings and actively participate in eradicating them.
Lecturer / Teaching assistant	Doc. dr Goran Popivoda
Methodology	Lectures, seminars, consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Population and sample. Editing and presentation of data.
I week exercises	Presentation of statistical data. Using the appropriate software.
II week lectures	Definition of probability. Conditional probability. Examples.
II week exercises	Definition of probability. Conditional probability. Examples.
III week lectures	Random variable. Examples.
III week exercises	Random variable. Examples.
IV week lectures	Mathematical expectation. Dispersion. Standard deviation. Examples.
IV week exercises	Mathematical expectation. Dispersion. Standard deviation. Examples.
V week lectures	Binomial distribution. Normal distribution.
V week exercises	Binomial distribution. Normal distribution.
VI week lectures	Students distribution. Hi-square distribution.
VI week exercises	Students distribution. Hi-square distribution.
VII week lectures	Statistical measures (measures of central tendency, measures of variability).
VII week exercises	Statistical measures (measures of central tendency, measures of variability).
VIII week lectures	Test.
VIII week exercises	Test.
IX week lectures	Confidence intervals. Examples.
IX week exercises	Confidence intervals. Examples.
X week lectures	Testing of statistical hypothesis. Examples.
X week exercises	Testing of statistical hypothesis. Examples.
XI week lectures	Testing of statistical hypothesis - second part. Examples.
XI week exercises	Testing of statistical hypothesis - second part. Examples.
XII week lectures	Nonparametric tests. Example.
XII week exercises	Nonparametric tests. Example.
XIII week lectures	Correctional test.
XIII week exercises	Correctional test.
XIV week lectures	Correlation of random variables.
XIV week exercises	Correlation of random variables.
XV week lectures	Linear and nonlinear regression.
XV week exercises	Linear and nonlinear regression.

Student workload	1 class of lectures, 1 class of seminars, 1 hour and 10 minutes of individual work
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 0 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Attendance at lectures and seminars, solving the test and the final exam.
Consultations	As agreed with the professor or teaching assistant.
Literature	1. Z. Lozanov-Crvenković, Statistika u farmaciji, Univerzitet u Novom Sadu, Medicinski fakultet, 2007; 2. A. Škrbo, J. Pandžo, D. Završnik, Statistika za farmaceute, Univerzitet u Sarajevu, Farmaceutski fakultet, 2004
Examination methods	Activity on classes 10 points, Test 40 points, Final exam 50 points. Grading scale: F (below 50 points), E (50-60 points), D (61-70 points), C (71-80 points), B (81-90 points), E (91-100 points)
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHYTOTHERAPY

Course:

PHYTOTHERAPY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7617	Obavezan	7	4	2++2

Programs	PHARMACY
Prerequisites	Pharmacognosy II
Aims	Acquiring knowledge about the place and role of phytotherapy in the system of self-medication, information about medical, dietary and cosmetic products with active components of plant origin, as well as in more detail information about different categories of medicinal products (herbal medicines and traditional herbal medicines) to their characteristics, quality parameters, control and registration (theoretical and practical aspects). Providing information about plants and herbal ingredients and medicines used in certain conditions and diseases. Information on postmarketing activities and pharmacovigilance of herbal medicines.
Learning outcomes	After the lectures and exercises, students will acquire the knowledge and skills to: 1. Know the place of phytotherapy in prevention and treatment with herbal preparations and legal regulations in the overall system of self-medication; 2. Evaluates and observes the place of rational phytotherapy in the health care system; 3. Knows the use of plants throughout history, traditional use of medicinal plants, evidence-based phytotherapy, safety and efficacy of herbal medicines; 4. Knows herbal drugs, herbal medicine, traditional medicine, standardized herbal medicine and the main active components of herbal medicine; 5. Uses acquired knowledge in the application of herbal preparations for functional disorders and organic systems (cardiovascular, gastrointestinal, respiratory, nervous, urological, metabolic, skin and mucous membrane, immune system, etc.); 6. Recognizes potential interactions between herbal and conventional medicines; 7. Informs and gives recommendations on the use of herbal medicine for a specific disease; 8. Knows how to register herbal medicine and published monographs in EP, EMEA, WHO.
Lecturer / Teaching assistant	Dr sci. med. Miloš Krivokapić
Methodology	Interactive lectures, practical classes, seminars, colloquiums, consultations whenever possible necessary. At the consultations, all dilemmas concerning the lectures and the practical part are clarified classes, as well as elaboration of topics related to additional topics or seminar papers.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Self-medication and phytotherapy. Herbal products.
I week exercises	Getting to know herbal products, terms - phytotherapy, phytopreparations, herbal and traditional medicines herbal medicines; training students how to find additional information through the review documentation of laws and regulations.
II week lectures	Herbal medicines and registration of herbal medicines.
II week exercises	Registration of herbal medicines in neighboring countries and some European countries.
III week lectures	Chemical-pharmaceutical-biological control of herbal medicines.
III week exercises	Regulations, methods according to monographs for the control of herbal medicines.
IV week lectures	Application of herbal medicines in the therapy of diseases of the nervous system - anxiety, depression, cognitive disorders.
IV week exercises	Presentation of cases, patients, with anxiety disorders, mild to moderate depression and cognitive disorders and the place of herbal medicine in the mentioned diseases.
V week lectures	Application of herbal medicines in diseases of the heart and blood vessels.
V week exercises	Pharmacist-patient simulation in finding herbal medicine for use in cardiovascular disease.
VI week lectures	Use of herbal medicines in diseases of the gastrointestinal tract.
VI week exercises	Presentation of cases with gastrointestinal disease.
VII week lectures	Colloquium. Use of herbal medicines for constipation and diarrhea.
VII week exercises	Treatment of problems with constipation and diarrhea.
VIII week lectures	Application of herbal medicines in metabolic disorders.
VIII week exercises	Presentation of cases with metabolic problems.
IX week lectures	Use of herbal medicines during menopause.
IX week exercises	Herbal remedies to ease discomfort during menopause.
X week lectures	Application of herbal medicines in benign prostatic hyperplasia.
X week exercises	Presentation of cases with benign prostatic hyperplasia.
XI week lectures	The use of herbal medicines in the therapy of urological diseases.
XI week exercises	Herbal remedies to alleviate urological problems.
XII week lectures	Application of herbal medicines in skin therapy and skin diseases.
XII week exercises	Presentation of cases in skin therapy and skin diseases.
XIII week lectures	Interactions, adverse reactions and pharmacovigilance of herbal medicines.
XIII week exercises	Presentation of cases with side effects of herbal medicines.
XIV week lectures	Tests of compounds and natural medicines in order to discover new pharmacologically active compounds.
XIV week exercises	Herbal medicines as potential compounds for the treatment of malignant diseases.
XV week lectures	Final exam.
XV week exercises	Make up from the final exam.

Student workload	In the semester Teaching and final exam (5 hours and 30 minutes) x 16 = 85 hours and 20 minutes Necessary preparations before the beginning of the semester (administration, registration, certification) 2 x 5 hours and 30 minutes = 11 hours Total course load: 4 x 30 = 120 hours. Additional work: 24.20 hours Structure of workload: 84.80 hours (teaching) + 11 hours (preparation) + 24.20 hours (additional work) = 120 hours.
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises.
Consultations	Consultations take place by agreement with students.
Literature	1. Heinrich M, Barnes J, Gibbons S, Elizabeth MW. Fundamentals of Pharmacognosy and Phytotherapy, 3rd Edition. Churchill Livingstone; 2018 2. Capasso F, Gaginella TS, Grandolini G, Izzo AA. Phytotherapy. Handbook of herbal medicine. Novi Sad: Prometheus; 2005 3. Nikolić Z. Traditional medicine: phytotherapy - holistic medicine. Don Vas Belgrade; 2017 4. Tucakov J. Healing with herbs. Volcano Belgrade; 2014 5. Kovačević N. Basics of pharmacognosy. Faculty of Pharmacy, Belgrade; 2004 6. Pelagić V. Pelagićs folk teacher. Leo commerce; 2014 7. Schulz V, Haensel R, Tyler VE. Rational Phytotherapy. Springer-Verlag, Berlin, 2001. 8. Blumenthal M. The ABC Clinical Guide to Herbs. American Botanical Council, Austin, 2003. 9. ESCOP Monographs. 2nd ed. Exeter: The European Scientific Cooperative on Phytotherapy; Stuttgart: Georg Thieme Verlag; New York: Thieme New York, 2003.
Examination methods	Activities during lectures, assessment of practical classes, presentations, seminar papers, colloquium, final exam. Pre- examination requirements: 50 points; Attendance at lectures (0-5) points; Exercise activity and exercise preparation (0-15); Colloquium from the theoretical part of the material (0-10 points); Colloquium from the practical part of the material (0-20 points). Final exam: 0-50 points A passed exam implies a cumulative total of 50 points and more.
Special remarks	Theoretical teaching takes place for all students together, practical teaching in groups of no more than 15 students.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / COSMETOLOGY

Course:

COSMETOLOGY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7616	Obavezan	7	5	2++2

Programs	PHARMACY
Prerequisites	None
Aims	Introduction to legal regulations on cosmetic ingredients (raw materials), cosmetic and dermocosmetic products, key ingredients for the production of cosmetic and dermo-cosmetic products, types and forms of cosmetic and dermo-cosmetic products, procedures for the production and testing of selected groups of cosmetic and dermo-cosmetic products, effects of cosmetic and dermo-cosmetic products on the skin and its appendages, providing adequate advice and recommendations on the use and possible side effects of cosmetic and dermo-cosmetic products.
Learning outcomes	1. Familiar with the legal regulations on cosmetic products and dermocosmetic preparations; 2. Defines types and forms of cosmetic products; 3. Understands the procedures for the production and quality testing of cosmetic and dermocosmetic preparations; 4. Identifies the effects of cosmetic products on the skin and its appendages; 5. Informs the patient about the action of cosmetic products and provides advice on their selection and application; 6. Recognizes potential unwanted effects of cosmetic products
Lecturer / Teaching assistant	Zorica Potpara, PhD, Assoc. Prof and Nataša Radonjić, MPharm, teaching assist.
Methodology	Interactive lectures, and practical training (preparation of formulations according to a prescription after diagnosing the cause of skin damage).

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Definition and history of cosmetology, its connection to medicine and pharmacy
I week exercises	Historical overview of the development of cosmetology with the viewing of educational films
II week lectures	Legal regulations related to the quality of raw materials, production conditions, registration, testing, and circulation of medical and decorative cosmetics
II week exercises	Practical assessment of the quality of cosmetic raw materials used in the production of medical and decorative cosmetics
III week lectures	Raw materials used in the production of cosmetic products
III week exercises	Familiarization with domestic and foreign legal regulations related to the quality assessment of raw materials
IV week lectures	Skin care and cleansing products
IV week exercises	Practical preparation of formulations with selected cosmetic raw materials for application to the skin
V week lectures	Dermocosmetic products for sun protection
V week exercises	Quality assessment and selection of appropriate filters when creating sun protection formulations
VI week lectures	Hair care products, deodorants, and antiperspirants
VI week exercises	Practical review of the potential health hazards of certain excipients found in hair care products, deodorants, and antiperspirants
VII week lectures	Dermocosmetic products for baby skin care
VII week exercises	Overview of the structure of baby skin and practical preparation of formulations for application to baby skin
VIII week lectures	Cosmetic products for teeth and oral cavity
VIII week exercises	Assessment of new technologies used in the production of products for oral cavity application
IX week lectures	Decorative cosmetics
IX week exercises	Practical preparation of decorative cosmetic products
X week lectures	Acne, types, and causes
X week exercises	Observation of educational films on the types and causes of acne, practical preparation of formulations for the treatment of certain forms of acne
XI week lectures	Methods of treating acne
XI week exercises	Cosmetic assessment of new products on the market used in acne treatment
XII week lectures	Diseases manifested on the skin, how to recognize them, and how to care for the skin in such cases
XII week exercises	Practical preparation of formulations for the care of diseased skin
XIII week lectures	Fragrance and the history of manufacturing technology
XIII week exercises	Overview of perfume manufacturing technology
XIV week lectures	Soaps, fragrances, aromatic oils, aromatherapy
XIV week exercises	Practical preparation of soaps and aromatic oils
XV week lectures	Exam preparation
XV week exercises	Final practical exam

Student workload	Weekly 5 credits x 40/30 = 6.66 hours Structure: 2 hours of lectures and 2 hours of exercises 2.66 hours of independent work and consultation. Teaching and final exam: (6.66 hours) x 16 = 106.66 hours. Necessary preparations before the beginning of the semester (administration, enrollment, verification): (6.66 hours) x 2 = 13.33 hours Total workload for the course: 5 x 30 = 150 hours. Workload structure: 106.66 hours (teaching and final exam) + 13.33 hours (preparation) + 30 hours (additional work)
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 2 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	Attendance to theoretical and practical classes is mandatory. Preparation and presentation of seminars are obligatory.
Consultations	Consultations are conducted with the subject teacher and associates at the specified time
Literature	Vasiljević D, Savić S, Đorđević LJ, Krajišnik D, Handbook of cosmetology, Nauka, Belgrade, 2009. Rieger MM, Harry Cosmetology, 2000, 8th ed, Chemical Publishing Co, Inc, New York. Vuleta G, pharmaceutical technology with biopharmacy - manual for practical teaching: emulsions, suspensions, semi-solid preparations for external use, Nauka, Belgrade, 2007. Review and professional papers from domestic and international journals (Archive for Pharmacy, Int J Cosmet Sci, Cosmetic and Toiletries, Cosmetic Dermatology)
Examination methods	Attendance at lectures: (0-5) points Attendance and activity at exercises: (0-15) points Seminar: (0-10) points Test: (0-20) points Final exam: (0-50) points Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50
Special remarks	Additional information about the subject can be obtained from the subject teacher.
Comment	None

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOTHERAPY I

Course:

PHARMACOTHERAPY I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7618	Obavezan	7	5	2++2

Programs	PHARMACY
Prerequisites	Pharmacology I, Pharmacology II
Aims	Adoption of the current theoretical and practical expertise in clinical medicine, as well as enable students to apply the acquired knowledge in professional and scientific research. Development of critical thinking and implementation of diagnostic and therapeutic procedures, as well as developing the capacity for teamwork.
Learning outcomes	1. Understand basic principles of rational pharmacotherapy; 2. Understand and differentiate patho-physiological, clinical presentation, clinical course, prognosis, pharmacological and non- pharmacological treatment of various diseases; 3. Compare the relationship between therapeutic efficiency / potential to the relative known side-effects on the choice of drugs intended for treatment of the same disease; 4. explain the use, benefits and risks of the drug.
Lecturer / Teaching assistant	Snežana Mugoša, MD, MSc, PhD (teacher)
Methodology	Interactive lectures, practical classes, colloquia.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Pulmology - clinical symptomatology of pulmonary disease, diagnostic methods in pulmonology, pharmacotherapy of pulmonary disease
I week exercises	Medical history taking. The role of pharmacists in the treatment of pulmonary disease (anamnesis, approach to patients, rational pharmacotherapy, case reports).
II week lectures	Gastroenterology - Functional and organic diseases of the gastrointestinal tract, symptoms, diagnosis and pharmacotherapy.
II week exercises	The role of pharmacists in the treatment of gastroenterological diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports)
III week lectures	Pharmacotherapy of emesis, constipation and diarrhea.
III week exercises	The role of pharmacists in the treatment of diseases of emesis, constipation and diarrhea.(anamnesis, approach to patients, rational pharmacotherapy, case reports).
IV week lectures	Cardiology - Hypertension. Angina pectoris. Acute coronary syndrome
IV week exercises	The role of pharmacists in the treatment of cardiac disease (anamnesis, approach to patients, rational pharmacotherapy, case reports).
V week lectures	Heart failure. Arrhythmias.
V week exercises	The role of pharmacists in the treatment of heart failure and arrhythmias (medical history, approach to patients, rational pharmacotherapy, case reports).
VI week lectures	Transplantation immunology and clinical aspects. Immune system disorders.
VI week exercises	The role of pharmacists in transplantation immunology and the treatment of disorders of the immune system (anamnesis, approach to patients, rational pharmacotherapy, case reports).
VII week lectures	Introduction to diabetes mellitus - etiopathogenesis, stages of development and clinical manifestations of diabetes mellitus type 1 and type 2.
VII week exercises	The role of pharmacists in the treatment of diabetes mellitus type 2 (anamnesis, approach to patients, rational pharmacotherapy, case reports).
VIII week lectures	Treatment of diabetes mellitus. The insulin types and dosages. Acute and chronic complications of diabetes.
VIII week exercises	The role of pharmacists in the treatment of diabetes mellitus type 1 (anamnesis, approach to patients, rational pharmacotherapy, case reports).
IX week lectures	Endocrinology - Endocrine hypothalamus, pituitary gland, thyroid gland, pheochromocytoma.
IX week exercises	The role of pharmacists in the treatment of endocrine diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
X week lectures	Diseases of parathyroid glands and gonads.
X week exercises	The role of pharmacists in the treatment of diseases of the parathyroid glands and gonads (medical history, approach to patients, rational pharmacotherapy, case reports).
XI week lectures	Hormonal contraceptives and hormone substitution therapy.
XI week exercises	Hormonal contraceptives (combined contraceptives, monocomponent contraceptives, indications, dosage regimens, safety of use, contraindications) Hormonal substitution therapy (advantages and disadvantages; contraindications)
XII week lectures	Nephrology - Clinical syndromes and classification of glomerulopathies. Pyelonephritis. Nephrotic syndrome. Renal insufficiency. Nephrolithiasis.
XII week exercises	The role of pharmacists in the treatment of nephrology diseases (medical history, approach to patients, rational pharmacotherapy, case reports).
XIII week lectures	Hematology - Anemia. Antiaggregation drugs, anticoagulants, fibrinolytics. Therapy of thromboembolic disorders.
XIII week exercises	The role of pharmacists in the treatment of hematological diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XIV week lectures	Pharmacotherapy of hyperlipidemia and dyslipidemia.
XIV week exercises	The role of pharmacists in the treatment of hyperlipidemia and dyslipidemia (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XV week lectures	Oncology - Pharmacotherapy protocols in cancer therapy.
XV week exercises	Approach to the patient with cancer. The role of the pharmacist in the treatment of malignant disease (anamnesis, rational pharmacotherapy, case reports).

Student workload	Teaching and the final exam: 5.3hx16=84.8h Necessary preparation (before semester enrolment, etc.) 2hx5.3=10.6 Total work hours for course: 4x30=120h
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 2 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	The presence and active participation in the theoretical and practical training, as well as all forms of assessment is required.
Consultations	The course lecturer and teaching assistants held consultations with students once a week in the period which is defined at the beginning of academic year.
Literature	Nenad Ugrešić, Radica Stepanović-Petrović, Miroslav Savić. Farmakoterapija za farmaceute, Farmaceutski fakultet Beograd, 2021. Igor Francetić. Farmakoterapijski priručnik, Medicinska naklada Zagreb, 2011. Tomislav Kažić. Klinička farmakologija. Farmakoterapija. Integra, 2011.
Examination methods	Lecture Attendance: 0-5 points. Colloquium I: 0-40 points. Preparation and presentation of the seminar: 0-5 points; Final exam (0-50 points) Final exam is oral. Minimum Cumulative Grade Point is 50 points and more.
Special remarks	None.
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL TECHNOLOGY II

Course:

PHARMACEUTICAL TECHNOLOGY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7614	Obavezan	7	7	3++3

Programs	PHARMACY
Prerequisites	Does not have
Aims	Familiarity with the basic principles of formulation, technological production procedures and pharmaceutical-technological tests of various pharmaceutical forms for internal and external use, for application to the nose, ear and oral mucosa and with homeopathic preparations. Training for the preparation of magisterial and galenic drugs/preparations, use of professional literature and reporting on the choice of the most suitable pharmaceutical form of the drug, its properties, storage and application.As part of the course, students will also be introduced to the basics of biopharmaceutical technology, including the formulation, stability, storage, and application of biological medicines such as proteins, peptides, vaccines, monoclonal antibodies, and biosimilars. Biological medicines will be covered through dedicated lectures and practical sessions, with a focus on their specific requirements in manufacturing, testing, and application.
Learning outcomes	1. Knows the types, composition, manufacturing/production procedures, pharmaceutical-technological tests and pharmacopoeia requirements for pharmaceutical forms of drugs for parenteral and ophthalmic use; 2. Recognizes the types, properties and roles of pharmaceutical excipients in the production of the mentioned pharmaceutical forms; 3. Formulates and manufactures the specified pharmaceutical forms and proposes and/or conducts certain pharmaceutical-technological tests of these drugs; 4. Knows and understands the principles related to the influence of biopharmaceutical (biological, physical-chemical and pharmaceutical-technological) factors on the process of release and resorption of the medicinal substance after parenteral or ophthalmic administration of the drug; 5. Application of acquired knowledge in order to inform and advise the patient and the professional public about the properties and quality of parenteral and ophthalmic pharmaceutical forms, their storage and adequate application. 6. Applies basic knowledge in the field of information and digital technologies to data analysis, report preparation, and conducting simulations related to pharmaceutical-technological processes.
Lecturer / Teaching assistant	Asst. Dr. Tanja Vojinović
Methodology	Lectures, laboratory exercises, consultations, practical preparations.The use of information technologies includes the application of software tools for formulation simulation, electronic databases for monitoring drug stability, as well as digital documentation and reporting.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Sterilization. Pyrogenic substances and testing of pyrogenicity
I week exercises	Sterilization, pyrogenicity test-discussion.
II week lectures	Methods of sterilization
II week exercises	Getting to know the principles of preparation under aseptic conditions in a chamber with laminar air flow.
III week lectures	Isotonic solutions
III week exercises	Getting to know the methods for checking and adjusting the tonicity of the preparation, i.e. calculating the required amount of isotonization agent
IV week lectures	Pharmaceutical forms for ophthalmic use: basic concepts, definitions Eye preparations.
IV week exercises	Production of eye drops under aseptic conditions in a chamber with laminar air flow, checking the concentration, checking the tonicity of the preparation, packaging, signing and use.
V week lectures	Pharmaceutical forms for ophthalmic use: auxiliary substances for the preparation of eye preparations, properties and general requirements
V week exercises	Semi-solid eye preparations. Manufacturing under aseptic conditions in a chamber with laminar air flow, packaging, signing and use of eye ointment.
VI week lectures	Production and testing of eye preparations Semi-solid eye preparations.
VI week exercises	Manufacturing under aseptic conditions in a chamber with laminar air flow, packaging, signing and use of eye ointment.
VII week lectures	Parenteral preparations: basic terms, definitions.Colloquium I.
VII week exercises	Parenteral preparations: solvents, excipients and general requirements.
VIII week lectures	Parenteral preparations. Expression of content of parenteral preparations. Production, packaging and labeling of parenteral preparations.
VIII week exercises	Parenteral preparations discussion and calculation for the preparation of parenteral preparations.
IX week lectures	Injections. Intravenous infusions
IX week exercises	Parenteral preparations.Preparation of the injection solution in a chamber with laminar air flow, checking the tonicity, calculating the required amount of substances for preparation, packaging, signing.
X week lectures	Concentrates for injections and infusions. Powders for injections and infusions
X week exercises	Parenteral preparations. Preparation of the infusion solution in a chamber with laminar air flow, checking the tonicity, calculating the required amount of substances for preparation, packaging, signing, action and use of the preparation.
XI week lectures	Primary packaging for parenteral and ophthalmic preparations
XI week exercises	Parenteral preparations. Production in a chamber with laminar air flow, tonicity check, calculation of the required amount of substances for preparation, packaging, signing, action and use of the preparation.
XII week lectures	Solutions for hemodialysis and peritoneal dialysis.Colloquium II
XII week exercises	Solutions for hemodialysis and peritoneal dialysis.
XIII week lectures	Immunobiological preparations. Serums and vaccines
XIII week exercises	Immunobiological preparations. Serums and vaccines production methods - discussion.
XIV week lectures	Biopharmaceutical technology and biological medicines: characteristics, challenges, stability, and testing. Radiopharmaceutical preparations.
XIV week exercises	Handling and packaging of biological medicines, quality control.
XV week lectures	Modern pharmaceutical forms: biotechnological medicines, monoclonal antibodies, and biosimilars – technological characteristics and stability challenges.
XV week exercises	Discussion: practical handling of biological medicines – sterility, packaging, and storage of mAbs and biosimilars.

Student workload	Weekly 7 credits x40/30 = 9 hours 30 minutes. Structure: 3 hours of lectures, 3 hours of exercises and 3 hours and 30 minutes of independent work. In the semester Classes and final exam (9.30 hours x 16 = 149.20 hours) Necessary preparations before the beginning of the semester (administration, registration, certification): 2x (9 hours and 30 minutes) = 19 hours Total workload for the course 7 x 30 = 210 hours. Additional work: 42.20 hours Load structure: 149.20 hours (teaching) + 19 hours (preparation) + 42.20 hours (additional work) = 210 hours
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises
Consultations	Consultations with the subject teacher according to established terms
Literature	1. European Pharmacopoeia (Ph. Eur.) 12th Edition 2025. 2. Milić J., Primorac M., Stupar M. Priručnik za praktičnu nastavu: Sterilni lekoviti preparati, Grafopan, Beograd 2005. 3. Krajišnik D., Grbić S., Petrović J., Đekić Lj., Vasiljević D., Kovačević A., Calija B. Farmaceutska tehnologija II praktikum, Beograd.2010 4. Allen L.V. Popovich N.G. Ansel H.C. Ansel s Pharmaceutical Dosage Forms and Drug Delivery Systems, Ninth edition, Lippinciot Williams and Wilkins. Philadelphia. 2011 5. Swarbrick J., Encyclopedia of Pharmaceutical Technology, Third edition, Informa Healthcare USA, New York. 2007. 6. Gibson M., Pharmaceutical Preformulation and Formulation, Informa Healthcare USA, New York. 2009. 7. Krajišnik D., Đekić Lj., Cvijić S., Vasiljević D. Univerzitet u Beogradu. 2020. 8. Vranić E., Hadžiabdić J., Elezović A., Rahić O. Farmaceutska tehnologija.Problemski zadaci I rješenja II. Univerzitet u Sarajevu Farmaceutski fakultet.Sarajevo 2018. 9. Handbook of Pharmaceutical Technology.2022. 10. Advances in Pharmaceutical Biotechnology. Springer. 2020.
Examination methods	Attendance and activity during lectures: 0-5 points - Practical lessons: 0-5 points - Colloquium I and II: (0-10)+(0-10) points - Practical part of the exam: (0-20) points - Final exam: 0-50 points Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50
Special remarks	Does not have
Comment	Additional information for the subject can be obtained from the subject teacher.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARAMACEUTICAL ANALISYS AND MEDICINES CONTROL

Course:

PHARAMACEUTICAL ANALISYS AND MEDICINES CONTROL/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7615	Obavezan	7	7	3++3

Programs	PHARMACY
Prerequisites	Pharmaceutical chemistry III
Aims	Acquisition of knowledge in the field of qualitative and quantitative pharmaceutical analysis and its application in drug quality control. Testing and control of pharmaceutical substances and dosage forms according to official regulations. Familiarization with basic principles, regulations, and standards in the field of drug quality control. Special emphasis is placed on the use of digital tools and software in analytical measurement and data processing, aiming to develop digital literacy in laboratory settings.
Learning outcomes	Apply acquired knowledge in routine quality control of pharmaceutical substances and dosage forms; Explain and apply pharmacopeial requirements for testing pharmaceutical substances and dosage forms; Select appropriate methods for drug quality control; Demonstrate and explain the importance of development and validation of new methods; Interpret and apply current regulatory requirements in drug quality control.
Lecturer / Teaching assistant	Tijana Mićović
Methodology	Lectures, practical exercises, consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to Qualitative and Quantitative Drug Analysis. Pharmaceutical Analysis and Quality Control of Pharmaceutical Substances and Dosage Forms. European Pharmacopoeia Quality Standards.
I week exercises	Determination of aminophylline in tablets. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
II week lectures	Pharmaceutical Analysis – theoretical part of practical training.
II week exercises	Determination of ampicillin in capsules. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
III week lectures	Application of UV/VIS Spectrophotometry in Pharmaceutical Analysis.
III week exercises	Determination of cephalexin in capsules. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
IV week lectures	Significance and Application of IR Spectrophotometry in Pharmaceutical Analysis. Polarimetry and Testing of Optically Active Drugs. Refractometry in Pharmaceutical Analysis. Melting Point Determination.
IV week exercises	Determination of metoclopramide hydrochloride in tablets. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
V week lectures	Identification, purity testing, and content determination of active pharmaceutical substances using chromatographic methods. High-Performance Liquid Chromatography (HPLC) in Pharmaceutical Analysis.
V week exercises	Determination of molsidomine in tablets. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
VI week lectures	hin Layer Chromatography (TLC); Gas Chromatography (GC); Gel Chromatography; Affinity Chromatography; and Ion Chromatography in identification, purity testing, and content determination of active pharmaceutical substances in pharmaceutical forms and active substances.
VI week exercises	Determination of ibuprofen and paracetamol in tablets. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
VII week lectures	Colloquium I
VII week exercises	Determination of pipemidic acid in capsules. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
VIII week lectures	Liquid-liquid and liquid-solid extraction in pharmaceutical analysis. Titrimetric methods in pharmaceutical analysis.
VIII week exercises	Determination of acetylsalicylic acid in tablets. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
IX week lectures	Testing and control of alkaloids in pharmaceutical substances and dosage forms.
IX week exercises	Determination of resorcinol in solution. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
X week lectures	Testing and control of vitamins in pharmaceutical substances and dosage forms.
X week exercises	Determination of tetracycline in capsules. Assessment of linearity, accuracy, and precision of the method using UV/VIS technique. Digital processing of spectrophotometry data.
XI week lectures	Pharmaceutical analysis and quality control of antibiotics in pharmaceutical substances and dosage forms. Pharmaceutical analysis and quality control of sulfonamides in pharmaceutical substances and dosage forms.
XI week exercises	Titrimetric exercises. Determination of content of Li₂CO₃, KCl, CaCl₂, NaCl, and ascorbic acid.
XII week lectures	Colloquium II
XII week exercises	hin-layer chromatography. Determination of impurity content in specific preparations, e.g., hydrocortisone with hydrocortisone acetate as an impurity.
XIII week lectures	Pharmaceutical analysis and quality control of steroid drugs in pharmaceutical substances and dosage forms.
XIII week exercises	Solid-phase extraction. Separation of a mixture of methyl orange and fuchsine.
XIV week lectures	Official testing of inorganic compounds. Biological control of drugs.
XIV week exercises	HPLC – high-performance liquid chromatography, qualitative analysis of paracetamol, acetylsalicylic acid, and salicylic acid as an impurity in oral powder formulations. Digital processing of chromatography data.
XV week lectures	Final exam
XV week exercises	Evaluation of practical work. Independent analysis of a selected preparation.

Student workload
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Attendance and active participation in both theoretical and practical classes, as well as in all forms of knowledge assessment, is mandatory.
Consultations
Literature	European Pharmacopoeia, važeće izdanje; EU Legislation – Eudralex; European Medicines Agency – scientific guidelines (quality); ICH quality guidelines; EDQM&HealthCare (European Directorate for the Quality of Medicines and HealthCare); Satinder Ahuja and Stephen Scypinski, Handbook of modern Pharmaceutical analysis, Volume 3, 2001, Academic press, San Diego, USA; H.J.Roth, Kurt Eger, Reinhard Troschutz, Pharmaceutical Chemistry, Volume 2: Drug Analysis, English Edition, Ellis Horwood, 1991; Odabrane metode za farmaceutsku analizu, dr Ljiljana Živanović, Nijansa, Zemun, 2003; Analitika lekova, udžbenik za laboratorijsku nastavu, Darko Ivanović, Mira Zečević, Anđelija Malenović, Beograd 2004.
Examination methods	Pre-exam obligations: 50 points; attendance at lectures (0-6); activity in exercises and completion of exercises (0-12); midterms (0-18 + 0-14); Final exam is written (0-50 points). Passing grade is achieved by accumulating a minimum of 50 points.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / DERMATOCOSMETICS PREPARATIONS

Course:

DERMATOCOSMETICS PREPARATIONS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7620	Obavezan	8	2	1+1+0

Programs	PHARMACY
Prerequisites	None
Aims	Expanding the knowledge base of students on the category of dermocosmetic preparations (DKP), which are very present in public pharmacies, knowledge of legislation in the field of dermo-cosmetics in the EU and a new category of dermo-cosmetic products, the acquisition of skills to recognize the key ingredients dermo-cosmetic products (NCI name), their effects, in regarding the types of products, provide adequate advice on how to use and possible side effects, the introduction of new carriers for cosmetic active substances
Learning outcomes	1. use professional terminology and inform potential users of the use and possible adverse effects of dermocosmetic preparations; 2. know EU legislation and the INCI names of ingredients of different groups of such preparations; 3. understand and apply acquired knowledge about the characteristics, composition, methods of production and testing the most important groups within this field; 4. inform others of new developments in the field of dermo-cosmetics and their relative attributes; 5. know the groups of excipient substances and carriers of modern cosmetically active ingredients in making preparations.
Lecturer / Teaching assistant	Prof. dr Zorica Potpara
Methodology	Lectures, colloquiums, problem-based learning

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Definition, characteristics DCMS
I week exercises	Explanation of basic definitions and characteristics DCMS
II week lectures	DKP differences compared to cosmetic products and drugs
II week exercises	Practically spotting the differences in relation to DKP cosmetic products and drugs
III week lectures	The legislation of the EU and the US for the DKP (impact assessment, safety and tolerability)
III week exercises	Computer-legislation, and organizing workshops on this subject
IV week lectures	Categories DCMS
IV week exercises	The practical distinction between categories DCMS
V week lectures	The mechanism of the aging and photoaging,oxidative stress
V week exercises	Evaluation of the factors that cause premature aging of the skin and practical preparation of the DCM for slowing the aging process of the skin
VI week lectures	Formulation of new products for the prevention and treatment of photo-aging skin
VI week exercises	Practical making preparations for the prevention and treatment of skin photoaging
VII week lectures	Ingredients (raw materials) in the formulation of the DCM (NCI: antioxidants, the new KAS)
VII week exercises	Introducing students to choose appropriate and quality raw material in the formulation of DCM
VIII week lectures	Groups of excipients (emollients, new emulsifiers, polymers)
VIII week exercises	Introducing students to the types and roles of the excipients in the preparation DCMS
IX week lectures	Contemporary carriers KAS in dermo-cosmetic preparations
IX week exercises	Review of the most important characteristics of modern carrier KAS in dermo-cosmetic preparations
X week lectures	Dermo-cosmetic preparations for the prevention and treatment of skin with Acne
X week exercises	Practical preparation of dermocosmetic preparations for the prevention and treatment of skin with Acne
XI week lectures	Dermo-cosmetic products for dry skin
XI week exercises	Practical making preparations for the treatment of dry skin
XII week lectures	Evaluation of the effectiveness and safety of dermocosmetic / cosmetic products in vivo and in vitro methods
XII week exercises	Practical making preparations for sun protection
XIII week lectures	Dermocosmetic preparations for problematic skin
XIII week exercises	Practical making preparations for problematic skin
XIV week lectures	Dermocosmetic preparation for the treatment of certain conditions of problematic skin-Example
XIV week exercises	The practical production of preparations for the treatment and discussion of recipes for the treatment of certain states of problematic skin
XV week lectures	Preparation for final exam
XV week exercises	Preparation for final exam

Student workload	Weekly 2 credits x 40/30 = 2,6 hours. Structure:1 hour of lectures, 1 hour of practical work, 1 hour of independent work. Lectures and final exam ( 2,6 hours x16=42h). Necessary preparations before the semester begins( administration, enrolment) 2 hours x 2,6=5,2h. Total workload for subject:2 hours x 30 =60h. Supplementary work 12,8 hours. Structure of workload 42+5,2+12,8=60 hours
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 0 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Attendance to lectures and practical part is obligatory. Writing and presenting seminar papers is obligatory and it is assessed
Consultations	Professor and teaching associates have consultations with students once a week in the period defined at the beginning of the academic year
Literature	Vasiljević D,Savić S,Krajišnik D,Đekić Lj,.Priručnik iz kozmetologije.Nauka,Beograd,2009.Rieger MM.,Harry’s Cosmeticology.,2000,8th ed.,Chemical Publishing Co.,Inc.,New York. De Polo KFD .,A short textbook of cosmetology.1998,1st ed.,H.Ziolkowsky GmbH ,A
Examination methods	The presence of classes (0-5 points) Practical instruction and Active (0-10 points) Case reports: (0-15 points) Test: (0-20 points) The final test: (0-50 points)
Special remarks	Curriculum and the timetable of the subject must be followed
Comment	Additional information can be given by the professor

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARAMACEUTICAL ETHICS AND LAW

Course:

PHARAMACEUTICAL ETHICS AND LAW/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7628	Obavezan	8	3	3++0

Programs	PHARMACY
Prerequisites	None
Aims	Mastering the fundamentals of applied ethics in pharmacy necessary for analyzing and solving problems in pharmaceutical healthcare practice and biomedical research, as well as in marketing and industrial production; Understanding the practical importance of ethics in pharmaceutical practice and recognizing the differences between ethical and legal issues; Developing critical thinking skills for ethical analysis in specific situations in pharmaceutical practice (problem identification, selection of ethical concepts, and justification of decisions based on that selection); Raising awareness of the social role of the pharmaceutical profession, professional ethics, and the importance of the social context in providing pharmaceutical care and health education.
Learning outcomes	The student will learn to: Apply laws, by-laws, and other regulations that govern all aspects of pharmaceutical practice; Understand the difference between legal and ethical issues encountered in professional pharmaceutical work; Apply ethics and legal principles to current issues and resolve problems using ethical analysis; Apply ethical principles in the pharmaceutical industry and drug marketing; Understand and ethically reason about patients’ moral values and rights; Use normative ethics in preclinical, clinical, and biomedical research; Be aware of the social responsibility of the profession, the role of pharmacists in healthcare, and the principles of social pharmacy, including community health, rational use of medicines, and access to medicines for different population groups; Distinguish and apply ethical principles in the context of pharmaceutical care, social justice, and the professional relationship with the patient; Critically assess ethical dilemmas when working with vulnerable groups and in situations with limited resources; Demonstrate professional and ethical communication within a multidisciplinary healthcare team.
Lecturer / Teaching assistant	Zorica Potpara, PhD, Assoc. Prof
Methodology	Interactive lectures and practical classes (workshops: case analysis from practice, problem-based learning; panel discussions, tests).

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Normative ethics in pharmacy. Introduction to ethics, the definition of ethics in pharmacy
I week exercises	Introduction to ethics, the definition of ethics in pharmacy
II week lectures	Ethical principles, ethical theories, and ethical norms relevant to the pharmacy profession. Content analysis and practical application
II week exercises	Basic concepts, ethical norms, practical examples, and analyses
III week lectures	Ethical analysis of cases from pharmaceutical health practice - moral values, faulty reasoning. Pharmacy mistakes - moral and criminal responsibility of pharmacists.
III week exercises	Panel discussions on moral reasoning and mistakes in pharmaceutical practice
IV week lectures	Ethical reasoning in respecting the moral values and rights of patients. Ethics in counseling and providing pharmaceutical care to patients with chronic illnesses, the elderly, pregnant women, and individuals with mental health disorders. Principles of accessibility, equity, and personalization of healthcare.
IV week exercises	Most common examples on the topic of patient rights
V week lectures	Ethics in preclinical and clinical drug trials. The role and importance of the ethics committee. Biomedical research in developing countries
V week exercises	Examples of clinical trials and biomedical drug research
VI week lectures	Ethics in the pharmaceutical industry and drug marketing
VI week exercises	Discussions and examples of ethics in industry and drug marketing
VII week lectures	European and international drug regulations - basic guidelines
VII week exercises	Familiarization with legal regulations, and defining basic guidelines. Test
VIII week lectures	National health policy and regulation in healthcare (law on health care, health insurance, health chambers).
VIII week exercises	Comments, panel discussions on the most important articles of the mentioned laws
IX week lectures	The right to access medicines and healthcare – how ethics and social pharmacy protect the most vulnerable groups. Resource distribution, drug shortages, fairness, and solidarity.
IX week exercises	Case studies: Ethical dilemma during a drug shortage – who should receive the medication when supply is limited?
X week lectures	Regulatory procedures at the Institute for Medicines and Medical Devices
X week exercises	Defining procedures and discussions on the topic of drug registration
XI week lectures	Pharmaceutical regulations (national sublegal acts and professional rules).
XI week exercises	Pharmaceutical regulations (national sublegal acts and professional rules).
XII week lectures	Pharmacist license
XII week exercises	Criteria for obtaining pharmacist licenses
XIII week lectures	Application of Ethics and Law to Current Issues (drug testing, suicide, placebo, euthanasia, confidentiality of patient and medication information)
XIII week exercises	Practical case examples.
XIV week lectures	The Role of the Pharmacist in Promoting Vaccination, Preventing Drug Abuse, and Combating Misinformation. Ethical Challenges in Counseling during Public Campaigns.
XIV week exercises	harmacist participation in a diabetes prevention campaign – how to communicate ethically with patients?
XV week lectures	Disciplinary Board
XV week exercises	Presentation of seminar papers.

Student workload
Per week	Per semester
3 credits x 40/30=4 hours and 0 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 1 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 4 hour(s) i 0 minuts x 16 =64 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 4 hour(s) i 0 minuts x 2 =8 hour(s) i 0 minuts Total workload for the subject: 3 x 30=90 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 18 hour(s) i 0 minuts Workload structure: 64 hour(s) i 0 minuts (cources), 8 hour(s) i 0 minuts (preparation), 18 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance at lectures and practical parts of the course. Continuous acquisition of knowledge and skills.
Consultations	Consultations according to the established schedule with the subject teacher
Literature	ICH regulativa i regulativa Evropske unije koje se odnose na sve aspekte lijeka, zdravstvenog osiguranja i prava i obaveza farmaceuta u pružanju farmaceutske zdravstvene zaštite. 2. Aktuelni zakoni i podzakonska akta Crne Gore iz oblasti zdravstva 3. Parojčić D., Etika u farmaciji: Nikolin i sar. Galerija farmaceutskih veština. Beograd: Placebo, 301-347, 2005. 4. Veatch R., Haddad A., Case Studies in pharmacy ethics. New York: Oxford University Press; 5. Beachamp T.L., Childress J.F. Principles of Biomedical Ethics (5th ed) New York: Oxford University Press.
Examination methods	Attendance at lectures: 0–10 points Practical classes (seminars, panel discussions): 0–25 points Test: 0–15 points Final exam: 0–50 points
Special remarks	None
Comment	Additional information about the subject can be obtained from the subject teacher

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BIOPHARMACEUTICS

Course:

BIOPHARMACEUTICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7627	Obavezan	8	4	1+2+0

Programs	PHARMACY
Prerequisites	Pharmacology I and II
Aims	Introduction in biopharmacy. Relationship between phisico-chemical characteristics of API and bioavailibility. Introduction into biopharmaceutical aspects of dosage forms and methods of biopharmaceutical characterization of API and dosage form.
Learning outcomes	1. define physiological, physico-chemical and pharmacological factors affecting drug release from the pharmaceutical form; 2. apply acquired knowledge in the formulation of limited solubility and low-permeability drug substances; 3. define the class of any given medicinal substance according to the biopharmaceutical classification system, enabling a pharmaceutically suitable form to be proposed and evaluated; 4. undertake biopharmaceutical testing of a pharmaceutical form.
Lecturer / Teaching assistant	Asst. Dr. Tanja Vojinović
Methodology	Interactive lectures, practical course, seminars

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction. Definitions. Posology - influence on biopharmaceutical characteristics. Dosage form - influence on biopharmaceutical characteristics.
I week exercises	Effects of dosage form on bioavailability of the API
II week lectures	Influence of formulation of dosage form on biopharmaceutical characteristics. Drug release. Drug distribution. Drug metabolism and elimination.
II week exercises	Calculation of half life of API elimination
III week lectures	Factors affecting drug release and absorption
III week exercises	Drug release kinetics
IV week lectures	Influence of biological factors on drug absorption.
IV week exercises	Drug transfer mechanisms. Drug application and absorption.
V week lectures	Resorption through the mucous membranes of the mouth and stomach.
V week exercises	Calculating the partition coefficient
VI week lectures	Oral use. Parenteral application of drugs. Resorption through the lungs. Application to the skin. Application to the mucous membranes.
VI week exercises	Drug release test
VII week lectures	Free week
VII week exercises	Free week
VIII week lectures	First colloquium. The influence of physical and chemical factors on the release and absorption of medicinal substances. The degree of ionization and pH. Coefficient of water-lipid distribution. Solubility. Dissolution rate. Particle size.
VIII week exercises	Solubility determination of API
IX week lectures	Polymorphism and pseudopolymorphism. Salt formation. Complexing and adsorption.
IX week exercises	Biopharmaceutical classification system
X week lectures	Surfactants. Viscosity. Stability of the drug substance in body fluids.
X week exercises	Compendial apparatus for drug release study
XI week lectures	The influence of pharmaceutical and technological factors on the release and absorption of medicinal substances.
XI week exercises	Rotating paddle apparatus
XII week lectures	Biopharmaceutical factors of the dosage form. Oral dosage forms. Rectal dosage forms.
XII week exercises	Rotating basket apparatus
XIII week lectures	Parenteral dosage forms. Dermopharmaceuticals
XIII week exercises	Flow through apparatus
XIV week lectures	In vitro investigation of the kinetics of drug substance release from formulations. Influence of: temperature, solvent; pH value of solvent, presence of enzymes.
XIV week exercises	Drug release profile comparison.
XV week lectures	Application of membranes. Methods for drug release testing from solid drug formulations. Membrane models. Tests for absorption monitoring.
XV week exercises	Calculation of the kinetics of drug substance release from formulations

Student workload	5.3 hours
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 2 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	1 hour of lectures 2 hours of practical
Consultations	2,3 hours of consultation
Literature	Đurić Z., Birmančević M. Farmaceutska tehnologija sa biofarmacijom, prvi dio, Naučna knjiga, Beograd, 2004.; Parojčić J., Ibrić S., Đurić Z., Farmaceutska tehnologija sa biofarmacijom, priručnik za praktičnu nastavu, 2006 European Pharmacopoeia, 9th edit
Examination methods	Attendance at lectures: (0-5 points) Attendance and activity at exercises: (0-10 points) Colloquium I: (0-20 points) Seminar work: (0-15 points) Final exam: (0-50 points) The final exam is taken in writing.
Special remarks	Does not have
Comment	All necessary information for the subject can be obtained from the subject teacher

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOTHERAPY II

Course:

PHARMACOTHERAPY II/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7624	Obavezan	8	5	2+0+2

Programs	PHARMACY
Prerequisites	Pharmacology I, Pharmacology II
Aims	Adoption of the current theoretical and practical expertise in clinical medicine, as well as enable students to apply the acquired knowledge in professional and scientific research. Development of critical thinking and implementation of diagnostic and therapeutic procedures, as well as developing the capacity for teamwork.
Learning outcomes	1. Recognize various cardiovascular diseases, infectious diseases, diabetes, kidneys and liver diseases, osteoporosis - all on the basis of medical history and laboratory test results; 2. Recognize psychiatric disorders, gynecological disorders, respiratory and rheumatic diseases all on the basis of medical history and analysis of laboratory data; 3. Apply pharmacological and non-pharmacological treatments to the same diseases; 4. estimate the relationship of therapeutic efficiency / potential to the risk of adverse side-effects of medicines for the treatment of a given disease.
Lecturer / Teaching assistant	Snežana Mugoša, MD, MSc, PhD (teacher)
Methodology	Interactive lectures, practical classes, colloquia.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Neurology - Clinical symptoms, diagnostic procedures, pharmacotherapy of neurological diseases.
I week exercises	The role of pharmacists in the treatment of neurological diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
II week lectures	Epilepsy and Parkinsons disease.
II week exercises	The role of pharmacists in the treatment of Epilepsy and Parkinsons disease (anamnesis, approach to patients, rational pharmacotherapy, case reports).
III week lectures	Multiple sclerosis. Alzheimers disease. Headaches.
III week exercises	The role of pharmacists in the treatment of multiple sclerosis. Alzheimers disease and headaches (anamnesis, approach to patients, rational pharmacotherapy, case reports).
IV week lectures	Psychiatry - Clinical symptoms, diagnostic procedures, pharmacotherapy of psychiatric disorders
IV week exercises	The role of pharmacists in the treatment of mental disorders (anamnesis, approach to patients, rational pharmacotherapy, case reports).
V week lectures	Psychosis. Depression. Anxiety.
V week exercises	The role of pharmacists in the treatment of psychosis, depression and anxiety (anamnesis, approach to patients, rational pharmacotherapy, case reports).
VI week lectures	Infectious diseases - clinical symptomatology of infectious diseases, diagnostic methods and pharmacotherapy.
VI week exercises	The role of pharmacists in the treatment of infectious diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
VII week lectures	Pharmacotherapy of the human immunodeficiency virus infection. Pharmacotherapy of viral hepatitis.
VII week exercises	The role of pharmacists in pharmacotherapy of the human immunodeficiency virus infection and viral hepatitis.
VIII week lectures	Gynecology and obstetrics - Clinical symptoms, diagnostic procedures, pharmacotherapy of gynecological diseases.
VIII week exercises	The role of pharmacists in the treatment of gynecological disorders (anamnesis, approach to patients, rational pharmacotherapy, case reports).
IX week lectures	Oral contraception. Pharmacotherapy of sexual dysfunction.
IX week exercises	The role of pharmacists in oral contraception and pharmacotherapy of sexual dysfunction (anamnesis, approach to patients, rational pharmacotherapy, case reports).
X week lectures	Rheumatic diseases - clinical symptomatology of rheumatic diseases, diagnostic methods, pharmacotherapy of rheumatic diseases.
X week exercises	The role of pharmacists in pharmacotherapy of rheumatic diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XI week lectures	Systemic connective tissue diseases. Degenerative diseases.
XI week exercises	The role of pharmacists in pharmacotherapy of systemic connective tissue diseases and degenerative diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XII week lectures	Eye diseases - clinical symptomatology eye diseases, diagnostic methods, pharmacotherapy of eye diseases. Glaucoma. Eye infections.
XII week exercises	The role of pharmacists in pharmacotherapy of eye diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XIII week lectures	Dermatovenerology - Clinical symptoms, diagnostic procedures, pharmacotherapy of skin diseases.
XIII week exercises	The role of pharmacists in pharmacotherapy of skin diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XIV week lectures	Pharmacotherapy of autoimmune diseases of the skin. Skin infections.
XIV week exercises	The role of pharmacists in pharmacotherapy of autoimmune diseases of the skin and skin infections (anamnesis, approach to patients, rational pharmacotherapy, case reports).
XV week lectures	Pharmacotherapy of sexually transmitted diseases.
XV week exercises	The role of pharmacists in pharmacotherapy of sexually transmitted diseases (anamnesis, approach to patients, rational pharmacotherapy, case reports).

Student workload	Teaching and the final exam: 5.3hx16=84.8h Necessary preparation (before semester enrolment, etc.) 2hx5.3=10.6 Total work hours for course: 4x30=120h
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 2 sat(a) theoretical classes 2 sat(a) practical classes 0 excercises 2 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	The presence and active participation in the theoretical and practical training, as well as all forms of assessment is required.
Consultations	The course lecturer and teaching assistants held consultations with students once a week in the period which is defined at the beginning of academic year.
Literature	Nenad Ugrešić, Radica Stepanović-Petrović, Miroslav Savić, Farmakoterapija za farmaceute, Farmaceutski fakultet Beograd 2021. Igor Francetić. Farmakoterapijski priručnik, Medicinska naklada Zagreb 2011. Lawrence i Benett. Klinička farmakologija 2002;
Examination methods	Lecture Attendance: 0-5 points. Colloquium I: 0-40 points. Preparation and presentation of the seminar: 0-5 points; Final exam (0-50 points) Final exam is oral. Minimum Cumulative Grade Point is 50 points and more.
Special remarks	None.
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / TOXICOLOGY WITH ANALYTICS

Course:

TOXICOLOGY WITH ANALYTICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7626	Obavezan	8	6	2++3

Programs	PHARMACY
Prerequisites	None
Aims	Gaining the knowledge on different fields of toxicology (general toxicology, forensic toxicology, professional toxicology, clinic toxicology, toxicology of food, toxicology of drugs, ecotoxicology, analytic toxicology…) with the aim to improve the health and safety of living beings and the protection of their environment.
Learning outcomes	1. apply acquired knowledge about drug toxicity and the recreational use of drugs; 2. apply the acquired knowledge in the field of poisoning through occupational hazard; 3. apply the acquired knowledge in the field of environmental pollution, clinical toxicology and forensic toxicology; 4. know regulatory toxicology in relation to dispensing and the role of pharmacists in the health system.
Lecturer / Teaching assistant	Dr sci. med. Vera Dabanović
Methodology	Lectures, laboratory work, consultation

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	History, Poison definition, Doses, Groups of poisons, Factors determining toxicity
I week exercises	Analysis of carbon monoxide in blood
II week lectures	The fate of poisons in the organism, Toxicokinetics, Mechanisms of toxicity, Types of poisoning
II week exercises	Analysis of sulfur dioxide in air sample
III week lectures	Toxicodynamics-target organ toxicity, Basics of mutagenicity, teratogenicity and carcinogenicity
III week exercises	Analysis of nitrogen oxides in air sample
IV week lectures	Basics principles of poisoning therapy and antidotes, Toxicological analysis from sampling to results interpretation
IV week exercises	Analysis of methanol in alcoholic beverage
V week lectures	Gaseous poisons: carbon monoxide, carbon dioxide, sulfur dioxide, nitrogen oxides, chlorine, hydrogen sulfide
V week exercises	Analysis of ethanol in blood
VI week lectures	Volatile poisons: cyanides, alcohols, carbon disulfide, benzene and benzene derivates
VI week exercises	Analysis of benzene in air sample; Analysis of phenol in urine
VII week lectures	Volatile poisons: chlorinated carbohydrates, persistent organic pollutants
VII week exercises	Analysis of parathion in blood
VIII week lectures	Mineral poisons. Metals: arsenic, mercury, lead, cadmium. I colloquium
VIII week exercises	Analysis of mercury in food
IX week lectures	Manganese, thallium. Fluorides. Corrosives
IX week exercises	Analysis of lead in blood or urine
X week lectures	Herbal and synthetic poisons. Alkaloides. Heterosides
X week exercises	Analysis of mangane in water
XI week lectures	Drug poisoning. Psychoactive controlled substances
XI week exercises	Analysis of fluoride in urine or water
XII week lectures	Pesticides
XII week exercises	Detection of herbal and synthetic poisons in urine
XIII week lectures	Principles of ecotoxicology. II colloquium
XIII week exercises	Analysis of salicylate in urine
XIV week lectures	Toxicological Risk Assessment. Regulatory affairs in toxicology
XIV week exercises	Practical exam
XV week lectures	Finale exam
XV week exercises

Student workload	Weekly: 6 credits x 40/30 = 8 hours and 40 minutes Structure: 2 hours of lectures, 3 hours of exercises, 3 hours and 40 minutes of independent work During the semester Classes and final exam 8.40 hours x 16 = 134.4 hours. Necessary preparations before the beginning of the semester (registration, certification...) 8.40 x2 = 16.8 hours. Total load: 6 x 30= 180 h Additional work 28.8 h Load structure: 134.4 hours (teaching) + 16.8 hours (preparation) + 28.8 hours (additional work) = 180 hours
Per week	Per semester
6 credits x 40/30=8 hours and 0 minuts 2 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 8 hour(s) i 0 minuts x 16 =128 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 8 hour(s) i 0 minuts x 2 =16 hour(s) i 0 minuts Total workload for the subject: 6 x 30=180 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 36 hour(s) i 0 minuts Workload structure: 128 hour(s) i 0 minuts (cources), 16 hour(s) i 0 minuts (preparation), 36 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises
Consultations
Literature	1. Timbrell J. Introduction to Toxicology. 3rd ed. New York: Taylor & Francis; 2001. 2. Casarett & Doulls Toxicology: The Basic Science of Poisons. 7th ed. Klaassen CD, editor. New York: McGraw‐Hill Professional; 2008. 3. Gossel TA, Bricker JD.: Princi
Examination methods	Grading system: Pre-exam obligations: 50 points Class Participation (0-8); Practical classes (0-6); Practical exam (0-10); I i II colloquium (0-26) (0-13)+(0-13) Final written exam: 0- 50 points
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL TECHNOLOGY III

Course:

PHARMACEUTICAL TECHNOLOGY III/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7623	Obavezan	8	7	2++3

Programs	PHARMACY
Prerequisites	Does not have
Aims	Getting to know the types, composition, manufacturing processes and pharmaceutical-technological testing of pharmaceutical forms for rectal and vaginal use, aerosols, solid pharmaceutical forms, preparations with modified release of the medicinal substance and therapeutic systems
Learning outcomes	The student is expected to: 1. Recognize different types, properties and roles of auxiliary substances in the production of solid pharmaceutical forms of drugs; 2. Recognize the types and characteristics of different solid pharmaceutical preparations (capsules, tablets, pellets, preparations with modified drug release, suppositories and vagitories, inhalation preparations); 3. Make solid pharmaceutical preparations; 4. Perform pharmaceutical-technological and biopharmaceutical tests of solid pharmaceutical preparations.
Lecturer / Teaching assistant	Asst. Dr. Tanja Vojinović
Methodology	Lectures, laboratory exercises, consultations, practical preparations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Rectal pharmaceuticals forms
I week exercises	Introduction labaratory exercises
II week lectures	Vaginal pharmaceutical forms
II week exercises	Production of rectal preparations; determination of displacement factor
III week lectures	Aerosols
III week exercises	Production of vaginal preparations
IV week lectures	Properties of powders important for the production of solid pharmaceutical forms
IV week exercises	Liquid preparations for inhalation; Powders for inhalation; Pharmaceutical preparations packed under pressure (Aerosols)
V week lectures	Capsules
V week exercises	Production and testing of capsules
VI week lectures	Capsules
VI week exercises	Production of calcium-alginate hydrogel microparticles by in situ gelation process; examination of swelling ability and pH sensitivity of calcium-alginate microparticles
VII week lectures	Colloquium I. Pellet
VII week exercises	Production and testing of granules
VIII week lectures	Tablets, definitions, properties, general characteristics
VIII week exercises	Production and testing of tablets
IX week lectures	Types of tablets
IX week exercises	Production and testing of tablets
X week lectures	Excipients for making tablets
X week exercises	Examination of the dissolution rate of medicinal substances from solid pharmaceutical forms
XI week lectures	Methods for making tablets
XI week exercises	Biopharmaceutical characterization of drugs; solubility test; determination of the partition coefficient
XII week lectures	Examining tablets
XII week exercises	Pharmaceutical-technological tests of tablets
XIII week lectures	Colloquium II. Preparations with modified release of medicinal substance
XIII week exercises	General considerations when designing preparations with modified release of medicinal substance
XIV week lectures	Therapeutic systems for oral administration of drugs
XIV week exercises	Technologies for oral administration of drugs
XV week lectures	Preparations for the Final Exam
XV week exercises	Practical exam

Student workload	Weekly 6 credits x 40/30 = 8 hours and 40 minutes. Structure: 2 hours of lectures, 3 hours of exercises, 3 hours and 40 minutes of independent work . In the semester Classes and final exam 8.40 hours x 16 = 134.4 hours. Necessary preparations before the beginning of the semester (registration, certification...) 8.40 x2 = 16.8 hours. Total load: 6 x 30= 180 h Additional work 28.8 h Load structure: 134.4 hours (teaching) + 16.8 hours (preparation) + 28.8 hours (additional work) = 180 hours
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 2 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 4 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises
Consultations	Consultations with the subject teacher according to established terms
Literature	1. European Pharmacopoeia (Ph. Eur.) 10th Edition 2019. 2. Đurić Z. Pharmaceutical technology with biopharmacy, Part I, Nyansa, Zemun, 2004. 3. Parojčić J., Ibrić S., Đurić Z. Pharmaceutical technology with biopharmacy (Biopharmacy-Tablets-Capsules), manual for practical teaching, Konstisi, Belgrade, 2006. 4. Allen L.V. Popovich N.G. Ansel H.C., Ansels. Pharmaceutical Dosage Forms and Drug Delivery Systems, Ninth edition, Lippinciot Williams and Wilkins. Philadelphia. in 2011 5. Swarbrick J. Encyclopedia of Pharmaceutical Technology, Third edition, Informa Healthcare USA, New York. in 2007 6. Vranić E., Hadžiabdić J., Elezović A., Rahić O. Pharmaceutical technology. Problem tasks I solutions II. University of Sarajevo, Faculty of Pharmacy, Sarajevo 2018. 7. Đuriš J., Cvijić S., Aleksić I. Practicum in Pharmaceutical Technology III. University of Belgrade Faculty of Pharmacy. White City. in 2021
Examination methods	Attendance and activity during lectures: 0-5 points - Practical lessons: 0-5 points - Colloquium I and II: (0-10)+(0-10) points - Practical part of the exam: (0-20) points - Final exam: 0-50 points Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50
Special remarks	Does not have
Comment	Additional information for the subject can be obtained from the subject teacher

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BIOPHARMACEUTICS WITH PHARMACOKINETICS

Course:

BIOPHARMACEUTICS WITH PHARMACOKINETICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
11860	Obavezan	8	9	4++4

Programs	PHARMACY
Prerequisites	Does not have
Aims	The student will get to know the basics of biopharmacy and understand the connection between the process of absorption, distribution, metabolism and elimination of the drug with the effect and safety of drug administration; will understand the dependence of the treatment outcome on the pharmaceutical form, the place of application and the dosage regimen of the drug. Get to know the types of pharmacokinetic data analysis for the assessment and calculation of pharmacokinetic parameters, understand the importance, principles and methods of conducting bioavailability/biological equivalency studies of medicinal preparations.
Learning outcomes	After passing the exam, the student is expected to know pharmacokinetic processes and the factors that influence them, to understand the influence of pharmaceutical-technological, physicochemical and physiological factors on the speed of drug release from pharmaceutical forms, to understand the metabolic changes of drugs and the importance of studying metabolism in the development and application of drugs . To know different approaches in pharmacokinetic data analysis and to know the principles of the biopharmaceutical drug classification system. To understand/calculate the PK parameter after a single or repeated dose of the drug for IV and half administration, to know the factors that influence the variability of the therapeutic response, to know the method of testing biological availability and biological equivalence of medicinal preparations.The student identifies and explains the specific pharmacokinetic characteristics of biopharmaceuticals and biological drugs, and applies methods for evaluating their bioavailability, bioequivalence, and therapeutic efficacy. The student uses digital tools and software platforms to calculate pharmacokinetic parameters, interpret data, and simulate drug concentration profiles in biological systems.
Lecturer / Teaching assistant	Asst. Dr. Tanja Vojinović
Methodology	Lectures, laboratory exercises, consultations, practical calculation of biopharmaceutical and pharmacokinetic parameters. The practical part involves the use of digital tools for the analysis of pharmacokinetics and biopharmaceutical characteristics of drugs. Students use software for modeling and simulating concentration–time profiles, as well as for assessing bioequivalence, thereby developing their information and digital skills relevant to pharmaceutical practice and research.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to biopharmaceutics and pharmacokinetics. Changes in drug dosage forms in the development of biopharmaceuticals. Relationship between formulation and pharmacokinetics of biopharmaceuticals.
I week exercises	Laboratory: The impact of drug dosage form on the biopharmaceutics and pharmacokinetics of biopharmaceuticals.
II week lectures	Biopharmaceutical classification system. Solubility and permeability of biopharmaceuticals – BCS applied to biological drugs.
II week exercises	Laboratory: Solubility and permeability of drugs. Biopharmaceutical classification system.
III week lectures	The impact of biological factors on the absorption of biopharmaceutical drugs. Behavior of biological molecules in the body.
III week exercises	Calculations exercises: Biological factors and solubility in drug absorption.
IV week lectures	Physico-chemical properties of the drug and medicinal form and oral bioavailability. Other routes of drug administration.
IV week exercises	Determination of the partition coefficient of the drug
V week lectures	Routes of administration of biological drugs: challenges in absorption and stability. Parenteral and mucosal administration of biopharmaceuticals.
V week exercises	Evaluation of formulation and stability of biopharmaceuticals in parenteral and mucosal administration.
VI week lectures	The influence of physical and chemical factors on the release and absorption of medicinal substances. Degree of ionization and pH values. Coefficient of water-lipid distribution. Solubility. Dissolution rate. Particle size.
VI week exercises	Examination of the dissolution rate of drugs from different pharmaceutical forms.
VII week lectures	Physicochemical properties and stability of biotechnological molecules. Stability and degradation in bodily fluids.
VII week exercises	Testing the stability of biotechnological molecules under simulated conditions.
VIII week lectures	Introduction to pharmacokinetics: basics of pharmacodynamics, therapeutic drug monitoring. Pharmacokinetic processes to which the drug in the body is subject: resorption, distribution, metabolism and excretion of drugs - ADME system. Resorption, distribution of drugs.
VIII week exercises	Calculation of similarity and difference factors in the evaluation of drug dissolution rate.
IX week lectures	Metabolism and excretion of drugs
IX week exercises	Computational tasks - calculation of pharmacokinetic parameters
X week lectures	Pharmacokinetic evaluation of biological drugs and biosimilars. Introduction to PK modeling for monoclonal antibodies and therapeutic proteins.
X week exercises	Population pharmacokinetic studies
XI week lectures	Assessment of bioavailability and bioequivalence of biological drugs. Key EMA/FDA criteria for biological therapies.
XI week exercises	Examination of bioavailability/biological equivalence of drug preparations
XII week lectures	Pharmacokinetic analysis of urine data. Biological availability/biological equivalence of drug preparations.
XII week exercises	Case analyses
XIII week lectures	Pharmacokinetic variability in biological therapies. Individual PK variation, immune response, and interactions.
XIII week exercises	Analyzes of cases in order to calculate pharmacokinetic parameters after a single dose of the drug
XIV week lectures	Determination of the initial dose and a new dose when the desired concentration was not achieved in clinical conditions
XIV week exercises	Analyzes of cases in order to calculate pharmacokinetic parameters after repeated dosing of intravenous and per os administration
XV week lectures	Multiple drug administration and the influence of pharmacokinetic parameters on the appearance of the pharmacokinetic curve in multiple drug administration.
XV week exercises	Case analyzes in order to calculate pharmacokinetic parameters when using plasma and urine as biological materials

Student workload	Weekly Weekly 9 credits x 40/30 = 12 hours and 37 minutes. Structure: 4 hours of lectures, 4 hours of laboratory exercises, 4 hours and 37 minutes of independent work, including consultations. In the semester Classes and final exam (12 hours and 37 minutes) x 16 = 198 hours and 32 minutes Necessary preparations before the beginning of the semester (administration, registration, certification) 2 x 12 hours and 37 minutes = 25 hours and 14 minutes. Total load on the course: 9 x 30 = 270 hours. Overtime: 46 hours and 54 minutes Load structure: 198.32 hours (teaching) + 25.14 hours (preparation) + 46.54 hours (additional work) = 270 hours
Per week	Per semester
9 credits x 40/30=12 hours and 0 minuts 4 sat(a) theoretical classes 4 sat(a) practical classes 0 excercises 4 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 12 hour(s) i 0 minuts x 16 =192 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 12 hour(s) i 0 minuts x 2 =24 hour(s) i 0 minuts Total workload for the subject: 9 x 30=270 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 54 hour(s) i 0 minuts Workload structure: 192 hour(s) i 0 minuts (cources), 24 hour(s) i 0 minuts (preparation), 54 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises
Consultations	Consultations with the subject teacher according to established terms
Literature	1. Đurić Z. Farmaceutska tehnologija sa bioframacijom. Nijansa Zemun. Beograd. 2004. 2. Pokrajac М., Miljković B., Vučićević K. Farmakokinetika. Farmaceutski fakultet Beograd. 2019. 3. Pokrajac М. Farmakokinetika-Priručnik za praktičnu nastavu. Beograd.2008. 4. Ritchel W, Kearns G. Handbook of basic pharmacokinetics including clinical applications. 7th ed. Washington: American Pharmacists Association. 2009. 5. European Pharmacopoeia (Ph. Eur.) 12th Edition 2025. 6. Pharmaceutical Biotechnology in Drug Development. 2023. Elsevier.
Examination methods	Attendance at lectures (0-8 points); Exercise activity and exercise preparation (0-6 points); Practical part of the exam (0-6); I and II colloquium (0-30) (0-15)+(0-15). Final exam: 0-50 points. A passing grade is obtained if a cumulative minimum of 50 points is collected Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50
Special remarks	Does not have
Comment	Additional information for the subject can be obtained from the subject teacher

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / MODERN PHARMACEUTICAL FORMULATIONS

Course:

MODERN PHARMACEUTICAL FORMULATIONS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7642	Obavezan	9	2	1+1+0

Programs	PHARMACY
Prerequisites	No
Aims	Introducing students with the types, composition and features of newer pharmaceutical forms / therapeutic systems for oral, parenteral, ophthalmic, intravenous / intrauterine, pulmonary, buccal, nasal and transdermal applications; colloidal carriers of drug substances; familiarization with concepts related to the influence of physico-chemical, biological and pharmaceutical-technological factors, on the process of release and resorption of medicinal substances from advanced pharmaceutical forms / therapeutic systems
Learning outcomes	1. recognize different types, characteristics and role of excipients in the development of modern pharmaceutical forms; 2. recognize types and characteristics of different modern pharmaceutical forms (oral dispersible tablets, oral films, wafers, micro-emulsions, nanoemulsions, implants, therapeutic systems for various routes of administration); 3. execute pharmaceutical-technological tests of certain pharmaceutical products; 4. know the mechanisms of modified release of the active ingredient.
Lecturer / Teaching assistant	Doc. dr Tanja Vojinović
Methodology	Interactive lectures, practical lessons, seminars, problem-based learning

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Contemporary aspects of the formulation of newer pharmaceutical forms / therapeutic systems
I week exercises	Contemporary aspects of the formulation of newer pharmaceutical forms / therapeutic systems
II week lectures	Mechanisms of Modified Release of the Active Substance I
II week exercises	Mechanisms of Modified Release of the Active Substance I
III week lectures	Mechanisms of Modified Release of the Active Substance II
III week exercises	Mechanisms of Modified Release of the Active Substance II
IV week lectures	Therapeutic systems for oral administration I
IV week exercises	Therapeutic systems for oral administration I
V week lectures	Therapeutic systems for oral administration II
V week exercises	Therapeutic systems for oral administration II
VI week lectures	Drug delivery systems for parenteral application
VI week exercises	Drug delivery systems for parenteral application
VII week lectures	Free week
VII week exercises	Free week
VIII week lectures	Therapeutic systems for ophthalmic and intravaginal / intrauterine applications
VIII week exercises	Therapeutic systems for ophthalmic and intravaginal / intrauterine applications
IX week lectures	Therapeutic systems for pulmonary use
IX week exercises	Therapeutic systems for pulmonary use
X week lectures	Therapeutic systems for buccal and nasal administration
X week exercises	Therapeutic systems for buccal and nasal administration
XI week lectures	Therapeutic systems for transdermal administration I
XI week exercises	Therapeutic systems for transdermal administration I
XII week lectures	Therapeutic systems for transdermal administration II
XII week exercises	Therapeutic systems for transdermal administration II
XIII week lectures	Therapeutic systems with targeted release of the drug substance
XIII week exercises	Therapeutic systems with targeted release of the drug substance
XIV week lectures	Colloid carriers of medicinal substances: liposomes
XIV week exercises	Colloid carriers of medicinal substances: liposomes
XV week lectures	Colloid carriers of medicinal substances: nanoparticles and nano / microemulsions
XV week exercises	Colloid carriers of medicinal substances: nanoparticles and nano / microemulsions

Student workload	1 hour lecture 1 hour of exercises 1 hour independent work
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 0 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	2 credits - 2,6 hours
Consultations
Literature	1. Allen L.V. Popovich, N.G. Ansel, H.C. Ansels Pharmaceutical Dosage Forms and Drug Delivery Systems, Lippincot Williams and Wilkins, Phyladelphia, 2005; 2. Remington: Science and Practice of Pharmacy, Lippincott Williams and Wilkins, 2005; 3. Encicloped
Examination methods	Attendance at lectures: (0-8 points) Practical classes: (0-12 points) Seminar paper: (0-30 points) Final exam: (0-50 points)
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / ANALYTICAL CHEMISTRY IN PHARMACEUTICAL PRACTICE I

Course:

ANALYTICAL CHEMISTRY IN PHARMACEUTICAL PRACTICE I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
8017	Obavezan	9	2	1+1+0

Programs	PHARMACY
Prerequisites	There is no conditionality
Aims	The goal is that students learn what is the real sample and how to solve specific analytical problems. Complex samples necessitate a systematic approach to the problem, so the student gets his first experience in setting up a methodology for solving specific analytical problems.
Learning outcomes	1. create a skilled approach to the analysis of real samples; 2. clearly define a problem and choose an appropriate technique for sampling, the method of sample preparation for quantitative chemical analysis; 3. select the appropriate analytical method for the analysis of inorganic ions, to test and interpret the results.
Lecturer / Teaching assistant	Assistant Professor Vesna Vukašinović-Pešić, PhD
Methodology	lectures, laboratory exercises, group work, consultations and interactive teaching (database search)

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Presentation of subject. Real sample - Application voltammetric technique in the analysis of inorganic ions - Part I
I week exercises
II week lectures	The real samples - Application voltammetric technique in the analysis of inorganic ions - Part II
II week exercises
III week lectures	The real samples - Analysis of the metals and metalloids using atomic spectroscopy methods - Part I
III week exercises
IV week lectures	The real samples - Analysis of the metals and metalloids using atomic spectroscopy methods - Part II
IV week exercises
V week lectures	Analytical applications of photometric titration and derivative spectrophotometry in the analysis of real samples - Part I
V week exercises
VI week lectures	Analytical applications of photometric titration and derivative spectrophotometry in the analysis of real samples - Part II
VI week exercises
VII week lectures	Application of potentiometry in the analysis of real samples - Part I
VII week exercises
VIII week lectures	Application of potentiometry in the analysis of real samples - Part II
VIII week exercises
IX week lectures	Application of UV/VIS spectroscopy and fluorometry in analysis of metal ions - Part I
IX week exercises
X week lectures	Application of UV/VIS spectroscopy and fluorometry in analysis of metal ions - Part II
X week exercises
XI week lectures	Interactive teaching and database search
XI week exercises
XII week lectures	Interactive teaching and database search
XII week exercises
XIII week lectures	Interactive teaching and database search
XIII week exercises
XIV week lectures	Interactive teaching and database search
XIV week exercises
XV week lectures	Final exam
XV week exercises

Student workload
Per week	Per semester
2 credits x 40/30=2 hours and 40 minuts 1 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 0 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 2 hour(s) i 40 minuts x 16 =42 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 2 hour(s) i 40 minuts x 2 =5 hour(s) i 20 minuts Total workload for the subject: 2 x 30=60 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 12 hour(s) i 0 minuts Workload structure: 42 hour(s) i 40 minuts (cources), 5 hour(s) i 20 minuts (preparation), 12 hour(s) i 0 minuts (additional work)
Student obligations	Students are required to attend lectures and practical training, to do and teach seminars.
Consultations
Literature
Examination methods	Activities during lectures (0-10 poens), laboratory exercises(0-20 poens), Seminars (0-20 poens), Final exam (0-50 poens)
Special remarks	Exercises are organized in the form of visits institutions that have the right equipment and in the form of seminars.
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL PRACTICE I

Course:

PHARMACEUTICAL PRACTICE I/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7636	Obavezan	9	4	2+2+0

Programs	PHARMACY
Prerequisites	Pharmacology II, II Pharmacognosy, Pharmaceutical Chemistry III
Aims	The role and place of pharmacists in primary, secondary and tertiary levels of health care, introduction to drugs, lists of drugs and medical devices. Introducing measures to check the quality of medicines, following the appearance of counterfeit medicines and their reporting to the competent institutions. Getting acquainted with the process of the administration of the pharmaceutical activities, the procedures for the granting of finished drugs and medical devices
Learning outcomes	1. recognize the role and place of pharmacists at the primary, secondary and tertiary level; 2. understand the distinction between branded and generic drugs and any difference in effectiveness; 3. identify verification measures to ensure quality of medicines, guarding against counterfeit medicines and their reporting to the competent institutions; 4. use acquired knowledge in the development of major and galenic drugs, the supply of finished medicines and other medical supplies; 5. make calculations, refunds and undertake general business administration; 6. know the styles and types of communication (patient, professional and general public); 7. use acquired knowledge for counselling of patients, having knowledge of the pharmaceutical history and major revisions to medical therapy to correct past error.
Lecturer / Teaching assistant	Doc. dr Tanja Vojinović
Methodology	Interactive lectures, practical part (workshops, case studies, simulation work with the recipe, making calculations and budget)

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Defining and meeting with the health system
I week exercises	Definitions of pharmaceutical practices, activities, comparison with the pharmaceutical practice in the region
II week lectures	WHO, FDA, WSMI and essential drug lists
II week exercises	Introduction to the lists of drugs, recommended by WHO and the FDA in the area of prescriptions
III week lectures	Drug list (national and hospital)
III week exercises	Panel discussions -list of drugs, examples of national drug list
IV week lectures	Public and hospital pharmacies as part of the health care system
IV week exercises	Getting to know the types of pharmacies and the activities carried out in them
V week lectures	Activities in daily practice pharmacy in the city (planning, procurement, storage, distribution)
V week exercises	Getting to know simulating pharmacy, simulation work with patients, prescribing
VI week lectures	Activities in daily practice in a hospital pharmacy
VI week exercises	Panel discussion on the topic of drugs dispensed in the hospital pharmacy and the specifics of work in a hospital pharmacy
VII week lectures	Pharmaceutical products -group, forms, qualifications
VII week exercises	Introduction to the pharmaceutical products, groups and forms
VIII week lectures	Medical devices and products serving health (preventive, diagnostic, therapeutic and rehabilitation means)
VIII week exercises	Getting acquainted with the medical facilities, types, ways of issue
IX week lectures	Prescription and issuance of finished medicines, medical devices and OTC
IX week exercises	Issuance of prescription medicine - case studies
X week lectures	Making calculations, refunds and associated administration
X week exercises	Practical part -making calculations and refunds on the recipes
XI week lectures	The possibility of making galenic and magistral preparations in public and hospital pharmacy
XI week exercises	Getting to know the specifics of production, issuance, main and galenic preparations
XII week lectures	Types of communication and establish communication
XII week exercises	Panel discussions on the subject of communication with patients giving advice
XIII week lectures	Advising patients, pharmaceutical history, debugging in medical therapy
XIII week exercises	Case study from the pharmacy - providing expert opinion, solving drug interactions, counseling patients
XIV week lectures	Sources of information in pharmacy practice and science; Pharmaceutical Information System
XIV week exercises	Ways to get acquainted with the achievements in the pharmaceutical practice, the need for continued education
XV week lectures	Preparation for final exam
XV week exercises

Student workload	4 credits x 40/30 = 5.3 hours. Structure: 2 hours of lectures, 2 hours of practical work, 1.3 hours of independent work. Lectures and the final exam (5,3hx16 = 84h). Necessary preparations before the semester begins 2hx5,3 = 10.6h. Total workload for subject 4x30 = 120h, Structure of workload 84.8 + 10.6 + 24.6 = 120h
Per week	Per semester
4 credits x 40/30=5 hours and 20 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 1 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 5 hour(s) i 20 minuts x 16 =85 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 5 hour(s) i 20 minuts x 2 =10 hour(s) i 40 minuts Total workload for the subject: 4 x 30=120 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 24 hour(s) i 0 minuts Workload structure: 85 hour(s) i 20 minuts (cources), 10 hour(s) i 40 minuts (preparation), 24 hour(s) i 0 minuts (additional work)
Student obligations	Attendance to lectures and practical part is obligatory. Writing and presenting seminar papers is obligatory and it is assessed
Consultations	Professor and teaching associates have consultations with students once a week in the period defined at the beginning of the academic year
Literature	1.Farmakopeja , 2.Evropska farmakopeja, 3. Registar ljekova I Farmakoterapijski vodiči, 4.Važeća zakonska akta, 5. Remington:Science and Practice of Pharmacy, Lippincott and Wilkins, 21st.Ed 2005, Martindale, Complete Drug Reference 34th edition, 2004;6.
Examination methods	Attendance at lectures: 0-5 points; The presence and activiy 0-5poena; Presentation of the cases I, II: 0-10; 0-10 points; Colloquium. 0-20poena Final exam: 0-50 points
Special remarks	none
Comment	none

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / COMMUNICATION SKILLS IN PHARMACY

Course:

COMMUNICATION SKILLS IN PHARMACY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
13254	Obavezan	9	5	2+1+0

Programs	PHARMACY
Prerequisites	No.
Aims	Acquiring new theoretical knowledge and improving communication skills as professional competencies in healthcare, Applying specific communication skills (assertiveness, empathy, active listening), Understanding the methods and importance of communication within the healthcare team, Explaining the specifics of communication with patients, Analyzing potential communication barriers and demonstrating ways to overcome them, Explaining the specifics of communication with patients
Learning outcomes	After attending lectures and exercises, students will gain knowledge and skills for: 1) Understanding contemporary theoretical approaches in communication. 2) Understanding communication skills. 3) Improving communication skills. 4) Analyzing and overcoming barriers in communication.
Lecturer / Teaching assistant	dr sci Marija Đuranović, spec.
Methodology	Interactive lectures, practical training, seminars, consultations, tests

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Research on communication between healthcare professionals and patients.
I week exercises	Research on communication between healthcare professionals and patients.
II week lectures	Motivational interview.
II week exercises	Motivational interview.
III week lectures	The latest communication information technologies and communication in medicine.
III week exercises	The latest communication information technologies and communication in medicine.
IV week lectures	Communication skills with patients suffering from incurable diseases.
IV week exercises	Communication skills with patients suffering from incurable diseases.
V week lectures	Communication with elderly individuals.
V week exercises	Communication with elderly individuals.
VI week lectures	Barriers in communication with individuals with sensory impairments.
VI week exercises	Barriers in communication with individuals with sensory impairments.
VII week lectures	Communication with individuals with mental health disorders.
VII week exercises	Communication with individuals with mental health disorders.
VIII week lectures	Specifics of communication with seriously ill patients and their family members.
VIII week exercises	Specifics of communication with seriously ill patients and their family members.
IX week lectures	Mandatory qualities of healthcare professionals and rules of good communication.
IX week exercises	Mandatory qualities of healthcare professionals and rules of good communication.
X week lectures	Tolerance as a prerequisite for successful communication.
X week exercises	Tolerance as a prerequisite for successful communication.
XI week lectures	Utilizing empathy in patient communication.
XI week exercises	Utilizing empathy in patient communication.
XII week lectures	The binding attitudes and communication of healthcare professionals towards their colleagues.
XII week exercises	The binding attitudes and communication of healthcare professionals towards their colleagues.
XIII week lectures	"Burnout" among pharmaceutical staff.
XIII week exercises	"Burnout" among pharmaceutical staff.
XIV week lectures	Therapy for professional burnout.
XIV week exercises	Team work.
XV week lectures	Team work.
XV week exercises	Test.

Student workload	In the semester: Teaching and final exam: (6.66 hours) x 16 = 106.66 hours Necessary preparations before the start of the semester (administration, enrollment, verification): (6.66 hours) x 2 = 13.33 hours Total workload for the subject: 5 x 30 = 150 hours Load structure: 106.66 hours (teaching and final exam) + 13.33 hours (preparation) + 30 hours (additional work) Passing the exam implies cumulatively achieving 50 points or more.
Per week	Per semester
5 credits x 40/30=6 hours and 40 minuts 2 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 3 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 6 hour(s) i 40 minuts x 16 =106 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 6 hour(s) i 40 minuts x 2 =13 hour(s) i 20 minuts Total workload for the subject: 5 x 30=150 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 30 hour(s) i 0 minuts Workload structure: 106 hour(s) i 40 minuts (cources), 13 hour(s) i 20 minuts (preparation), 30 hour(s) i 0 minuts (additional work)
Student obligations	Test.
Consultations	Regular attendance of classes and exercises, completion of seminar papers.
Literature	1. Nenadović, M. Milutin (2010) Vjestina komuniciranja, Beograd; 2. Đordjević.B, Braš, M.(2011) Komunikacija u medicini, čovjek je čovjeku lijek, Medicinska naklada, Zagreb; 3. Mandić;Т.(2003) Komunikologija : psihologija komunikacije 4. izdanje. Klio, Beograd
Examination methods	Test: (0-40 points) Seminar paper: (0-10 points) Final exam: (0-50 points)
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BASIC OF PHARMACEUTICAL MANAGEMENT

Course:

BASIC OF PHARMACEUTICAL MANAGEMENT/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7634	Obavezan	9	7	3++0

Programs	PHARMACY
Prerequisites	None
Aims	The goal of studying the subject is that students become familiar with the general and basic principles of modern business/management, the need for the development of work organizations, and to master healthcare system management. Additionally, the aim is for the student to acquire knowledge in organizing the pharmaceutical sector and to gain skills in the pharmaceutical market for goods and services.
Learning outcomes	The ability to understand fundamental processes in management that the student should successfully demonstrate after the learning process, focusing specifically on managing organizations, with an emphasis on healthcare systems.
Lecturer / Teaching assistant	Zorica Potpara, PhD, Assoc. Prof
Methodology	Lectures, practical classes (workshops), seminars, and consultations

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to pharmaceutical management
I week exercises	Familiarization with management in pharmacy, examples
II week lectures	Basic organization theories; quality system management; organizational changes, organizational models
II week exercises	Discussions – quality system, significance of quality in pharmacy
III week lectures	Healthcare system management; health policy
III week exercises	Panel discussions - healthcare system in Montenegro
IV week lectures	Management in the pharmaceutical industry and pharmacy
IV week exercises	Panel discussion on topics from the functions of management
V week lectures	National drug policy; logistics and supply of public health
V week exercises	Discussions - drug lists
VI week lectures	National procurement law and practices in drug procurement
VI week exercises	Panel discussion and case analysis
VII week lectures	Pharmaceutical market and business of generic drugs
VII week exercises	Examples of generic drug brands
VIII week lectures	Marketing concept of drugs social value
VIII week exercises	Workshop – examples of marketing strategies and methods in selected therapeutic drug groups for chosen markets
IX week lectures	Methods and strategies in pharmaceutical marketing
IX week exercises	Selected therapeutic drug groups and their marketing
X week lectures	Supplier chain - good pharmaceutical practice standards
X week exercises	Discussions on drug wholesale
XI week lectures	Management of public pharmacy
XI week exercises	Examples of pharmaceutical health services processes
XII week lectures	Project management in health promotion
XII week exercises	Examples and discussions on health promotion
XIII week lectures	Information and Communication Technologies (ICT) in health and drug promotion
XIII week exercises	Discussions on communication in the pharmaceutical sector
XIV week lectures	Competitive pharmacy
XIV week exercises	Panel discussion on the topic of competitive pharmacy
XV week lectures	Management of pharmaceutical waste
XV week exercises	Panel discussions on pharmaceutical waste

Student workload	Weekly 7 credits x 40/30 = 9.33 hours. Structure: 3 hours of lectures 6.33 hours of independent student work. Teaching and final exam: (9.33 hours) x 16 = 149.33 hours. Necessary preparations before the beginning of the semester (administration, enrollment, verification): (9.33 hours) x 2 = 18.66 hours. Total course workload: 7 x 30 = 210 hours. Workload structure: 149.33 hours (teaching and final exam) + 18.66 hours (preparation) + 42 hours (overtime)
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 0 excercises 6 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance in lectures and practical sessions. Continuous acquisition of knowledge and skills.
Consultations	With the subject teacher according to established schedules
Literature	1.Winfield A.J. Pharmaceutical Practice, Churchill Livingstone third ed.2004. 2. Smith M.C., Wertheimer A.I. Social and behavioral aspects of pharmaceutical care. Pharmaceutical Press. 1996. 3. Smith F. Research Methods in Pharmacy Practice. Pharmaceutical Press. 2005. 4. Kayne SB. Pharmacy business management. Pharmaceutical Products Press. 2005. 5. Remington: Science and Practice of Pharmacy. Lippincott Williams and Wilkins 21st ed.2005
Examination methods	Pre-examination requirements: 50 points attendance at lectures (0-8 points); practical teaching (seminars, panel discussions) (0-22 points); Test: (0-20 points). Final exam: (0-50 points). Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50
Special remarks	None
Comment	Additional information about the subject can be obtained from the subject teacher

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / COMMUNICATION SKILLS IN PHARMACY

Course:

COMMUNICATION SKILLS IN PHARMACY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
13252	Obavezan	9	7	4+2+0

Programs	PHARMACY
Prerequisites	No.
Aims	Acquiring new theoretical knowledge and improving communication skills as professional competencies in healthcare, Applying specific communication skills (assertiveness, empathy, active listening), Understanding the methods and importance of communication within the healthcare team, Explaining the specifics of communication with patients, Analyzing potential communication barriers and demonstrating ways to overcome them, Explaining the specifics of communication with patients
Learning outcomes	After attending lectures and exercises, students will gain knowledge and skills for: 1) Understanding contemporary theoretical approaches in communication. 2) Understanding communication skills. 3) Improving communication skills. 4) Analyzing and overcoming barriers in communication.
Lecturer / Teaching assistant	dr sci Marija Đuranović, spec.
Methodology	Interactive lectures, practical training, seminars, consultations, tests

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Research on communication between healthcare professionals and patients.
I week exercises	Research on communication between healthcare professionals and patients.
II week lectures	Motivational interview.
II week exercises	Motivational interview.
III week lectures	The latest communication information technologies and communication in medicine.
III week exercises	The latest communication information technologies and communication in medicine.
IV week lectures	Communication skills with patients suffering from incurable diseases.
IV week exercises	Communication skills with patients suffering from incurable diseases.
V week lectures	Communication with elderly individuals.
V week exercises	Communication with elderly individuals.
VI week lectures	Barriers in communication with individuals with sensory impairments.
VI week exercises	Barriers in communication with individuals with sensory impairments.
VII week lectures	Communication with individuals with mental health disorders.
VII week exercises	Communication with individuals with mental health disorders.
VIII week lectures	Specifics of communication with seriously ill patients and their family members.
VIII week exercises	Specifics of communication with seriously ill patients and their family members.
IX week lectures	Mandatory qualities of healthcare professionals and rules of good communication.
IX week exercises	Mandatory qualities of healthcare professionals and rules of good communication.
X week lectures	Tolerance as a prerequisite for successful communication.
X week exercises	Tolerance as a prerequisite for successful communication.
XI week lectures	Utilizing empathy in patient communication.
XI week exercises	Utilizing empathy in patient communication.
XII week lectures	The binding attitudes and communication of healthcare professionals towards their colleagues.
XII week exercises	The binding attitudes and communication of healthcare professionals towards their colleagues.
XIII week lectures	"Burnout" among pharmaceutical staff.
XIII week exercises	"Burnout" among pharmaceutical staff.
XIV week lectures	Therapy for professional burnout.
XIV week exercises	Team work.
XV week lectures	Team work.
XV week exercises	Test.

Student workload	In the semester: Teaching and final exam: (6.66 hours) x 16 = 106.66 hours Necessary preparations before the start of the semester (administration, enrollment, verification): (6.66 hours) x 2 = 13.33 hours Total workload for the subject: 5 x 30 = 150 hours Load structure: 106.66 hours (teaching and final exam) + 13.33 hours (preparation) + 30 hours (additional work)
Per week	Per semester
7 credits x 40/30=9 hours and 20 minuts 4 sat(a) theoretical classes 0 sat(a) practical classes 2 excercises 3 hour(s) i 20 minuts of independent work, including consultations	Classes and final exam: 9 hour(s) i 20 minuts x 16 =149 hour(s) i 20 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 9 hour(s) i 20 minuts x 2 =18 hour(s) i 40 minuts Total workload for the subject: 7 x 30=210 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 42 hour(s) i 0 minuts Workload structure: 149 hour(s) i 20 minuts (cources), 18 hour(s) i 40 minuts (preparation), 42 hour(s) i 0 minuts (additional work)
Student obligations	Test.
Consultations	Regular attendance of classes and exercises, completion of seminar papers.
Literature	1. Nenadović, M. Milutin (2010) Vjestina komuniciranja, Beograd; 2. Đordjević.B, Braš, M.(2011) Komunikacija u medicini, čovjek je čovjeku lijek, Medicinska naklada, Zagreb; 3. Mandić;Т.(2003) Komunikologija : psihologija komunikacije 4. izdanje. Klio, Beograd
Examination methods	Exam: (0-40 points) Seminar paper: (0-10 points) Final exam: (0-50 points) Passing the exam implies cumulatively achieving 50 points or more.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL PRACTICE

Course:

PHARMACEUTICAL PRACTICE/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
6768	Obavezan	9	8	3+3+0

Programs	PHARMACY
Prerequisites	Does not have
Aims	Understanding the role and place of pharmacists in the primary, secondary and tertiary levels of health care, familiarization with medicines, lists of medicines and medical devices. Getting to know the quality control measures of medicines, monitoring the occurrence of falsified medicines and reporting them to competent institutions. Familiarization with the administration process in the pharmaceutical industry, with the procedures for dispensing finished drugs and medical devices
Learning outcomes	1. Recognize the role and place of pharmacists in the primary, secondary and tertiary levels of health care; 2. Knows the essential and national list of medicines and notices the difference; 3. Identifies measures to check the quality of medicines, monitors the occurrence of falsified medicines and their reporting to competent institutions; 4. Uses acquired knowledge in the production of magisterial and galenic medicines, issuing ready-made medicines and medical devices; 5. Perform calculations, refunds and do the following administration; 6. Knows styles and types of communication (patient, professional and general public); 7. Uses acquired knowledge to advise patients, on pharmaceutical anamnesis and to eliminate possible errors in drug therapy.
Lecturer / Teaching assistant	Asst. Dr. Tanja Vojinović
Methodology	Lectures, laboratory exercises, consultations, practical preparations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Health systems
I week exercises	Definitions of pharmaceutical practice, activities, comparison with pharmaceutical practice in the region
II week lectures	WHO, FDA, WSMI AND Essential Medicines List
II week exercises	Acquaintance with drug lists, WHO and FDA recommendations, in the area of prescribing prescriptions
III week lectures	Drug lists (national and hospital)
III week exercises	Panel discussions - lists of medicines, examples of the national list of medicines
IV week lectures	Public and hospital pharmacies as part of the health care system
IV week exercises	Getting to know the types of pharmacies and the activities performed in them
V week lectures	Activities in daily practice in the public pharmacy (planning, procurement, storage, dispensing, distribution). Colloquium I.
V week exercises	Getting to know the simulating pharmacy, simulating working with patients, issuing prescriptions
VI week lectures	Activities in daily practice in the hospital pharmacy
VI week exercises	Panel discussion on the topic of drug dispensing in a hospital pharmacy and the specifics of working in a hospital pharmacy
VII week lectures	Pharmaceutical products - groups, forms, qualifications
VII week exercises	Familiarity with pharmaceutical products, groups and forms
VIII week lectures	Medical devices and products in the function of health (preventive, diagnostic, therapeutic and rehabilitation means)
VIII week exercises	Acquaintance with medical devices, types, ways of dispensing
IX week lectures	Prescription and dispensing of finished drugs, medical devices and OTC
IX week exercises	Prescription drug dispensing – case analysis
X week lectures	Preparation of calculations, refunds and accompanying administration. Colloquium II.
X week exercises	Practical exercises - making calculations and refunds on prescriptions
XI week lectures	Practical exercises - making calculations and refunds on prescriptions
XI week exercises	Familiarization with the specifics of making, issuing, magisterial and galenic preparations
XII week lectures	Types of communication and establishing communication
XII week exercises	Panel discussions on the topic of communication with patients and giving advice
XIII week lectures	Patient counseling, pharmaceutical anamnesis, elimination of errors in drug therapy
XIII week exercises	Presentation of a case from a pharmacy - giving an expert opinion, solving drug interactions, counseling patients
XIV week lectures	Reliable sources of information in pharmaceutical practice and science
XIV week exercises	Ways of familiarizing yourself with the achievements in pharmaceutical practice, the need for continuous education
XV week lectures	Pharmaceutical information system
XV week exercises	Various opportunities to familiarize yourself with the information system

Student workload	Weekly 8 credits x 40/30 = 11 hours. Structure: 3 hours of lectures, 3 hours of exercises, 5 hours of independent work including consultations. In the semester Classes and final exam 11 hours x 16 = 176 hours Necessary preparations before the beginning of the semester (administration, registration, certification) 2 x 11 hours = 22 hours Total load on the course: 8 x 30 = 240 hours. Additional work: 42 hours Load structure: 176 hours (teaching) + 22 hours (preparation) + 42 hours (additional work) = 240 hours
Per week	Per semester
8 credits x 40/30=10 hours and 40 minuts 3 sat(a) theoretical classes 0 sat(a) practical classes 3 excercises 4 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 10 hour(s) i 40 minuts x 16 =170 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 10 hour(s) i 40 minuts x 2 =21 hour(s) i 20 minuts Total workload for the subject: 8 x 30=240 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 48 hour(s) i 0 minuts Workload structure: 170 hour(s) i 40 minuts (cources), 21 hour(s) i 20 minuts (preparation), 48 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance of classes and exercises
Consultations	Consultations with the subject teacher according to established terms
Literature	1. European Pharmacopoeia (Ph. Eur.) 10th Edition 2019. 2. Tadić I., Odalović M., Lakić D., Krajnović D., Farmaceutska praks. Beograd. 2019. 3. Registar ljekova u Crnoj Gori. 2017. 4. Remington:Science and Practice of Pharmacy, Lippincott and Wilkins. 21st.Ed 2005. 5. Martindale, Complete Drug Reference 34th edition. 2004 6. Wingield A.J:Pharmaceutical Practice, Churchill Livingstone, 3rd edition, 2004. 7. .Wertheimer S., Social and behaviora aspects of Pharmaceutical care. Pharmacy Press. 1996. 8. . Felicity S. Research Methods in Pharmacy Practice. Pharmaceutical Press. 2005
Examination methods	Attendance at lectures: (0-5 points); Attendance and activity at exercises (0-5 points); Colloquiums: (0-30) = (0-15)+ (0-15)+ Presentation of cases I, II: (0-10 points) Final exam (0-50 points) Grade: A B C D E F Number of points: 90-100 80-89 70-79 60-69 50-59 < 50 A passing grade is obtained if a cumulative minimum of 50 points is collected
Special remarks	Does not have
Comment	Additional information for the subject can be obtained from the subject teacher

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACOEPIDEMIOLOGY AND PHARMACOECONOMICS

Course:

PHARMACOEPIDEMIOLOGY AND PHARMACOECONOMICS/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7633	Obavezan	9	8	4++3

Programs	PHARMACY
Prerequisites	Pharmacology II
Aims	Providing basic knowledge in the field of pharmacoepidemiology and pharmacoeconomics. Training for critical evaluation of information in the field of pharmacoepidemiology and pharmacoeconomics. Introduction with research methods in these areas
Learning outcomes	1. use basic concepts in the field of pharmaco-epidemiology and pharmaco-economics; 2. understand the basic epidemiological studies used to test the use and side effects of medicines; 3. understand basic pharmaco-economics analysis; 4. know the principles of controlled use of medicines; 5. know systems of reporting adverse effects of medicines.
Lecturer / Teaching assistant	Prof. dr Boban Mugoša
Methodology	Interactive lectures, panel discussions, workshops, exercises

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Task of farmakoepidemiology and pharmacoeconomics.
I week exercises	Task of farmakoepidemiology and pharmacoeconomics.
II week lectures	Rational use of medicines
II week exercises	Rational use of medicines
III week lectures	Basic principles of pharmacoepidemiology methods of collection, processing and analysis of data related to the use of drugs and medical products. Using pharmacoepidemiological database
III week exercises	Basic principles of pharmacoepidemiology methods of collection, processing and analysis of data related to the use of drugs and medical products. Using pharmacoepidemiological database
IV week lectures	Methods of detection of adverse and beneficial effects of drugs, including spontaneous reporting, ad hoc epidemiological studies and usage of databases
IV week exercises	Methods of detection of adverse and beneficial effects of drugs, including spontaneous reporting, ad hoc epidemiological studies and usage of databases
V week lectures	Study design. Cross-section studies, observation studies (cohort studies and case-control) and clinical studies
V week exercises	Study design. Cross-section studies, observation studies (cohort studies and case-control) and clinical studies
VI week lectures	Study of medication use. Bias.
VI week exercises	Study of medication use. Bias.
VII week lectures	Colloquium
VII week exercises
VIII week lectures	Reporting adverse effects of drug. The preparation of reports on drug safety
VIII week exercises	Reporting adverse effects of drug. The preparation of reports on drug safety
IX week lectures	Health Economics. Calculating the cost of prevention, diagnosis and treatment.
IX week exercises	Health Economics. Calculating the cost of prevention, diagnosis and treatment
X week lectures	Health technology and suitability assessment.Health, social and economic aspects and outcomes of medication use.
X week exercises	Health technology and suitability assessment.Health, social and economic aspects and outcomes of medication use.
XI week lectures	Using pharmacoeconomic database
XI week exercises	Using pharmacoeconomic database
XII week lectures	Basic principles of pharmacoeconomic methods of collecting, processing and analyzing data. CMA, CEA, CBA, CUA studies.
XII week exercises	Basic principles of pharmacoeconomic methods of collecting, processing and analyzing data. CMA, CEA, CBA, CUA studies.
XIII week lectures	Assessment and selection of pharmacoeconomic method for certain treatments
XIII week exercises	Assessment and selection of pharmacoeconomic method for certain treatments
XIV week lectures	Life quality related to health. Exercise - Using basic tool (questionnaire EQL) to measure life quality
XIV week exercises	Life quality related to health. Exercise - Using basic tool (questionnaire EQL) to measure life quality
XV week lectures	Final exam
XV week exercises

Student workload	Weekly: 4 credits x 40/30 = 5 h 30min Structure: 2 hour lecturing, 1 hour exercise, 2 hours and 30 minutes for individual work During the semester: lecturing and final exam (5h 30 min x 16 = 85 hours) Necessary preparation (before semester enrollment, etc ...) 2h X 5 hours and 30 minutes = 10 hours Total load: 4 x 30 = 120h Additional work 25h Load structure 85h + 10h + 25h = 120 hours
Per week	Per semester
8 credits x 40/30=10 hours and 40 minuts 4 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 3 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 10 hour(s) i 40 minuts x 16 =170 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 10 hour(s) i 40 minuts x 2 =21 hour(s) i 20 minuts Total workload for the subject: 8 x 30=240 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 48 hour(s) i 0 minuts Workload structure: 170 hour(s) i 40 minuts (cources), 21 hour(s) i 20 minuts (preparation), 48 hour(s) i 0 minuts (additional work)
Student obligations	Regular attending at lectures and exercises, presentation of seminar paper, passing colloquiums and final exam
Consultations	Wednesday, 10:00-12:00h
Literature	1. Strom BL, Pharmacoepidemiology, 2nd ed John Wiley Sons, Chic ester, New York, Brisbane, Toronto, Singapore, 1994; 2. Hartzema AG, Porta M, Tilson HH. Pharmacoepidemiology, Cincinnati: Harvey Whitney; 3. Drummond m et al. Methods for the Economic Eva
Examination methods	Presence at lecturing (0-5 points) Practical classes (0-10 points) Seminar (0-10 points) Colloquium (0-25 points) Final exam (0-50 points) StudThe exam is passed with cumulative 51 points
Special remarks
Comment	Additional information can be received from the subject teacher, head of the study program and Dean for Academic Affairs

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / CLINICAL PHARMACY

Course:

CLINICAL PHARMACY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7635	Obavezan	9	8	3++3

Programs	PHARMACY
Prerequisites	Pharmacotherapy I, II, Pharmacokinetics
Aims	Developing the knowledge, skills, and attitudes necessary for applying the principles of clinical pharmacy in everyday pharmaceutical practice, with a focus on therapy optimization, patient safety, and rational use of medicines in both hospital and outpatient settings.
Learning outcomes	Upon completion of the course, the student will be able to recognize, analyze, and solve pharmacotherapeutic problems by applying the principles of clinical pharmacy, utilizing clinical guidelines, pharmacokinetic parameters, and patient-centered pharmaceutical care. The student will also develop skills in patient counseling, team communication, and evaluation of therapeutic safety and efficacy.
Lecturer / Teaching assistant	Dr sci. med. Miloš Krivokapić
Methodology	Interactive lectures, practical classes (input-exit test, case workshops - Workshop, presentations of solving cases by topic).

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Introduction to Clinical Pharmacy: definition, history, role of the clinical pharmacist
I week exercises	Introduction to Clinical Pharmacy: differences between clinical pharmacy and clinical pharmacology
II week lectures	Health System and the Role of the Clinical Pharmacist in a Team-Based Approach
II week exercises	Analysis of Medication Errors and Clinical Consequences; Evidence-Based Medicine (EBM) Tools
III week lectures	Applied Pharmacokinetics in Clinical Practice
III week exercises	Case Work – Calculation and Application of Pharmacokinetic Parameters
IV week lectures	Clinical Trials, Pharmacovigilance, and Clinical Audit
IV week exercises	Identification of Drug Interactions and Adverse Drug Reactions
V week lectures	Evidence-Based Pharmacy, Sources of Drug Information
V week exercises	Evaluation of Clinical Sources and Guidelines through Case Studies
VI week lectures	Interpretation of Laboratory Findings in Clinical Pharmacy
VI week exercises	Interpretation and Application of Laboratory Results in Therapeutic Decision-Making
VII week lectures	Rational Pharmacotherapy – Focus on Therapeutic Groups (Part I)
VII week exercises	Workshop – Case Analysis with a Focus on Cardiological and Antimicrobial Drugs
VIII week lectures	Rational Pharmacotherapy – Focus on Therapeutic Groups (Part II)
VIII week exercises	Workshop – Cases on Diabetes, Depression, and Anticoagulants
IX week lectures	Pharmacotherapy in Special Populations (Children, Pregnant Women, Elderly)
IX week exercises	Therapy Adjustment in Special Populations (Children, Pregnant Women, Elderly)
X week lectures	Drug Interactions and Prevention of Medical Errors
X week exercises	Simulation of Therapeutic Errors – Developing Recommendations and Prevention Strategies
XI week lectures	Patient Counseling and Communication Skills
XI week exercises	Simulation of Communication with Patients and Medication Education
XII week lectures	Self-Medication and Medication Dispensing Regimens
XII week exercises	Risk Assessment in OTC Use; Preparing Patient Advice
XIII week lectures	Pharmacovigilance and Drug Safety; Counterfeit Medicines
XIII week exercises	Reporting Adverse Drug Reactions
XIV week lectures	Rational Pharmacotherapy Based on Population Data and Pharmacoeconomic Analysis
XIV week exercises	Clinical Case Analysis Through the Lens of Rationality, Epidemiological Relevance, and Economic Justification of Therapy
XV week lectures	Integration of Clinical Pharmacy: Knowledge Synthesis and Competency Evaluation, Future of Clinical Pharmacy
XV week exercises	Final Workshop: Designing an Intervention for a Specific Patient + Portfolio

Student workload	In the semester Teaching and final exam: (10.66 hours) x 16 = 170.56 hours Necessary preparations before the start semester (administration, registration, certification): (10.66 hours) x 2 = 21.32 hours Total workload for the course: 8 x 30 = 240 hours Load structure: 170.56 hours (classes and final exam) + 21.32 hours (preparation) + 48 hours (supplementary work).
Per week	Per semester
8 credits x 40/30=10 hours and 40 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 4 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 10 hour(s) i 40 minuts x 16 =170 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 10 hour(s) i 40 minuts x 2 =21 hour(s) i 20 minuts Total workload for the subject: 8 x 30=240 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 48 hour(s) i 0 minuts Workload structure: 170 hour(s) i 40 minuts (cources), 21 hour(s) i 20 minuts (preparation), 48 hour(s) i 0 minuts (additional work)
Student obligations	Attendance and active participation in theoretical and practical classes, as well as all forms of knowledge testing mandatory.
Consultations	The subject teacher and professional associates hold consultations with students once a week at term that is defined at the beginning of the study year.
Literature	Vezmar Kovačević S, Miljković B. Clinical Pharmacy: In Theory and Practice. 2nd ed. Belgrade: University of Belgrade – Faculty of Pharmacy; 2021. Prostran M, editor. Clinical Pharmacology: Selected Chapters. Belgrade: Faculty of Medicine, University of Belgrade; 2018. Walker R, Whittlesea C, editors. Clinical Pharmacy and Therapeutics. Božikov V, editor of the Croatian edition. Zagreb: Školska knjiga; 2004.
Examination methods	Colloquium I: 0–20 points. Colloquium II: 0–20 points. Preparation and presentation of the seminar paper: 0–10 points. The final exam is oral (0–50 points). A passing grade is awarded if a minimum of 50 points is accumulated in total.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / PHARMACEUTICAL REGULATION FROM THE ASPECT OF MEDIC

Course:

PHARMACEUTICAL REGULATION FROM THE ASPECT OF MEDIC/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
13253	Obavezan	9	8	4+1+0

Programs	PHARMACY
Prerequisites
Aims	Acquiring knowledge in the field of national and EU legislation related to the quality of medicines for use in human medicine.
Learning outcomes	1. Apply the acquired knowledge in the evaluation of the documentation on the quality of the medicine. 2. Interpret and apply valid regulatory requirements from the aspect of medicine quality.
Lecturer / Teaching assistant	Tijana Mićović
Methodology	Lectures, practical teaching (workshops; seminar papers), consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Availability of quality, safe and effective medicines in modern society. Drug life cycle. National procedure and EU procedures for issuing a license to place a medicine on the market; license renewal; changes and additions to the drug license (variations).
I week exercises	Overview of national and EU legislation related to the quality of medicines for use in human medicine.
II week lectures	Structure of the common technical document (The Common Technical Document, CTD). Module 3 – data on the quality of the drug (pharmaceutical-chemical-biological data).
II week exercises	Workshop/seminar work on a topic related to the previous lecture.
III week lectures	Development, production, quality and stability of the active substance (Active Substance Master File procedure, ASMF). Certificate of Suitability to Monograph of the European Pharmacopoeia.
III week exercises	Workshop/seminar work on a topic related to the previous lecture.
IV week lectures	Pharmaceutical drug development.
IV week exercises	Workshop/seminar work on a topic related to the previous lecture.
V week lectures	Medicines - pharmaceutical forms; the specification of the drug when releasing a batch of the drug into circulation; specification within the period of use of the drug. Skip tests. Quality control of the active substance and medicine. Development and validation of analytical methods.
V week exercises	Workshop/seminar work on a topic related to the previous lecture.
VI week lectures	Impurities in active substances and medicines. Classification and definition of specification limits.
VI week exercises	Workshop/seminar work on a topic related to the previous lecture.
VII week lectures	Stability of active substances and medicines. Stability monitoring conditions; stability protocols of active substances and medicines.
VII week exercises	Workshop/seminar work on a topic related to the previous lecture.
VIII week lectures	Accelerated stability studies; long-term stability studies; stress stability studies. Defining the re-test period for active substances and the shelf life of the drug, as well as storage conditions depending on the results of stability studies.
VIII week exercises	Workshop/seminar work on a topic related to the previous lecture.
IX week lectures	Production of medicines. Validation of the production process.
IX week exercises	Workshop/seminar work on a topic related to the previous lecture.
X week lectures	Sterile drugs. Sterilization procedures.
X week exercises	Workshop/seminar work on a topic related to the previous lecture.
XI week lectures	Quality of packaging material - active substances and medicines.
XI week exercises	Workshop/seminar work on a topic related to the previous lecture.
XII week lectures	Colloquium
XII week exercises	Workshop/seminar work on a topic related to the previous lecture.
XIII week lectures	Genotoxic impurities.
XIII week exercises	Workshop/seminar work on a topic related to the previous lecture.
XIV week lectures	Biological drugs.
XIV week exercises	Workshop/seminar work on a topic related to the previous lecture.
XV week lectures	Final exam
XV week exercises	Workshop/seminar work on a topic related to the previous lecture.

Student workload	In the semester Teaching and final exam: (10.66 hours) x 16 = 170.56 hours Necessary preparations before the beginning of the semester (administration, registration, certification): (10.66 hours) x 2 = 21.32 hours Total workload for the course : 8 x 30 = 240 hours Load structure: 170.56 hours (classes and final exam) + 21.32 hours (preparation) + 48 hours (supplementary work)
Per week	Per semester
8 credits x 40/30=10 hours and 40 minuts 4 sat(a) theoretical classes 0 sat(a) practical classes 1 excercises 5 hour(s) i 40 minuts of independent work, including consultations	Classes and final exam: 10 hour(s) i 40 minuts x 16 =170 hour(s) i 40 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 10 hour(s) i 40 minuts x 2 =21 hour(s) i 20 minuts Total workload for the subject: 8 x 30=240 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 48 hour(s) i 0 minuts Workload structure: 170 hour(s) i 40 minuts (cources), 21 hour(s) i 20 minuts (preparation), 48 hour(s) i 0 minuts (additional work)
Student obligations	Attendance at theoretical and practical classes and all forms of knowledge testing. Participation in discussions/interactive teaching.
Consultations
Literature	European Pharmacopoeia, current edition; EU Legislation – Eudralex; European Medicines Agency - scientific guidelines (quality); ICH quality guidelines; EDQM&HealthCare (European Directorate for the Quality of Medicines and HealthCare); CInMED (Institute for Medicines and Medical Devices of Montenegro) portal - regulation in the field of medicines for use in human medicine - quality.
Examination methods	Pre-examination requirements - 50 points: attendance at lectures (0-5 points); active participation in workshops/seminar papers (0-15 points + 0-15 points); colloquium (0-15 points). The final exam is written (0-50 points). A passing grade is obtained if a cumulative minimum of 50 points is collected.
Special remarks
Comment

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Faculty of Medicine / PHARMACY / BASICS OF INDUSTRIAL PHARMACY

Course:

BASICS OF INDUSTRIAL PHARMACY/

Course ID	Course status	Semester	ECTS credits	Lessons (Lessons+Exercises+Laboratory)
7632	Obavezan	9	9	3++3

Programs	PHARMACY
Prerequisites	None
Aims	The goal of the course is that students become familiar with and understand the principles and specificities of industrial drug production, including approaches to formulation development, drug stability, regulatory requirements, providing conditions for drug production, types and selection of devices used in drug manufacturing, quality systems, and quality assurance.
Learning outcomes	Applies acquired knowledge necessary for the formulation, development, and stability of medicinal products in the development laboratory or pharmaceutical industry. Understands modern requirements for the quality system in the pharmaceutical industry. Utilizes acquired knowledge of the principles and types of devices used in the pharmaceutical industry in the production of medicinal products. Applies regulatory requirements related to the development, production, quality assurance, validation, storage, and distribution of drugs. Familiar with regulations for placing a drug on the market. Applies acquired knowledge to perform various tasks in the research of formulations for different pharmaceutical forms. Understands the concept, types, definitions, and significance of "good practices" in pharmaceutical activities
Lecturer / Teaching assistant	Zorica Potpara, PhD, Assoc. Prof Nataša Radonjić, MPharm, teaching assist.
Methodology	Lectures, practical classes (workshops), seminars, consultations.

Plan and program of work
Preparing week	Preparation and registration of the semester
I week lectures	Development of control and quality management in drug manufacturing
I week exercises	Problem-solving in the development of control and quality management in drug manufacturing
II week lectures	Good practices in the pharmaceutical industry, concept, and types
II week exercises	Explanation of basic concepts and types of good practices in the pharmaceutical industry
III week lectures	Good manufacturing practices
III week exercises	Explanation of the significance of good manufacturing practices
IV week lectures	Validation, definition, significance, and application area. Test I
IV week exercises	Computational problems
V week lectures	Drug registration
V week exercises	Computer search for guidelines related to drug registration
VI week lectures	Significance of pre-formulation and formulation research in the pharmaceutical industry
VI week exercises	Explanation of concepts and possible problems in pre-formulation and formulation research in the pharmaceutical industry
VII week lectures	Drug stability. Stability testing of drugs in the pharmaceutical industry
VII week exercises	Review of guidelines for stability testing of drugs and computational problems
VIII week lectures	Selected pharmaceutical-technological operations in drug manufacturing
VIII week exercises	Explanation of the significance of pharmaceutical-technological operations in the pharmaceutical industry
IX week lectures	Mixing. Test II
IX week exercises	Understanding the practical significance of mixing in the pharmaceutical industry
X week lectures	Granulation
X week exercises	Understanding the practical significance of granulation in the pharmaceutical Industry
XI week lectures	Compression
XI week exercises	Understanding the practical significance of compression in the pharmaceutical Industry
XII week lectures	Tablet Coating
XII week exercises	Presentation of problems that can occur during coating of pharmaceutical forms in the pharmaceutical industr
XIII week lectures	Sterilization of preparations
XIII week exercises	Practical significance of sterilization in industrial production of pharmaceutical forms
XIV week lectures	Pharmaceutical operation - packaging
XIV week exercises	Significance of packaging in the final phase of industrial production
XV week lectures	Final consultations - for the exam
XV week exercises	Practical exam

Student workload	Weekly 9 credits x 40/30 = 12 hours. Structure: 3 hours of lectures, 3 hours of exercises, 6 hours of individual student work. Teaching and final exam: (12 hours) x 16 = 192 hours Necessary preparations before the beginning of the semester (administration, enrollment, verification): (12 hours) x 2 = 24 hours. Total workload for the course: 9 x 30 = 270 hours. Structure workload: 192 hours (teaching and final exam) + 24 hours (preparation) + 54 hours (additional work)
Per week	Per semester
9 credits x 40/30=12 hours and 0 minuts 3 sat(a) theoretical classes 3 sat(a) practical classes 0 excercises 6 hour(s) i 0 minuts of independent work, including consultations	Classes and final exam: 12 hour(s) i 0 minuts x 16 =192 hour(s) i 0 minuts Necessary preparation before the beginning of the semester (administration, registration, certification): 12 hour(s) i 0 minuts x 2 =24 hour(s) i 0 minuts Total workload for the subject: 9 x 30=270 hour(s) Additional work for exam preparation in the preparing exam period, including taking the remedial exam from 0 to 30 hours (remaining time from the first two items to the total load for the item) 54 hour(s) i 0 minuts Workload structure: 192 hour(s) i 0 minuts (cources), 24 hour(s) i 0 minuts (preparation), 54 hour(s) i 0 minuts (additional work)
Student obligations	Regular attendance in lectures and practical sessions. Continuous acquisition of knowledge and skills.
Consultations	Consultations with the subject teacher according to established schedules.
Literature	Milica Jovanović, Zorica Đurić, "Fundamentals of industrial pharmacy," Nijansa, Zemun, 2005; Carstensen J., "Drug Stability," 2nd ed. Marcel Dekker, New York, 1995
Examination methods	Attendance in lectures (0-5 points); Activity in exercises and preparation of exercises (0-5); Tests: 40 points (0-20 + 0-20) Final exam: 0-50 points Grade: A B C D E F Points: 90-100 80-89 70-79 60-69 50-59 <50
Special remarks
Comment	None.

Grade:	F	E	D	C	B	A
Number of points	less than 50 points	greater than or equal to 50 points and less than 60 points	greater than or equal to 60 points and less than 70 points	greater than or equal to 70 points and less than 80 points	greater than or equal to 80 points and less than 90 points	greater than or equal to 90 points

Accesibility Adjustments

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE

Faculty of Medicine / PHARMACY / ANATOMY

Faculty of Medicine / PHARMACY / BIOLOGY WITH HUMAN GENETICS

Faculty of Medicine / PHARMACY / PHYSICS

Faculty of Medicine / PHARMACY / INTRODUCTION TO PHARMACY

Faculty of Medicine / PHARMACY / MATHEMATICS

Faculty of Medicine / PHARMACY / ORGANIC CHEMISTRY I

Faculty of Medicine / PHARMACY / GENERAL AND INORGANIC CHEMISTRY

Faculty of Medicine / PHARMACY / METHODOLOGY OF SCIENTIFIC WORK

Faculty of Medicine / PHARMACY / GRADUATION PAPER

Faculty of Medicine / PHARMACY / PROFESSINAL PRACTICE

Faculty of Medicine / PHARMACY / UNDERGRADUATE PRACTICE

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE

Faculty of Medicine / PHARMACY / HYSTOLOGY

Faculty of Medicine / PHARMACY / ANATOMY AND HISTOLOGY

Faculty of Medicine / PHARMACY / ANALYTICAL CHEMISTRY I

Faculty of Medicine / PHARMACY / BOTANICS

Faculty of Medicine / PHARMACY / ORGANIC CHEMISTRY II

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE I

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE I

Faculty of Medicine / PHARMACY / COLOIDAL AND SURFACE CHEMISTRY

Faculty of Medicine / PHARMACY / IMMUNOLOGY

Faculty of Medicine / PHARMACY / PHYSICAL CHEMISTRY

Faculty of Medicine / PHARMACY / PHARMACEUTICAL MICROBIOLOGY

Faculty of Medicine / PHARMACY / PHISIOLOGY I

Faculty of Medicine / PHARMACY / ANALYTICAL CHEMISTRY II

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE II

Faculty of Medicine / PHARMACY / ENGLISH LANGUAGE II

Faculty of Medicine / PHARMACY / GENERAL BIOCHEMISTRY

Faculty of Medicine / PHARMACY / PHISIOLOGY II

Faculty of Medicine / PHARMACY / PHARMACEUTICAL CHEMISTRY I

Faculty of Medicine / PHARMACY / INSTRUMENTAL METHODS

Faculty of Medicine / PHARMACY / PHARMACOGNOSY I

Faculty of Medicine / PHARMACY / PHARMACEUTICAL BIOCHEMISTRY

Faculty of Medicine / PHARMACY / DIETETICS

Faculty of Medicine / PHARMACY / PATHOPHYSIOLOGY

Faculty of Medicine / PHARMACY / PATHOLOGICAL PHYSIOLOGY

Faculty of Medicine / PHARMACY / BROMATOLOGY

Faculty of Medicine / PHARMACY / PHARMACOGNOSY II

Faculty of Medicine / PHARMACY / PHARMACOLOGY I

Faculty of Medicine / PHARMACY / PHARMACEUTICAL CHEMISTRY II

Faculty of Medicine / PHARMACY / PHARMACOLOGY II

Faculty of Medicine / PHARMACY / MEDICAL BIOCHEMISTRY

Faculty of Medicine / PHARMACY / PHARMACEUTICAL CHEMISTRY III

Faculty of Medicine / PHARMACY / PHARMACEUTICAL TECHNOLOGY I

Faculty of Medicine / PHARMACY / PHARMACEUTICAL STATISTICS

Faculty of Medicine / PHARMACY / PHYTOTHERAPY

Faculty of Medicine / PHARMACY / COSMETOLOGY

Faculty of Medicine / PHARMACY / PHARMACOTHERAPY I

Faculty of Medicine / PHARMACY / PHARMACEUTICAL TECHNOLOGY II

Faculty of Medicine / PHARMACY / PHARAMACEUTICAL ANALISYS AND MEDICINES CONTROL

Faculty of Medicine / PHARMACY / DERMATOCOSMETICS PREPARATIONS

Faculty of Medicine / PHARMACY / PHARAMACEUTICAL ETHICS AND LAW

Faculty of Medicine / PHARMACY / BIOPHARMACEUTICS

Faculty of Medicine / PHARMACY / PHARMACOTHERAPY II

Faculty of Medicine / PHARMACY / TOXICOLOGY WITH ANALYTICS

Faculty of Medicine / PHARMACY / PHARMACEUTICAL TECHNOLOGY III

Faculty of Medicine / PHARMACY / BIOPHARMACEUTICS WITH PHARMACOKINETICS

Faculty of Medicine / PHARMACY / MODERN PHARMACEUTICAL FORMULATIONS

Faculty of Medicine / PHARMACY / ANALYTICAL CHEMISTRY IN PHARMACEUTICAL PRACTICE I

Faculty of Medicine / PHARMACY / PHARMACEUTICAL PRACTICE I

Faculty of Medicine / PHARMACY / COMMUNICATION SKILLS IN PHARMACY

Faculty of Medicine / PHARMACY / BASIC OF PHARMACEUTICAL MANAGEMENT

Faculty of Medicine / PHARMACY / COMMUNICATION SKILLS IN PHARMACY

Faculty of Medicine / PHARMACY / PHARMACEUTICAL PRACTICE

Faculty of Medicine / PHARMACY / PHARMACOEPIDEMIOLOGY AND PHARMACOECONOMICS

Faculty of Medicine / PHARMACY / CLINICAL PHARMACY

Faculty of Medicine / PHARMACY / PHARMACEUTICAL REGULATION FROM THE ASPECT OF MEDIC

Faculty of Medicine / PHARMACY / BASICS OF INDUSTRIAL PHARMACY